RLAY (Relay Therapeutics) EV-to-EBITDA: -11.31 (As of Aug. 13, 2026)

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RLAY Relay Therapeutics Inc RLAY
53 GF Score
Price $19.93
GF Value $3.80
Valuation Significantly Overvalued
! 7 Warning Signs
View Full Analysis

What is Relay Therapeutics EV-to-EBITDA?

Relay Therapeutics RLAY -0.75% 53 EV-to-EBITDA is -11.31 as of Aug. 13, 2026. GuruFocus rates RLAY with a GF Score™ of 53/100 and a GF Value™ of $3.80 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 399 Biotechnology companies, Relay Therapeutics ranks worse than 250626.32% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Relay Therapeutics's enterprise value is $3,487.22 Mil. Relay Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $-308.22 Mil. Therefore, Relay Therapeutics's EV-to-EBITDA for today is -11.31.

The historical rank and industry rank for Relay Therapeutics's EV-to-EBITDA or its related term are showing as below:

RLAY' s EV-to-EBITDA Range Over the Past 10 Years
Min: -93.37   Med: -2.83   Max: 0.87
Current: -11.31

During the past 8 years, the highest EV-to-EBITDA of Relay Therapeutics was 0.87. The lowest was -93.37. And the median was -2.83.

RLAY's EV-to-EBITDA is ranked worse than
100% of 399 companies
in the Biotechnology industry
Industry Median: 13.39 vs RLAY: -11.31

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-13), Relay Therapeutics's stock price is $19.93. Relay Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-1.570. Therefore, Relay Therapeutics's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Relay Therapeutics  (NAS:RLAY) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Relay Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=19.93/-1.570
=At Loss

Relay Therapeutics's share price for today is $19.93.
Relay Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.570.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Relay Therapeutics EV-to-EBITDA Related Terms


Relay Therapeutics EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Relay Therapeutics's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Relay Therapeutics EV-to-EBITDA Chart

Relay Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial -10.70 -2.83 -1.89 0.11 -3.17

Relay Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.08 -1.05 -3.17 -4.33 -10.41

RLAY vs CELC, VKTX, DYN: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Relay Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Relay Therapeutics EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Relay Therapeutics's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Relay Therapeutics's EV-to-EBITDA falls into.


RLAY
53GF Score
Relay Therapeutics Inc RLAY
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
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Relay Therapeutics EV-to-EBITDA Calculation

Relay Therapeutics's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=3487.216/-308.224
=-11.31

Relay Therapeutics's current Enterprise Value is $3,487.22 Mil.
Relay Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-308.22 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -11.31 mean?
Relay Therapeutics (RLAY) has a EV-to-EBITDA of -11.31 as of Aug. 13, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Relay Therapeutics. According to the industry distribution chart, Relay Therapeutics ranks #999999 out of 399 companies in the Biotechnology industry.
Is Relay Therapeutics' EV-to-EBITDA too high?
Relay Therapeutics' current EV-to-EBITDA is -11.31. Based on the distribution chart, Relay Therapeutics ranks #999999 out of 399 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Relay Therapeutics has a GF Score™ of 53/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Relay Therapeutics' EV-to-EBITDA compare to CELC and VKTX?
According to the Biotechnology industry distribution chart, Relay Therapeutics ranks #999999 out of 399 companies for EV-to-EBITDA. This places Relay Therapeutics in the lower half of its industry. The industry median EV-to-EBITDA is 13.39. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.39, based on 399 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Relay Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 13.39 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Relay Therapeutics's current EV-to-EBITDA is -11.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Relay Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Relay Therapeutics (RLAY) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.80, compared to a current price of $19.93 — trading 424.5% above its estimated fair value. The current EV-to-EBITDA is -11.31. Relay Therapeutics' overall GF Score™ is 53/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Relay Therapeutics (RLAY), the current EV-to-EBITDA is -11.31 as of Aug. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Relay Therapeutics (RLAY) Overvalued in 2026?

Based on GuruFocus' analysis, Relay Therapeutics stock appears to be overvalued. The current stock price of $19.93 is trading 424.5% above its estimated GF Value™ of $3.80. GuruFocus considers Relay Therapeutics to be Significantly Overvalued.

Key valuation signals for RLAY:

  • EV-to-EBITDA: -11.31
  • GF Value™: $3.80 vs. price of $19.93 (424.5% above fair value)
  • GF Score™: 53/100 with 7 warning signs

No single metric tells the full story. See the RLAY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Relay Therapeutics Business Description

Address 60 Hampshire Street, Cambridge, MA, USA, 02139
Relay Therapeutics Inc is a clinical-stage precision medicine company transforming the drug discovery process and bringing life-changing therapies to patients. The Dynamo platform of the company integrates an array of leading-edge computational and experimental approaches designed to drug-protein targets that have previously been intractable or inadequately addressed. The company is advancing a pipeline of medicine candidates to address targets in precision oncology and genetic disease, including product candidates, RLY-8186, RLY-2608, RLY-4008 and others.
53GF Score

Get the complete analysis for RLAY

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$19.93
Price
$3.80
GF Value