WAVE Life Sciences (FRA:1U5) Enterprise Value: €593.22 Mil (As of Jul. 03, 2026) ***


FRA:1U5 WAVE Life Sciences Ltd FRA:1U5
59 GF Score
Price €4.82
GF Value €3.40
Valuation Significantly Overvalued
! 2 Warning Signs
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What is WAVE Life Sciences Enterprise Value?

WAVE Life Sciences FRA:1U5 +1.26% 59 Enterprise Value is €593.22 Mil as of Jul. 03, 2026. GuruFocus rates FRA:1U5 with a GF Score™ of 59/100 and a GF Value™ of €3.40 (Significantly Overvalued). The stock has 2 warning signs investors should review.

Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, WAVE Life Sciences's Enterprise Value is €593.22 Mil. WAVE Life Sciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was €-169.05 Mil. Therefore, WAVE Life Sciences's EV-to-EBIT ratio for today is -3.51.

EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, WAVE Life Sciences's Enterprise Value is €593.22 Mil. WAVE Life Sciences's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was €-161.32 Mil. Therefore, WAVE Life Sciences's EV-to-EBITDA ratio for today is -3.68.

EV-to-Revenue is calculated as Enterprise Value divided by its Revenue. As of today, WAVE Life Sciences's Enterprise Value is €593.22 Mil. WAVE Life Sciences's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 was €61.83 Mil. Therefore, WAVE Life Sciences's EV-to-Revenue ratio for today is 9.59.

EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations. As of today, WAVE Life Sciences's Enterprise Value is €593.22 Mil. WAVE Life Sciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was €-158.31 Mil. Therefore, WAVE Life Sciences's EV-to-OCF ratio for today is -3.75.

EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow. As of today, WAVE Life Sciences's Enterprise Value is €593.22 Mil. WAVE Life Sciences's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was €-159.16 Mil. Therefore, WAVE Life Sciences's EV-to-FCF ratio for today is -3.73.

*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.


WAVE Life Sciences  (FRA:1U5) Enterprise Value Explanation

When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.

If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.

The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.

For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.

Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.

1. EV-to-EBIT is calculated as Enterprise Value divided by its EBIT.

WAVE Life Sciences's EV-to-EBIT for today is

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=593.222/-169.051
=-3.51

WAVE Life Sciences's current Enterprise Value is €593.22 Mil.
WAVE Life Sciences's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-169.05 Mil.

2. EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA.

WAVE Life Sciences's EV-to-EBITDA for today is:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA(TTM)
=593.222/-161.321
=-3.68

WAVE Life Sciences's current Enterprise Value is €593.22 Mil.
WAVE Life Sciences's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-161.32 Mil.

3. EV-to-Revenue is calculated as Enterprise Value divided by its Revenue.

WAVE Life Sciences's EV-to-Revenue for today is:

EV-to-Revenue=Enterprise Value (Today)/Revenue (TTM)
=593.222/61.834
=9.59

WAVE Life Sciences's current Enterprise Value is €593.22 Mil.
WAVE Life Sciences's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €61.83 Mil.

4. EV-to-OCF is calculated as Enterprise Value divided by its Cash Flow from Operations.

WAVE Life Sciences's EV-to-OCF for today is:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=593.222/-158.305
=-3.75

WAVE Life Sciences's current Enterprise Value is €593.22 Mil.
WAVE Life Sciences's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-158.31 Mil.

5. EV-to-FCF is calculated as Enterprise Value divided by its Free Cash Flow.

WAVE Life Sciences's EV-to-FCF for today is:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=593.222/-159.159
=-3.73

WAVE Life Sciences's current Enterprise Value is €593.22 Mil.
WAVE Life Sciences's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €-159.16 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


WAVE Life Sciences Enterprise Value Related Terms


WAVE Life Sciences Enterprise Value Historical Data

* Premium members only.

The historical data trend for WAVE Life Sciences's Enterprise Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

WAVE Life Sciences Enterprise Value Chart

WAVE Life Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Enterprise Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only 53.12 503.07 386.73 1,602.83 2,278.37

WAVE Life Sciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Enterprise Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 975.80 678.70 771.32 2,278.37 600.38

FRA:1U5 vs CGEM, LXRX, XNCR: Enterprise Value Comparison

For the Biotechnology subindustry, WAVE Life Sciences's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


WAVE Life Sciences Enterprise Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, WAVE Life Sciences's Enterprise Value distribution charts can be found below:

* The bar in red indicates where WAVE Life Sciences's Enterprise Value falls into.


FRA:1U5
59GF Score
WAVE Life Sciences Ltd FRA:1U5
Enterprise Value is just one metric. See GF Score™, valuation, warning signs, and more.
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WAVE Life Sciences Enterprise Value Calculation

Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.

WAVE Life Sciences's Enterprise Value for the fiscal year that ended in Dec. 2025 is calculated as

WAVE Life Sciences's Enterprise Value for the quarter that ended in Mar. 2026 is calculated as

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Enterprise Value →
What does a Enterprise Value of €593.22 Mil mean?
WAVE Life Sciences (FRA:1U5) has a Enterprise Value of €593.22 Mil as of Jul. 03, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on WAVE Life Sciences and its competitors.
Is WAVE Life Sciences' Enterprise Value too high?
WAVE Life Sciences' current Enterprise Value is €593.22 Mil. Overall, WAVE Life Sciences has a GF Score™ of 59/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does WAVE Life Sciences' Enterprise Value compare to CGEM and LXRX?
WAVE Life Sciences' Enterprise Value of €593.22 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on WAVE Life Sciences and its competitors. WAVE Life Sciences's current Enterprise Value is €593.22 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is WAVE Life Sciences stock overvalued right now?
Based on GuruFocus' analysis, WAVE Life Sciences (FRA:1U5) is currently considered Significantly Overvalued. The stock's GF Value™ is €3.40, compared to a current price of €4.82 — trading 41.8% above its estimated fair value. The current Enterprise Value is €593.22 Mil. WAVE Life Sciences' overall GF Score™ is 59/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For WAVE Life Sciences (FRA:1U5), the current Enterprise Value is €593.22 Mil as of Jul. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is WAVE Life Sciences (FRA:1U5) Overvalued in 2026?

Based on GuruFocus' analysis, WAVE Life Sciences stock appears to be overvalued. The current stock price of €4.82 is trading 41.8% above its estimated GF Value™ of €3.40. GuruFocus considers WAVE Life Sciences to be Significantly Overvalued.

Key valuation signals for FRA:1U5:

  • Enterprise Value: €593.22 Mil
  • GF Value™: €3.40 vs. price of €4.82 (41.8% above fair value)
  • GF Score™: 59/100 with 2 warning signs

No single metric tells the full story. See the FRA:1U5 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


WAVE Life Sciences Business Description

Other Exchanges WVE:USA1U5:Germany
Address 7 Straits View No. 12-00, Marina One East Tower, Singapore, SGP, 018936
WAVE Life Sciences Ltd is a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines also known as oligonucleotides, targeting ribonucleic acid (RNA), to transform human health. RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Its toolkit of RNA-targeting modalities includes RNA editing, antisense silencing, and RNA interference, providing capabilities for designing and sustainably delivering candidates that optimally address disease biology. Its programs are for rare and prevalent diseases, including alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington's disease.
59GF Score

Get the complete analysis for FRA:1U5

Enterprise Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.82
Price
€3.40
GF Value