CTMX (CytomX Therapeutics) OCF Margin %: -249.06% (As of Mar. 2026)


CTMX CytomX Therapeutics Inc CTMX
36 GF Score
Price $3.26
GF Value $0.28
Valuation Significantly Overvalued
! 4 Warning Signs
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What is CytomX Therapeutics OCF Margin %?

CytomX Therapeutics CTMX -1.96% 36 OCF Margin % is -249.06% as of Mar. 2026. GuruFocus rates CTMX with a GF Score™ of 36/100 and a GF Value™ of $0.28 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 960 Biotechnology companies, CytomX Therapeutics ranks worse than 62.81% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. CytomX Therapeutics's Cash Flow from Operations for the three months ended in Mar. 2026 was $-25.55 Mil. CytomX Therapeutics's Revenue for the three months ended in Mar. 2026 was $10.26 Mil. Therefore, CytomX Therapeutics's OCF Margin % for the quarter that ended in Mar. 2026 was -249.06%.

As of today, CytomX Therapeutics's current OCF Yield % is -11.30%.

The historical rank and industry rank for CytomX Therapeutics's OCF Margin % or its related term are showing as below:

CTMX' s OCF Margin % Range Over the Past 10 Years
Min: -522.19   Med: -80.82   Max: 237.87
Current: -225.35


During the past 13 years, the highest OCF Margin % of CytomX Therapeutics was 237.87%. The lowest was -522.19%. And the median was -80.82%.

CTMX's OCF Margin % is ranked worse than
62.81% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs CTMX: -225.35


CytomX Therapeutics OCF Margin % Related Terms


CytomX Therapeutics OCF Margin % Historical Data

* Premium members only.

The historical data trend for CytomX Therapeutics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CytomX Therapeutics OCF Margin % Chart

CytomX Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -319.02 -208.39 -55.36 -62.44 -99.19

CytomX Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -41.33 -84.43 -260.74 -3,505.73 -249.06

CTMX vs SMNR, AURA, OMER: OCF Margin % Comparison

For the Biotechnology subindustry, CytomX Therapeutics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CytomX Therapeutics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CytomX Therapeutics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where CytomX Therapeutics's OCF Margin % falls into.


CTMX
36GF Score
CytomX Therapeutics Inc CTMX
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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CytomX Therapeutics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

CytomX Therapeutics's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-75.587/76.201
=-99.19 %

CytomX Therapeutics's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-25.549/10.258
=-249.06 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -249.06% mean?
CytomX Therapeutics (CTMX) has a OCF Margin % of -249.06% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on CytomX Therapeutics and its competitors. According to the industry distribution chart, CytomX Therapeutics ranks #603 out of 960 companies in the Biotechnology industry, placing it in the top 62.8%.
Is CytomX Therapeutics' OCF Margin % too high?
CytomX Therapeutics' current OCF Margin % is -249.06%. Based on the distribution chart, CytomX Therapeutics ranks #603 out of 960 companies in the Biotechnology industry, which is below the industry midpoint. Overall, CytomX Therapeutics has a GF Score™ of 36/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CytomX Therapeutics' OCF Margin % compare to SMNR and AURA?
According to the Biotechnology industry distribution chart, CytomX Therapeutics ranks #603 out of 960 companies for OCF Margin %. This places CytomX Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on CytomX Therapeutics and its competitors. CytomX Therapeutics's current OCF Margin % is -249.06%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CytomX Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, CytomX Therapeutics (CTMX) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.28, compared to a current price of $3.26 — trading 1062.5% above its estimated fair value. The current OCF Margin % is -249.06%. CytomX Therapeutics' overall GF Score™ is 36/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For CytomX Therapeutics (CTMX), the current OCF Margin % is -249.06% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CytomX Therapeutics (CTMX) Overvalued in 2026?

Based on GuruFocus' analysis, CytomX Therapeutics stock appears to be overvalued. The current stock price of $3.26 is trading 1062.5% above its estimated GF Value™ of $0.28. GuruFocus considers CytomX Therapeutics to be Significantly Overvalued.

Key valuation signals for CTMX:

  • OCF Margin %: -249.06%
  • GF Value™: $0.28 vs. price of $3.26 (1062.5% above fair value)
  • GF Score™: 36/100 with 4 warning signs

No single metric tells the full story. See the CTMX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CytomX Therapeutics Business Description

Other Exchanges 6C1:Germany
Address 151 Oyster Point Boulevard, Suite 400, South San Francisco, CA, USA, 94080
CytomX Therapeutics Inc a clinical-stage, oncology-focused biopharmaceutical company developing novel, masked, conditionally activated biologics designed to be localized to the tumor microenvironment. It is engaged in developing antibody therapeutics based on probody technology platforms. The company's probody technology platform creates proprietary cancer immunotherapies against clinically-validated targets and develops cancer therapeutics. Probody therapeutics are designed to take advantage of conditions in the tumor microenvironment to enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues.
36GF Score

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OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$3.26
Price
$0.28
GF Value