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EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, CytomX Therapeutics's Enterprise Value is $430.45 Mil.
CytomX Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-82.41 Mil. Therefore, CytomX Therapeutics's EV-to-OCF for today is -5.22.
The historical rank and industry rank for CytomX Therapeutics's EV-to-OCF or its related term are showing as below:
CTMX'
s EV-to-OCF Range Over the Past 10 Years
Min: -229.45 Med: -0.15 Max: 24.37
Current: -5.22
During the past 13 years, the highest EV-to-OCF of CytomX Therapeutics was 24.37. The lowest was -229.45. And the median was -0.15.
CTMX's EV-to-OCF is ranked better than 57.21% of 1407
companies
in the Biotechnology industry
Industry Median: -3.45
vs CTMX: -5.22
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
CytomX Therapeutics's PE Ratio (TTM) for today is calculated as:
CytomX Therapeutics's share price for today is $3.465.
CytomX Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.500.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
CytomX Therapeutics EV-to-OCF Related Terms
CytomX Therapeutics EV-to-OCF Historical Data
* Premium members only.
The historical data trend for CytomX Therapeutics's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, CytomX Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
CytomX Therapeutics EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, CytomX Therapeutics's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where CytomX Therapeutics's EV-to-OCF falls into.
CytomX Therapeutics's current Enterprise Value is $430.45 Mil.
CytomX Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-82.41 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
CytomX Therapeutics (CTMX) has a EV-to-OCF of -5.22 as of Aug. 09, 2026. According to the industry distribution chart, CytomX Therapeutics ranks #602 out of 1407 companies in the Biotechnology industry, placing it in the top 42.8%.
Is CytomX Therapeutics' EV-to-OCF too high?
CytomX Therapeutics' current EV-to-OCF is -5.22. Based on the distribution chart, CytomX Therapeutics ranks #602 out of 1407 companies in the Biotechnology industry, which is above the industry midpoint. Overall, CytomX Therapeutics has a GF Score™ of 36/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CytomX Therapeutics' EV-to-OCF compare to BBOT and OMER?
According to the Biotechnology industry distribution chart, CytomX Therapeutics ranks #602 out of 1407 companies for EV-to-OCF. This puts CytomX Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. CytomX Therapeutics's current EV-to-OCF is -5.22. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CytomX Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, CytomX Therapeutics (CTMX) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.12, compared to a current price of $3.47 — trading 2787.5% above its estimated fair value. The current EV-to-OCF is -5.22. CytomX Therapeutics' overall GF Score™ is 36/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For CytomX Therapeutics (CTMX), the current EV-to-OCF is -5.22 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is CytomX Therapeutics (CTMX) Overvalued in 2026?
Based on GuruFocus' analysis, CytomX Therapeutics stock appears to be overvalued.
The current stock price of $3.47 is trading 2787.5% above its estimated GF Value™ of $0.12.
GuruFocus considers CytomX Therapeutics to be Significantly Overvalued.
Key valuation signals for CTMX:
EV-to-OCF: -5.22
GF Value™: $0.12 vs. price of $3.47 (2787.5% above fair value)
No single metric tells the full story. See the CTMX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
CytomX Therapeutics Inc a clinical-stage, oncology-focused biopharmaceutical company developing novel, masked, conditionally activated biologics designed to be localized to the tumor microenvironment. It is engaged in developing antibody therapeutics based on probody technology platforms. The company's probody technology platform creates proprietary cancer immunotherapies against clinically-validated targets and develops cancer therapeutics. Probody therapeutics are designed to take advantage of conditions in the tumor microenvironment to enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues.
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