Illumina (MEX:ILMN) Owner Earnings per Share (TTM): 92.59 (As of Jun. 2026) — 57% Above Median

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MEX:ILMN Illumina Inc MEX:ILMN
57 GF Score
Price MXN3,375.00
GF Value MXN2,165.86
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Illumina Owner Earnings per Share (TTM)?

Illumina MEX:ILMN -4.53% 57 Owner Earnings per Share (TTM) is 92.59 as of Jun. 2026, which is 57% above its 10-year median of 59.00. GuruFocus rates MEX:ILMN with a GF Score™ of 57/100 and a GF Value™ of MXN2,165.86 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 75 Medical Diagnostics & Research companies, Illumina ranks worse than 64% on this metric.

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

Illumina's Owner Earnings per Share (TTM) ended in Jun. 2026 was MXN92.59. It's Price-to-Owner-Earnings ratio for today is 36.45.


The historical rank and industry rank for Illumina's Owner Earnings per Share (TTM) or its related term are showing as below:

MEX:ILMN' s Price-to-Owner-Earnings Range Over the Past 10 Years
Min: 16.92   Med: 59   Max: 134.26
Current: 36.45


During the past 13 years, the highest Price-to-Owner-Earnings ratio of Illumina was 134.26. The lowest was 16.92. And the median was 59.00.


MEX:ILMN's Price-to-Owner-Earnings is ranked worse than
64% of 75 companies
in the Medical Diagnostics & Research industry
Industry Median: 27.11 vs MEX:ILMN: 36.45

Illumina's Earnings per Share (Diluted) for the three months ended in Jun. 2026 was MXN23.56. Its Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was MXN96.06. It's PE Ratio (TTM) ratio for today is 35.13.

Illumina's EPS without NRI for the three months ended in Jun. 2026 was MXN23.56. Its EPS without NRI for the trailing twelve months (TTM) ended in Jun. 2026 was MXN93.06. It's PE Ratio without NRI ratio for today is 36.27.


Be Aware

Assumption: Companies usually do not report maintenance capital expenditures and growth capital expenditures separately. Here we use estimated numbers and average them over 5 years. The method to estimate maintenance capital expenditures can be found in above part 4.

Note: GuruFocus' Change In Working Capital is provided by Morningstar. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And it includes non-current parts of assets and liabilities.


Illumina Owner Earnings per Share (TTM) Related Terms


Illumina Owner Earnings per Share (TTM) Historical Data

* Premium members only.

The historical data trend for Illumina's Owner Earnings per Share (TTM) can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Illumina Owner Earnings per Share (TTM) Chart

Illumina Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Owner Earnings per Share (TTM)
Get a 7-Day Free Trial Premium Member Only Premium Member Only 76.47 -469.08 -111.81 -215.29 109.70

Illumina Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Owner Earnings per Share (TTM) Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 97.66 99.16 109.70 105.92 89.61

MEX:ILMN vs MTD, DGX, LH: Owner Earnings per Share (TTM) Comparison

For the Diagnostics & Research subindustry, Illumina's Price-to-Owner-Earnings, along with its competitors' market caps and Price-to-Owner-Earnings data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Illumina Price-to-Owner-Earnings vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's Price-to-Owner-Earnings distribution charts can be found below:

* The bar in red indicates where Illumina's Price-to-Owner-Earnings falls into.


MEX:ILMN
57GF Score
Illumina Inc MEX:ILMN
Owner Earnings per Share (TTM) is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Illumina Owner Earnings per Share (TTM) Calculation

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume. (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

To make it simple, then you will have:

Owner Earnings per Share (TTM) = (Net Income + Depreciation, Depletion and Amortization + Change In Deferred Tax - 5Y Average of Maintenance Capital Expenditure + Change In Working Capital) / Shares Outstanding (Diluted Average)

Illumina's Owner Earnings per Share (TTM) Calculation:

TTM / Last Quarter Average of Last 20 Quarters
Net Income 14,794
Depreciation, Depletion and Amortization 3,662
Change In Deferred Tax 1,364
5Y Average of Maintenance Capital Expenditure 3,201
Change In Working Capital -1,369
Shares Outstanding (Diluted Average) 153

1. Start with "Net Income" from income statement. Illumina's Net Income for the trailing twelve months (TTM) ended in Jun. 2026 was MXN14,794 Mil.

2. "Depreciation, Depletion and Amortization" is from cashflow statement. Illumina's Depreciation, Depletion and Amortization for the trailing twelve months (TTM) ended in Jun. 2026 was MXN3,662 Mil. This needs to be added back because company does not actually need to pay cash for it. It is a non-cash item.

3. Other non-cash charges usually include "Stock Based Compensation" and "Change In Deferred Tax":
However, to be conservative, GuruFocus will not add Stock Based Compensation back to net income. Illumina's Change In Deferred Tax for the trailing twelve months (TTM) ended in Jun. 2026 was MXN1,364 Mil.

4. Average maintenance capital expenditure over a business/industry cycle: 5-Year Average Maintenance Capital Expenditure = MXN3,201 Mil

It is usually best to take a long-term average of maintenance capital expenditure. Ideally this would be as long as 10 years and include at least one economic downturn. However, since many companies do not have as long as 10-year history, here GuruFocus uses the latest 5 years data to do the calculation. To smooth out unusual years but reflect recent developments, we take an average of the 5 year maintenance capital expenditure.

The following shows how to get maintenance capital expenditure.

