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Pliant TherapeuticsPLRX -2.73%31 EV-to-EBITDA is 0.69 as of Jul. 22, 2026. GuruFocus rates PLRX with a GF Score™ of 31/100. The stock has 2 warning signs investors should review. Among 398 Biotechnology companies, Pliant Therapeutics ranks better than 81.66% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Pliant Therapeutics's enterprise value is $-75.85 Mil.
Pliant Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-109.95 Mil. Therefore, Pliant Therapeutics's EV-to-EBITDA for today is 0.69.
The historical rank and industry rank for Pliant Therapeutics's EV-to-EBITDA or its related term are showing as below:
PLRX'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -28.08 Med: -2.22 Max: 41.99
Current: 0.69
During the past 8 years, the highest EV-to-EBITDA of Pliant Therapeutics was 41.99. The lowest was -28.08. And the median was -2.22.
PLRX's EV-to-EBITDA is ranked better than 81.66% of 398
companies
in the Biotechnology industry
Industry Median: 12.295
vs PLRX: 0.69
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Pliant Therapeutics's PE Ratio (TTM) for today is calculated as:
Pliant Therapeutics's share price for today is $1.07.
Pliant Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.840.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Pliant Therapeutics's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Pliant Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Pliant Therapeutics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Pliant Therapeutics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Pliant Therapeutics's EV-to-EBITDA falls into.
Pliant Therapeutics's current Enterprise Value is $-75.85 Mil.
Pliant Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-109.95 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Pliant Therapeutics (PLRX) has a EV-to-EBITDA of 0.69 as of Jul. 22, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Pliant Therapeutics. According to the industry distribution chart, Pliant Therapeutics ranks #73 out of 398 companies in the Biotechnology industry, placing it in the top 18.3%.
Is Pliant Therapeutics' EV-to-EBITDA too high?
Pliant Therapeutics' current EV-to-EBITDA is 0.69. The Biotechnology industry median EV-to-EBITDA is 12.30. Pliant Therapeutics' value of 0.69 is 94.4% below this industry median. Based on the distribution chart, Pliant Therapeutics ranks #73 out of 398 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Pliant Therapeutics has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Pliant Therapeutics' EV-to-EBITDA compare to BYSI and MCRB?
According to the Biotechnology industry distribution chart, Pliant Therapeutics ranks #73 out of 398 companies for EV-to-EBITDA. This places Pliant Therapeutics in the top 18% of its industry — outperforming the majority of peers. The industry median EV-to-EBITDA is 12.30. Pliant Therapeutics' value of 0.69 is 94.4% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.30, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Pliant Therapeutics's current EV-to-EBITDA of 0.69 is 94.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Pliant Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 12.30 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Pliant Therapeutics's current EV-to-EBITDA is 0.69. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pliant Therapeutics stock overvalued right now?
Pliant Therapeutics (PLRX) has a current EV-to-EBITDA of 0.69. The current EV-to-EBITDA is 0.69 and 94.4% below the Biotechnology industry median of 12.30. Pliant Therapeutics' overall GF Score™ is 31/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Pliant Therapeutics (PLRX), the current EV-to-EBITDA is 0.69 as of Jul. 22, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company engaged in the discovery and development of integrin-based therapies. The company operates as a single reportable segment focused on developing and commercializing novel integrin-based treatments. Its lead product candidate, PLN-101095, is an oral small molecule targeting integrins for the treatment of solid tumors. The company also advances a pipeline of integrin-based programs across multiple disease areas through its proprietary drug discovery platform.
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