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IlluminaMEX:ILMN -4.53%57 EV-to-OCF is 28.51 as of Aug. 01, 2026, which is 29% below its 10-year median of 40.28. GuruFocus rates MEX:ILMN with a GF Score™ of 57/100 and a GF Value™ of MXN2,165.86 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 213 Medical Diagnostics & Research companies, Illumina ranks worse than 83.57% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Illumina's Enterprise Value is MXN561,958 Mil.
Illumina's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was MXN19,708 Mil. Therefore, Illumina's EV-to-OCF for today is 28.51.
The historical rank and industry rank for Illumina's EV-to-OCF or its related term are showing as below:
MEX:ILMN'
s EV-to-OCF Range Over the Past 10 Years
Min: 12.69 Med: 40.28 Max: 161.99
Current: 29.58
During the past 13 years, the highest EV-to-OCF of Illumina was 161.99. The lowest was 12.69. And the median was 40.28.
MEX:ILMN's EV-to-OCF is ranked worse than 83.57% of 213
companies
in the Medical Diagnostics & Research industry
Industry Median: 6.26
vs MEX:ILMN: 29.58
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Illumina's share price for today is MXN3375.00.
Illumina's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN96.064.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Illumina EV-to-OCF Related Terms
Illumina EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Illumina's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, Illumina's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Illumina EV-to-OCF vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Illumina's EV-to-OCF falls into.
Illumina's current Enterprise Value is MXN561,958 Mil.
Illumina's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN19,708 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Illumina (MEX:ILMN) has a EV-to-OCF of 28.51 as of Aug. 01, 2026. This is 29% below median its historical median of 40.28. Over the past decade, Illumina's EV-to-OCF has ranged from 12.69 to 161.99. According to the industry distribution chart, Illumina ranks #178 out of 213 companies in the Medical Diagnostics & Research industry, placing it in the top 83.6%.
Is Illumina's EV-to-OCF too high?
Illumina's current EV-to-OCF of 28.51 is 29% below median its 10-year median of 40.28. Over the past 10 years, this metric has ranged from a low of 12.69 to a high of 161.99. The Medical Diagnostics & Research industry median EV-to-OCF is 6.26. Illumina's value of 28.51 is 355.4% above this industry median. Based on the distribution chart, Illumina ranks #178 out of 213 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Illumina has a GF Score™ of 57/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's EV-to-OCF compare to MTD and DGX?
According to the Medical Diagnostics & Research industry distribution chart, Illumina ranks #178 out of 213 companies for EV-to-OCF. This places Illumina in the lower half of its industry. The industry median EV-to-OCF is 6.26. Illumina's value of 28.51 is 355.4% above this benchmark. Historically, Illumina's own EV-to-OCF has ranged from 12.69 to 161.99 over the past decade. While the company's 10-year median is 40.28 vs. the industry median of 6.26, Illumina has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Medical Diagnostics & Research company?
The median EV-to-OCF among Medical Diagnostics & Research companies is 6.26, based on 213 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-OCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Illumina's current EV-to-OCF of 28.51 is 355.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. For the Medical Diagnostics & Research industry, the median EV-to-OCF is 6.26 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Illumina's current EV-to-OCF is 28.51, which is 29% below median its own 10-year median of 40.28. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (MEX:ILMN) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN2,165.86, compared to a current price of MXN3,375.00 — trading 55.8% above its estimated fair value. The current EV-to-OCF is 28.51, which is 29% below median its 10-year median of 40.28 and 355.4% above the Medical Diagnostics & Research industry median of 6.26. Illumina's overall GF Score™ is 57/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Illumina (MEX:ILMN), the current EV-to-OCF is 28.51 as of Aug. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Illumina (MEX:ILMN) Overvalued in 2026?
Based on GuruFocus' analysis, Illumina stock appears to be overvalued.
The current stock price of MXN3,375.00 is trading 55.8% above its estimated GF Value™ of MXN2,165.86.
GuruFocus considers Illumina to be Significantly Overvalued.
Key valuation signals for MEX:ILMN:
EV-to-OCF: 28.51 (29% below median its 10-year median of 40.28)
GF Value™: MXN2,165.86 vs. price of MXN3,375.00 (55.8% above fair value)
Industry Position: 355.4% above the Medical Diagnostics & Research median (#178 of 213)
No single metric tells the full story. See the MEX:ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
57GF Score
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