CTMX (CytomX Therapeutics) Pretax Margin %: -177.32% (As of Mar. 2026)


CTMX CytomX Therapeutics Inc CTMX
36 GF Score
Price $3.31
GF Value $0.28
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is CytomX Therapeutics Pretax Margin %?

CytomX Therapeutics CTMX -0.45% 36 Pretax Margin % is -177.32% as of Mar. 2026. GuruFocus rates CTMX with a GF Score™ of 36/100 and a GF Value™ of $0.28 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 947 Biotechnology companies, CytomX Therapeutics ranks worse than 56.71% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. CytomX Therapeutics's Pre-Tax Income for the three months ended in Mar. 2026 was $-18.19 Mil. CytomX Therapeutics's Revenue for the three months ended in Mar. 2026 was $10.26 Mil. Therefore, CytomX Therapeutics's pretax margin for the quarter that ended in Mar. 2026 was -177.32%.

The historical rank and industry rank for CytomX Therapeutics's Pretax Margin % or its related term are showing as below:

CTMX' s Pretax Margin % Range Over the Past 10 Years
Min: -495.32   Med: -116.61   Max: 23.24
Current: -165.74


CTMX's Pretax Margin % is ranked worse than
56.71% of 947 companies
in the Biotechnology industry
Industry Median: -90.63 vs CTMX: -165.74

CytomX Therapeutics  (NAS:CTMX) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


CytomX Therapeutics Pretax Margin % Related Terms


CytomX Therapeutics Pretax Margin % Historical Data

* Premium members only.

The historical data trend for CytomX Therapeutics's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CytomX Therapeutics Pretax Margin % Chart

CytomX Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -310.54 -186.82 3.28 23.24 -22.48

CytomX Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 46.32 -0.49 -237.65 -3,990.35 -177.32

CTMX vs SMNR, AURA, OMER: Pretax Margin % Comparison

For the Biotechnology subindustry, CytomX Therapeutics's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CytomX Therapeutics Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CytomX Therapeutics's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where CytomX Therapeutics's Pretax Margin % falls into.


CTMX
36GF Score
CytomX Therapeutics Inc CTMX
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

CytomX Therapeutics Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

CytomX Therapeutics's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-17.13/76.201
=-22.48 %

CytomX Therapeutics's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-18.189/10.258
=-177.32 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -177.32% mean?
CytomX Therapeutics (CTMX) has a Pretax Margin % of -177.32% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on CytomX Therapeutics and its competitors. According to the industry distribution chart, CytomX Therapeutics ranks #537 out of 947 companies in the Biotechnology industry, placing it in the top 56.7%.
Is CytomX Therapeutics' Pretax Margin % too high?
CytomX Therapeutics' current Pretax Margin % is -177.32%. Based on the distribution chart, CytomX Therapeutics ranks #537 out of 947 companies in the Biotechnology industry, which is below the industry midpoint. Overall, CytomX Therapeutics has a GF Score™ of 36/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CytomX Therapeutics' Pretax Margin % compare to SMNR and AURA?
According to the Biotechnology industry distribution chart, CytomX Therapeutics ranks #537 out of 947 companies for Pretax Margin %. This places CytomX Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on CytomX Therapeutics and its competitors. CytomX Therapeutics's current Pretax Margin % is -177.32%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CytomX Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, CytomX Therapeutics (CTMX) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.28, compared to a current price of $3.31 — trading 1080.4% above its estimated fair value. The current Pretax Margin % is -177.32%. CytomX Therapeutics' overall GF Score™ is 36/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For CytomX Therapeutics (CTMX), the current Pretax Margin % is -177.32% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CytomX Therapeutics (CTMX) Overvalued in 2026?

Based on GuruFocus' analysis, CytomX Therapeutics stock appears to be overvalued. The current stock price of $3.31 is trading 1080.4% above its estimated GF Value™ of $0.28. GuruFocus considers CytomX Therapeutics to be Significantly Overvalued.

Key valuation signals for CTMX:

  • Pretax Margin %: -177.32%
  • GF Value™: $0.28 vs. price of $3.31 (1080.4% above fair value)
  • GF Score™: 36/100 with 4 warning signs

No single metric tells the full story. See the CTMX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CytomX Therapeutics Business Description

Other Exchanges 6C1:Germany
Address 151 Oyster Point Boulevard, Suite 400, South San Francisco, CA, USA, 94080
CytomX Therapeutics Inc a clinical-stage, oncology-focused biopharmaceutical company developing novel, masked, conditionally activated biologics designed to be localized to the tumor microenvironment. It is engaged in developing antibody therapeutics based on probody technology platforms. The company's probody technology platform creates proprietary cancer immunotherapies against clinically-validated targets and develops cancer therapeutics. Probody therapeutics are designed to take advantage of conditions in the tumor microenvironment to enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues.
36GF Score

Get the complete analysis for CTMX

Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.31
Price
$0.28
GF Value