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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Carna Biosciences's enterprise value is 円9,410.3 Mil.
Carna Biosciences's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was 円-2,160.3 Mil. Therefore, Carna Biosciences's EV-to-EBITDA for today is -4.36.
The historical rank and industry rank for Carna Biosciences's EV-to-EBITDA or its related term are showing as below:
TSE:4572'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -88.84 Med: -7.41 Max: 42.23
Current: -4.36
During the past 13 years, the highest EV-to-EBITDA of Carna Biosciences was 42.23. The lowest was -88.84. And the median was -7.41.
TSE:4572's EV-to-EBITDA is ranked worse than 100% of 407
companies
in the Biotechnology industry
Industry Median: 14.17
vs TSE:4572: -4.36
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Carna Biosciences's PE Ratio (TTM) for today is calculated as:
Carna Biosciences's share price for today is 円403.00.
Carna Biosciences's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-114.270.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Carna Biosciences's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
TSE:4572 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Carna Biosciences's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Carna Biosciences EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Carna Biosciences's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Carna Biosciences's EV-to-EBITDA falls into.
Carna Biosciences's current Enterprise Value is 円9,410.3 Mil.
Carna Biosciences's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-2,160.3 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Carna Biosciences (TSE:4572) has a EV-to-EBITDA of -4.36 as of Aug. 23, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Carna Biosciences. According to the industry distribution chart, Carna Biosciences ranks #999999 out of 407 companies in the Biotechnology industry.
Is Carna Biosciences' EV-to-EBITDA too high?
Carna Biosciences' current EV-to-EBITDA is -4.36. Based on the distribution chart, Carna Biosciences ranks #999999 out of 407 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Carna Biosciences has a GF Score™ of 28/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Carna Biosciences' EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Carna Biosciences ranks #999999 out of 407 companies for EV-to-EBITDA. This places Carna Biosciences in the lower half of its industry. The industry median EV-to-EBITDA is 14.17. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.17, based on 407 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Carna Biosciences. For the Biotechnology industry, the median EV-to-EBITDA is 14.17 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Carna Biosciences's current EV-to-EBITDA is -4.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Carna Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Carna Biosciences (TSE:4572) is currently considered Significantly Overvalued. The stock's GF Value™ is 円205.22, compared to a current price of 円403.00 — trading 96.4% above its estimated fair value. The current EV-to-EBITDA is -4.36. Carna Biosciences' overall GF Score™ is 28/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Carna Biosciences (TSE:4572), the current EV-to-EBITDA is -4.36 as of Aug. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Carna Biosciences (TSE:4572) Overvalued in 2026?
Based on GuruFocus' analysis, Carna Biosciences stock appears to be overvalued.
The current stock price of 円403.00 is trading 96.4% above its estimated GF Value™ of 円205.22.
GuruFocus considers Carna Biosciences to be Significantly Overvalued.
Key valuation signals for TSE:4572:
EV-to-EBITDA: -4.36
GF Value™: 円205.22 vs. price of 円403.00 (96.4% above fair value)
No single metric tells the full story. See the TSE:4572 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Carna Biosciences Inc is a Japanese company engaged in drug discovery support business and drug discovery and development business. The company identifies and develops medicines for the treatment of cancer and inflammatory diseases using own kinase drug discovery platform, QuickScout.
28GF Score
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