WAVE Life Sciences (FRA:1U5) OCF Yield %: -15.28 (As of Jul. 04, 2026)


FRA:1U5 WAVE Life Sciences Ltd FRA:1U5
59 GF Score
Price €5.40
GF Value €3.80
Valuation Significantly Overvalued
! 2 Warning Signs
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What is WAVE Life Sciences OCF Yield %?

WAVE Life Sciences FRA:1U5 +12.03% 59 OCF Yield % is -15.28 as of Jul. 04, 2026. GuruFocus rates FRA:1U5 with a GF Score™ of 59/100 and a GF Value™ of €3.80 (Significantly Overvalued). The stock has 2 warning signs investors should review. Among 1,414 Biotechnology companies, WAVE Life Sciences ranks worse than 63.44% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, WAVE Life Sciences's Trailing 12-Month Cash Flow from Operations is €-158.31 Mil, and Market Cap is €1,057.64 Mil. Therefore, WAVE Life Sciences's OCF Yield % for today is -15.28%.

The historical rank and industry rank for WAVE Life Sciences's OCF Yield % or its related term are showing as below:

FRA:1U5' s OCF Yield % Range Over the Past 10 Years
Min: -113.51   Med: -13.59   Max: -0.46
Current: -15.28


During the past 13 years, the highest OCF Yield % of WAVE Life Sciences was -0.46%. The lowest was -113.51%. And the median was -13.59%.

FRA:1U5's OCF Yield % is ranked worse than
63.44% of 1414 companies
in the Biotechnology industry
Industry Median: -8.155 vs FRA:1U5: -15.28

WAVE Life Sciences's OCF Margin % for the quarter that ended in Mar. 2026 was %.


WAVE Life Sciences OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


WAVE Life Sciences OCF Yield % Related Terms


WAVE Life Sciences OCF Yield % Historical Data

* Premium members only.

The historical data trend for WAVE Life Sciences's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

WAVE Life Sciences OCF Yield % Chart

WAVE Life Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -49.26 -21.89 -3.29 -7.73 -5.77

WAVE Life Sciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -19.79 -18.98 -16.52 -4.15 -19.48

FRA:1U5 vs CGEM, LXRX, XNCR: OCF Yield % Comparison

For the Biotechnology subindustry, WAVE Life Sciences's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


WAVE Life Sciences OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, WAVE Life Sciences's OCF Yield % distribution charts can be found below:

* The bar in red indicates where WAVE Life Sciences's OCF Yield % falls into.


FRA:1U5
59GF Score
WAVE Life Sciences Ltd FRA:1U5
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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WAVE Life Sciences OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

WAVE Life Sciences's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-160.119 / 2777.368
=-5.77%

WAVE Life Sciences's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-51.513 * 4 / 1057.859
=-19.48%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -15.28 mean?
WAVE Life Sciences (FRA:1U5) has a OCF Yield % of -15.28 as of Jul. 04, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on WAVE Life Sciences and its competitors. According to the industry distribution chart, WAVE Life Sciences ranks #897 out of 1414 companies in the Biotechnology industry, placing it in the top 63.4%.
Is WAVE Life Sciences' OCF Yield % too high?
WAVE Life Sciences' current OCF Yield % is -15.28. Based on the distribution chart, WAVE Life Sciences ranks #897 out of 1414 companies in the Biotechnology industry, which is below the industry midpoint. Overall, WAVE Life Sciences has a GF Score™ of 59/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does WAVE Life Sciences' OCF Yield % compare to CGEM and LXRX?
According to the Biotechnology industry distribution chart, WAVE Life Sciences ranks #897 out of 1414 companies for OCF Yield %. This places WAVE Life Sciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on WAVE Life Sciences and its competitors. WAVE Life Sciences's current OCF Yield % is -15.28. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is WAVE Life Sciences stock overvalued right now?
Based on GuruFocus' analysis, WAVE Life Sciences (FRA:1U5) is currently considered Significantly Overvalued. The stock's GF Value™ is €3.80, compared to a current price of €5.40 — trading 42.1% above its estimated fair value. The current OCF Yield % is -15.28. WAVE Life Sciences' overall GF Score™ is 59/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For WAVE Life Sciences (FRA:1U5), the current OCF Yield % is -15.28 as of Jul. 04, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is WAVE Life Sciences (FRA:1U5) Overvalued in 2026?

Based on GuruFocus' analysis, WAVE Life Sciences stock appears to be overvalued. The current stock price of €5.40 is trading 42.1% above its estimated GF Value™ of €3.80. GuruFocus considers WAVE Life Sciences to be Significantly Overvalued.

Key valuation signals for FRA:1U5:

  • OCF Yield %: -15.28
  • GF Value™: €3.80 vs. price of €5.40 (42.1% above fair value)
  • GF Score™: 59/100 with 2 warning signs

No single metric tells the full story. See the FRA:1U5 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


WAVE Life Sciences Business Description

Other Exchanges WVE:USA1U5:Germany
Address 7 Straits View No. 12-00, Marina One East Tower, Singapore, SGP, 018936
WAVE Life Sciences Ltd is a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines also known as oligonucleotides, targeting ribonucleic acid (RNA), to transform human health. RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Its toolkit of RNA-targeting modalities includes RNA editing, antisense silencing, and RNA interference, providing capabilities for designing and sustainably delivering candidates that optimally address disease biology. Its programs are for rare and prevalent diseases, including alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington's disease.
59GF Score

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OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€5.40
Price
€3.80
GF Value