ESPR (Esperion Therapeutics) EV-to-EBITDA: 11.52 (As of Aug. 05, 2026)

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ESPR Esperion Therapeutics Inc ESPR
62 GF Score
Price $3.18
GF Value $2.30
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is Esperion Therapeutics EV-to-EBITDA?

Esperion Therapeutics ESPR -0.31% 62 EV-to-EBITDA is 11.52 as of Aug. 05, 2026. GuruFocus rates ESPR with a GF Score™ of 62/100 and a GF Value™ of $2.30 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 746 Drug Manufacturers companies, Esperion Therapeutics ranks better than 55.36% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Esperion Therapeutics's enterprise value is $915.9 Mil. Esperion Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $79.5 Mil. Therefore, Esperion Therapeutics's EV-to-EBITDA for today is 11.52.

The historical rank and industry rank for Esperion Therapeutics's EV-to-EBITDA or its related term are showing as below:

ESPR' s EV-to-EBITDA Range Over the Past 10 Years
Min: -37.51   Med: -3.67   Max: 80.67
Current: 11.52

During the past 13 years, the highest EV-to-EBITDA of Esperion Therapeutics was 80.67. The lowest was -37.51. And the median was -3.67.

ESPR's EV-to-EBITDA is ranked better than
55.36% of 746 companies
in the Drug Manufacturers industry
Industry Median: 13.08 vs ESPR: 11.52

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-05), Esperion Therapeutics's stock price is $3.18. Esperion Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-0.100. Therefore, Esperion Therapeutics's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Esperion Therapeutics  (NAS:ESPR) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Esperion Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=3.18/-0.100
=At Loss

Esperion Therapeutics's share price for today is $3.18.
Esperion Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.100.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Esperion Therapeutics EV-to-EBITDA Related Terms


Esperion Therapeutics EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Esperion Therapeutics's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Esperion Therapeutics EV-to-EBITDA Chart

Esperion Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1.37 -3.17 -3.58 77.12 15.53

Esperion Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -5.27 -12.72 -27.76 15.53 10.09

ESPR vs AMPH, NIKA, BIOA: EV-to-EBITDA Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Esperion Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Esperion Therapeutics EV-to-EBITDA vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Esperion Therapeutics's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Esperion Therapeutics's EV-to-EBITDA falls into.


ESPR
62GF Score
Esperion Therapeutics Inc ESPR
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Esperion Therapeutics EV-to-EBITDA Calculation

Esperion Therapeutics's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=915.935/79.495
=11.52

Esperion Therapeutics's current Enterprise Value is $915.9 Mil.
Esperion Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $79.5 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of 11.52 mean?
Esperion Therapeutics (ESPR) has a EV-to-EBITDA of 11.52 as of Aug. 05, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Esperion Therapeutics. According to the industry distribution chart, Esperion Therapeutics ranks #333 out of 746 companies in the Drug Manufacturers industry, placing it in the top 44.6%.
Is Esperion Therapeutics' EV-to-EBITDA too high?
Esperion Therapeutics' current EV-to-EBITDA is 11.52. The Drug Manufacturers industry median EV-to-EBITDA is 13.08. Esperion Therapeutics' value of 11.52 is 11.9% below this industry median. Based on the distribution chart, Esperion Therapeutics ranks #333 out of 746 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Esperion Therapeutics has a GF Score™ of 62/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Esperion Therapeutics' EV-to-EBITDA compare to AMPH and NIKA?
According to the Drug Manufacturers industry distribution chart, Esperion Therapeutics ranks #333 out of 746 companies for EV-to-EBITDA. This puts Esperion Therapeutics in the upper half of its industry. The industry median EV-to-EBITDA is 13.08. Esperion Therapeutics' value of 11.52 is 11.9% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Drug Manufacturers company?
The median EV-to-EBITDA among Drug Manufacturers companies is 13.08, based on 746 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Esperion Therapeutics's current EV-to-EBITDA of 11.52 is 11.9% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Esperion Therapeutics. For the Drug Manufacturers industry, the median EV-to-EBITDA is 13.08 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Esperion Therapeutics's current EV-to-EBITDA is 11.52. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Esperion Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Esperion Therapeutics (ESPR) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.30, compared to a current price of $3.18 — trading 38.3% above its estimated fair value. The current EV-to-EBITDA is 11.52 and 11.9% below the Drug Manufacturers industry median of 13.08. Esperion Therapeutics' overall GF Score™ is 62/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Esperion Therapeutics (ESPR), the current EV-to-EBITDA is 11.52 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Esperion Therapeutics (ESPR) Overvalued in 2026?

Based on GuruFocus' analysis, Esperion Therapeutics stock appears to be overvalued. The current stock price of $3.18 is trading 38.3% above its estimated GF Value™ of $2.30. GuruFocus considers Esperion Therapeutics to be Significantly Overvalued.

Key valuation signals for ESPR:

  • EV-to-EBITDA: 11.52
  • GF Value™: $2.30 vs. price of $3.18 (38.3% above fair value)
  • GF Score™: 62/100 with 6 warning signs
  • Industry Position: 11.9% below the Drug Manufacturers median (#333 of 746)

No single metric tells the full story. See the ESPR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Esperion Therapeutics Business Description

Other Exchanges 0IIM:UK0ET:Germany
Address 3891 Ranchero Drive, Suite 150, Ann Arbor, MI, USA, 48108
Esperion Therapeutics Inc is a commercial-stage biopharmaceutical company currently focused on bringing new medicines to patients that address unmet medical needs. It has developed and is commercializing U.S. Food and Drug Administration, or FDA, approved oral, once-daily, non-statin medicines for patients who are at risk for cardiovascular disease (or CVD and are struggling with elevated low-density lipoprotein cholesterol, or LDL-C. The Company views its operations and manages its business in one operating segment, which is the business of researching, developing, and commercializing therapies for the treatment of patients with elevated LDL-C. The company depends almost entirely on the success of two products, the bempedoic acid tablet and the bempedoic acid/ezetimibe combination tablet.
62GF Score

Get the complete analysis for ESPR

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.18
Price
$2.30
GF Value