ESPR (Esperion Therapeutics) Net Margin %: -31.45% (As of Mar. 2026)

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ESPR Esperion Therapeutics Inc ESPR
62 GF Score
Price $3.18
GF Value $2.30
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Esperion Therapeutics Net Margin %?

Esperion Therapeutics ESPR -0.31% 62 Net Margin % is -31.45% as of Mar. 2026. GuruFocus rates ESPR with a GF Score™ of 62/100 and a GF Value™ of $2.30 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 962 Drug Manufacturers companies, Esperion Therapeutics ranks worse than 68.5% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Esperion Therapeutics's Net Income for the three months ended in Mar. 2026 was $-25.2 Mil. Esperion Therapeutics's Revenue for the three months ended in Mar. 2026 was $80.1 Mil. Therefore, Esperion Therapeutics's net margin for the quarter that ended in Mar. 2026 was -31.45%.

The historical rank and industry rank for Esperion Therapeutics's Net Margin % or its related term are showing as below:

ESPR' s Net Margin % Range Over the Past 10 Years
Min: -343.04   Med: -65.49   Max: -1.78
Current: -1.78


ESPR's Net Margin % is ranked worse than
68.5% of 962 companies
in the Drug Manufacturers industry
Industry Median: 5.37 vs ESPR: -1.78

Esperion Therapeutics  (NAS:ESPR) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Esperion Therapeutics Net Margin % Related Terms


Esperion Therapeutics Net Margin % Historical Data

* Premium members only.

The historical data trend for Esperion Therapeutics's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Esperion Therapeutics Net Margin % Chart

Esperion Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -343.04 -309.58 -179.87 -15.57 -5.63

Esperion Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -62.24 -15.45 -35.89 36.71 -31.45

ESPR vs AMPH, NIKA, BIOA: Net Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Esperion Therapeutics's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Esperion Therapeutics Net Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Esperion Therapeutics's Net Margin % distribution charts can be found below:

* The bar in red indicates where Esperion Therapeutics's Net Margin % falls into.


ESPR
62GF Score
Esperion Therapeutics Inc ESPR
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Esperion Therapeutics Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Esperion Therapeutics's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-22.682/403.135
=-5.63 %

Esperion Therapeutics's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-25.196/80.104
=-31.45 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -31.45% mean?
Esperion Therapeutics (ESPR) has a Net Margin % of -31.45% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Esperion Therapeutics and its competitors. According to the industry distribution chart, Esperion Therapeutics ranks #659 out of 962 companies in the Drug Manufacturers industry, placing it in the top 68.5%.
Is Esperion Therapeutics' Net Margin % too high?
Esperion Therapeutics' current Net Margin % is -31.45%. Based on the distribution chart, Esperion Therapeutics ranks #659 out of 962 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Esperion Therapeutics has a GF Score™ of 62/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Esperion Therapeutics' Net Margin % compare to AMPH and NIKA?
According to the Drug Manufacturers industry distribution chart, Esperion Therapeutics ranks #659 out of 962 companies for Net Margin %. This places Esperion Therapeutics in the lower half of its industry. The industry median Net Margin % is 5.37. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Drug Manufacturers company?
The median Net Margin % among Drug Manufacturers companies is 5.37, based on 962 companies in the industry. Companies in the top quartile (top 25%) have a Net Margin % significantly above this median, while those in the bottom quartile fall well below. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Esperion Therapeutics and its competitors. For the Drug Manufacturers industry, the median Net Margin % is 5.37 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Esperion Therapeutics's current Net Margin % is -31.45%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Esperion Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Esperion Therapeutics (ESPR) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.30, compared to a current price of $3.18 — trading 38.3% above its estimated fair value. The current Net Margin % is -31.45%. Esperion Therapeutics' overall GF Score™ is 62/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Esperion Therapeutics (ESPR), the current Net Margin % is -31.45% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Esperion Therapeutics (ESPR) Overvalued in 2026?

Based on GuruFocus' analysis, Esperion Therapeutics stock appears to be overvalued. The current stock price of $3.18 is trading 38.3% above its estimated GF Value™ of $2.30. GuruFocus considers Esperion Therapeutics to be Significantly Overvalued.

Key valuation signals for ESPR:

  • Net Margin %: -31.45%
  • GF Value™: $2.30 vs. price of $3.18 (38.3% above fair value)
  • GF Score™: 62/100 with 6 warning signs

No single metric tells the full story. See the ESPR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Esperion Therapeutics Business Description

Other Exchanges 0IIM:UK0ET:Germany
Address 3891 Ranchero Drive, Suite 150, Ann Arbor, MI, USA, 48108
Esperion Therapeutics Inc is a commercial-stage biopharmaceutical company currently focused on bringing new medicines to patients that address unmet medical needs. It has developed and is commercializing U.S. Food and Drug Administration, or FDA, approved oral, once-daily, non-statin medicines for patients who are at risk for cardiovascular disease (or CVD and are struggling with elevated low-density lipoprotein cholesterol, or LDL-C. The Company views its operations and manages its business in one operating segment, which is the business of researching, developing, and commercializing therapies for the treatment of patients with elevated LDL-C. The company depends almost entirely on the success of two products, the bempedoic acid tablet and the bempedoic acid/ezetimibe combination tablet.
62GF Score

Get the complete analysis for ESPR

Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.18
Price
$2.30
GF Value