Carna Biosciences (TSE:4572) ROE % Adjusted to Book Value: 0.00% (As of Dec. 2025)


TSE:4572 Carna Biosciences Inc TSE:4572
24 GF Score
Price 円337.00
GF Value 円174.75
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is Carna Biosciences ROE % Adjusted to Book Value?

Carna Biosciences TSE:4572 -0.59% 24 ROE % Adjusted to Book Value is 0.00% as of Dec. 2025. GuruFocus rates TSE:4572 with a GF Score™ of 24/100 and a GF Value™ of 円174.75 (Significantly Overvalued). The stock has 6 warning signs investors should review.

Carna Biosciences's ROE % for the quarter that ended in Dec. 2025 was 0.00%. Carna Biosciences's PB Ratio for the quarter that ended in Dec. 2025 was 22.04. Carna Biosciences's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was 0.00%.

Carna Biosciences ROE % Adjusted to Book Value Related Terms

Carna Biosciences ROE % Adjusted to Book Value Historical Data

* Premium members only.

The historical data trend for Carna Biosciences's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Carna Biosciences ROE % Adjusted to Book Value Chart

Carna Biosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -3.86 -16.71 -13.27 -29.69 -7.08

Carna Biosciences Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -31.84 -27.91 0.00 0.00

TSE:4572 vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Carna Biosciences's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Carna Biosciences ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Carna Biosciences's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Carna Biosciences's ROE % Adjusted to Book Value falls into.


TSE:4572
24GF Score
Carna Biosciences Inc TSE:4572
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Carna Biosciences ROE % Adjusted to Book Value Calculation

Carna Biosciences's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-155.96% / 22.04
=-7.08%

Carna Biosciences's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=0.00% / 22.04
=0.00%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 0.00% mean?
Carna Biosciences (TSE:4572) has a ROE % Adjusted to Book Value of 0.00% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Carna Biosciences and its competitors.
Is Carna Biosciences' ROE % Adjusted to Book Value too high?
Carna Biosciences' current ROE % Adjusted to Book Value is 0.00%. Overall, Carna Biosciences has a GF Score™ of 24/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Carna Biosciences' ROE % Adjusted to Book Value compare to VRTX and REGN?
Carna Biosciences' ROE % Adjusted to Book Value of 0.00% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Carna Biosciences and its competitors. Carna Biosciences's current ROE % Adjusted to Book Value is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Carna Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Carna Biosciences (TSE:4572) is currently considered Significantly Overvalued. The stock's GF Value™ is 円174.75, compared to a current price of 円337.00 — trading 92.8% above its estimated fair value. The current ROE % Adjusted to Book Value is 0.00%. Carna Biosciences' overall GF Score™ is 24/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Carna Biosciences (TSE:4572), the current ROE % Adjusted to Book Value is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Carna Biosciences (TSE:4572) Overvalued in 2026?

Based on GuruFocus' analysis, Carna Biosciences stock appears to be overvalued. The current stock price of 円337.00 is trading 92.8% above its estimated GF Value™ of 円174.75. GuruFocus considers Carna Biosciences to be Significantly Overvalued.

Key valuation signals for TSE:4572:

  • ROE % Adjusted to Book Value: 0.00%
  • GF Value™: 円174.75 vs. price of 円337.00 (92.8% above fair value)
  • GF Score™: 24/100 with 6 warning signs

No single metric tells the full story. See the TSE:4572 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Carna Biosciences Business Description

Address BMA 3F 1-5-5 Minatojima-Minamimachi, Kobe, JPN, 650-0047
Carna Biosciences Inc is a Japanese company engaged in drug discovery support business and drug discovery and development business. The company identifies and develops medicines for the treatment of cancer and inflammatory diseases using own kinase drug discovery platform, QuickScout.
24GF Score

Get the complete analysis for TSE:4572

ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円337.00
Price
円174.75
GF Value