PLRX (Pliant Therapeutics) ROE % Adjusted to Book Value: -98.49% (As of Mar. 2026)


PLRX Pliant Therapeutics Inc PLRX
31 GF Score
Price $1.11
! 2 Warning Signs
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What is Pliant Therapeutics ROE % Adjusted to Book Value?

Pliant Therapeutics PLRX -1.77% 31 ROE % Adjusted to Book Value is -98.49% as of Mar. 2026. GuruFocus rates PLRX with a GF Score™ of 31/100. The stock has 2 warning signs investors should review.

Pliant Therapeutics's ROE % for the quarter that ended in Mar. 2026 was -46.29%. Pliant Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 0.47. Pliant Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -98.49%.

Pliant Therapeutics ROE % Adjusted to Book Value Related Terms

Pliant Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Pliant Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Pliant Therapeutics ROE % Adjusted to Book Value Chart

Pliant Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial -16.47 -15.94 -17.90 -20.49 -150.12

Pliant Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -250.19 -226.81 -111.22 -120.59 -98.49

PLRX vs RLYB, LIXT, CSBR: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Pliant Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Pliant Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Pliant Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Pliant Therapeutics's ROE % Adjusted to Book Value falls into.


PLRX
31GF Score
Pliant Therapeutics Inc PLRX
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Pliant Therapeutics ROE % Adjusted to Book Value Calculation

Pliant Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-61.55% / 0.41
=-150.12%

Pliant Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-46.29% / 0.47
=-98.49%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -98.49% mean?
Pliant Therapeutics (PLRX) has a ROE % Adjusted to Book Value of -98.49% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Pliant Therapeutics and its competitors.
Is Pliant Therapeutics' ROE % Adjusted to Book Value too high?
Pliant Therapeutics' current ROE % Adjusted to Book Value is -98.49%. Overall, Pliant Therapeutics has a GF Score™ of 31/100, reflecting its overall financial health beyond just this single metric.
How does Pliant Therapeutics' ROE % Adjusted to Book Value compare to RLYB and LIXT?
Pliant Therapeutics' ROE % Adjusted to Book Value of -98.49% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Pliant Therapeutics and its competitors. Pliant Therapeutics's current ROE % Adjusted to Book Value is -98.49%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pliant Therapeutics stock overvalued right now?
Pliant Therapeutics (PLRX) has a current ROE % Adjusted to Book Value of -98.49%. The current ROE % Adjusted to Book Value is -98.49%. Pliant Therapeutics' overall GF Score™ is 31/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Pliant Therapeutics (PLRX), the current ROE % Adjusted to Book Value is -98.49% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Pliant Therapeutics Business Description

Other Exchanges 9PT:Germany
Address 331 Oyster Point Boulevard, South San Francisco, CA, USA, 94080
Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company engaged in the discovery and development of integrin-based therapies. The company operates as a single reportable segment focused on developing and commercializing novel integrin-based treatments. Its lead product candidate, PLN-101095, is an oral small molecule targeting integrins for the treatment of solid tumors. The company also advances a pipeline of integrin-based programs across multiple disease areas through its proprietary drug discovery platform.
31GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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