First, calculate the revenue change regarding to the previous quarter. If the revenue decreased from the previous quarter, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
Second, if the revenue increased from the previous quarter, then calculate the percentage of Net PPE as of corresponding Revenue.
Growth Capital Expenditure = Percentage of Property, Plant and Equipment as of corresponding Revenue * Revenue Increase
Third, calculate Capital Expenditure (positive) - Growth Capital Expenditure.
If [Capital Expenditure (positive) - Growth Capital Expenditure] was negative, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
If [Capital Expenditure (positive) - Growth Capital Expenditure] was positive, then the Maintenance Capital Expenditure = Capital Expenditure (positive) - Growth Capital Expenditure.
Fourth, get the average of the 5 years maintenance capital expenditure.

Illumina's 5-Year Average Maintenance Capital Expenditure = MXN3,201 Mil

5. "Change In Working Capital" is from cashflow statement. Illumina's Change In Working Capital for the trailing twelve months (TTM) ended in Jun. 2026 was MXN-1,369 Mil.
Note: GuruFocus' Change in Working Capital is provided by Morningstar. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And sometimes it includes non-current parts of assets and liabilities.

6. Illumina's Shares Outstanding (Diluted Average) for the months ended in Jun. 2026 was 153.000 Mil.

Illumina's Onwer Earnings Per Share for Jun. 2026 is calculated as:

Owner Earnings per Share (TTM)
=( Net Income+Depreciation, Depletion and Amortization+Change In Deferred Tax
=( 14793.859 +3661.693+1364.225
-5Y Avg of Maintenance CAPEX+Change In Working Capital )/Shares Outstanding (Diluted Average)
-3201.102701101+-1369.411)/153.000
=92.59

Price-to-Owner-Earnings=Current Price/Owner Earnings per Share (TTM)
=3375.00/92.59
=36.45

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Owner Earnings per Share (TTM) of 92.59 mean?
Illumina (MEX:ILMN) has a Owner Earnings per Share (TTM) of 92.59 as of Jun. 2026. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Illumina. This is 57% above median its historical median of 59.00. Over the past decade, Illumina's Owner Earnings per Share (TTM) has ranged from 16.92 to 134.26. According to the industry distribution chart, Illumina ranks #48 out of 75 companies in the Medical Diagnostics & Research industry, placing it in the top 64%.
Is Illumina's Owner Earnings per Share (TTM) too high?
Illumina's current Owner Earnings per Share (TTM) of 92.59 is 57% above median its 10-year median of 59.00. Over the past 10 years, this metric has ranged from a low of 16.92 to a high of 134.26. The Medical Diagnostics & Research industry median Owner Earnings per Share (TTM) is 27.11. Illumina's value of 92.59 is 241.5% above this industry median. Based on the distribution chart, Illumina ranks #48 out of 75 companies in the Medical Diagnostics & Research industry, which is below the industry midpoint. Overall, Illumina has a GF Score™ of 57/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's Owner Earnings per Share (TTM) compare to MTD and DGX?
According to the Medical Diagnostics & Research industry distribution chart, Illumina ranks #48 out of 75 companies for Owner Earnings per Share (TTM). This places Illumina in the lower half of its industry. The industry median Owner Earnings per Share (TTM) is 27.11. Illumina's value of 92.59 is 241.5% above this benchmark. Historically, Illumina's own Owner Earnings per Share (TTM) has ranged from 16.92 to 134.26 over the past decade. While the company's 10-year median is 59.00 vs. the industry median of 27.11, Illumina has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Owner Earnings per Share (TTM) for a Medical Diagnostics & Research company?
The median Owner Earnings per Share (TTM) among Medical Diagnostics & Research companies is 27.11, based on 75 companies in the industry. Companies in the top quartile (top 25%) have a Owner Earnings per Share (TTM) significantly above this median, while those in the bottom quartile fall well below. However, Owner Earnings per Share (TTM) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Illumina's current Owner Earnings per Share (TTM) of 92.59 is 241.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Owner Earnings per Share (TTM) mean?
A high Owner Earnings per Share (TTM) can signal that a stock is expensive relative to its fundamentals. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Illumina. For the Medical Diagnostics & Research industry, the median Owner Earnings per Share (TTM) is 27.11 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Illumina's current Owner Earnings per Share (TTM) is 92.59, which is 57% above median its own 10-year median of 59.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (MEX:ILMN) is currently considered Significantly Overvalued. The stock's GF Value™ is MXN2,165.86, compared to a current price of MXN3,375.00 — trading 55.8% above its estimated fair value. The current Owner Earnings per Share (TTM) is 92.59, which is 57% above median its 10-year median of 59.00 and 241.5% above the Medical Diagnostics & Research industry median of 27.11. Illumina's overall GF Score™ is 57/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Owner Earnings per Share (TTM) calculated?
Owner Earnings per Share (TTM) is calculated from a company's financial statements. For Illumina (MEX:ILMN), the current Owner Earnings per Share (TTM) is 92.59 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Illumina (MEX:ILMN) Overvalued in 2026?

Based on GuruFocus' analysis, Illumina stock appears to be overvalued. The current stock price of MXN3,375.00 is trading 55.8% above its estimated GF Value™ of MXN2,165.86. GuruFocus considers Illumina to be Significantly Overvalued.

Key valuation signals for MEX:ILMN:

  • Owner Earnings per Share (TTM): 92.59 (57% above median its 10-year median of 59.00)
  • GF Value™: MXN2,165.86 vs. price of MXN3,375.00 (55.8% above fair value)
  • GF Score™: 57/100 with 7 warning signs
  • Industry Position: 241.5% above the Medical Diagnostics & Research median (#48 of 75)

No single metric tells the full story. See the MEX:ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Illumina Business Description

Address 5200 Illumina Way, San Diego, CA, USA, 92122
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
57GF Score

Get the complete analysis for MEX:ILMN

Owner Earnings per Share (TTM) is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN3,375.00
Price
MXN2,165.86
GF Value