SION (Sionna Therapeutics) EPS without NRI: $-1.93 (TTM As of Mar. 2026)


SION Sionna Therapeutics Inc SION
12 GF Score
Price $43.99
! 3 Warning Signs
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What is Sionna Therapeutics EPS without NRI?

Sionna Therapeutics SION +5.64% 12 EPS without NRI is $-1.93 as of Mar. 2026. GuruFocus rates SION with a GF Score™ of 12/100. The stock has 3 warning signs investors should review. Among 1,170 Biotechnology companies, Sionna Therapeutics ranks worse than 62.22% on this metric.

Sionna Therapeutics's earnings per share without non-recurring items for the three months ended in Mar. 2026 was $-0.60. Its earnings per share without non-recurring items for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.93.

During the past 3 years, the average earnings per share (NRI) Growth Rate was 6.80% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EPS without NRI Growth Rate using Earnings per share without Non-Recurring Items (NRI) data.

The historical rank and industry rank for Sionna Therapeutics's EPS without NRI or its related term are showing as below:

SION' s 3-Year EPS without NRI Growth Rate Range Over the Past 10 Years
Min: 6.8   Med: 6.8   Max: 6.8
Current: 6.8

During the past 4 years, Sionna Therapeutics's highest 3-Year average Earnings Per Share (NRI) Growth Rate was 6.80% per year. The lowest was 6.80% per year. And the median was 6.80% per year.

SION's 3-Year EPS without NRI Growth Rate is ranked worse than
62.22% of 1170 companies
in the Biotechnology industry
Industry Median: 16.75 vs SION: 6.80

Sionna Therapeutics's EPS (Diluted) for the three months ended in Mar. 2026 was $-0.60. Its EPS (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.93.

Sionna Therapeutics's EPS (Basic) for the three months ended in Mar. 2026 was $-0.60. Its EPS (Basic) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.93.


Sionna Therapeutics  (NAS:SION) EPS without NRI Explanation

EPS without NRI removes onetime and unusual items from EPS, to provide investors with a more accurate measure of the company’s true earnings. The earnings are adjusted for items that are irregular or unusual in nature, and/or are non-recurring. This is calculated using Net Income (Continuing Operations) plus/minus any tax affected unusual Items and Goodwill Impairments/Write Offs. This can be used to fairly measure a company's profitability.


Be Aware

Compared with Earnings per share, a company's cash flow is better indicator of the company's earnings power.

If a company's earnings per share is less than cash flow per share over long term, investors need to be cautious and find out why.


Sionna Therapeutics EPS without NRI Related Terms


Sionna Therapeutics EPS without NRI Historical Data

* Premium members only.

The historical data trend for Sionna Therapeutics's EPS without NRI can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sionna Therapeutics EPS without NRI Chart

Sionna Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
EPS without NRI
-2.32 -1.70 -1.45 -1.88

Sionna Therapeutics Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EPS without NRI Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only -0.62 -0.41 -0.46 -0.46 -0.60

SION vs TYRA, RAPP, IOVA: EPS without NRI Comparison

For the Biotechnology subindustry, Sionna Therapeutics's PE Ratio without NRI, along with its competitors' market caps and PE Ratio without NRI data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Sionna Therapeutics PE Ratio without NRI vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Sionna Therapeutics's PE Ratio without NRI distribution charts can be found below:

* The bar in red indicates where Sionna Therapeutics's PE Ratio without NRI falls into.


SION
12GF Score
Sionna Therapeutics Inc SION
EPS without NRI is just one metric. See GF Score™, valuation, warning signs, and more.
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Sionna Therapeutics EPS without NRI Calculation

Earnings Per Share (EPS) is the single most important variable used by Wall Street in determining the earnings power of a company. But investors need to be aware that Earnings per Share can be easily manipulated by adjusting depreciation and amortization rate or non-recurring items. That's why GuruFocus lists EPS without NRI, which better reflects the company's underlying performance.

Earnings Per Share without Non-Recurring Items is the amount of earnings without non-recurring items per outstanding share of the company's stock.

EPS without NRI for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.93

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EPS without NRI →
What does a EPS without NRI of $-1.93 mean?
Sionna Therapeutics (SION) has a EPS without NRI of $-1.93 as of Mar. 2026. EPS without NRI represents per-share earnings excluding one-time charges. View historical data on Sionna Therapeutics and its competitors. According to the industry distribution chart, Sionna Therapeutics ranks #728 out of 1170 companies in the Biotechnology industry, placing it in the top 62.2%.
Is Sionna Therapeutics' EPS without NRI too high?
Sionna Therapeutics' current EPS without NRI is $-1.93. Based on the distribution chart, Sionna Therapeutics ranks #728 out of 1170 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Sionna Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Sionna Therapeutics' EPS without NRI compare to TYRA and RAPP?
According to the Biotechnology industry distribution chart, Sionna Therapeutics ranks #728 out of 1170 companies for EPS without NRI. This places Sionna Therapeutics in the lower half of its industry. The industry median EPS without NRI is 16.75. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EPS without NRI for a Biotechnology company?
The median EPS without NRI among Biotechnology companies is 16.75, based on 1,170 companies in the industry. Companies in the top quartile (top 25%) have a EPS without NRI significantly above this median, while those in the bottom quartile fall well below. However, EPS without NRI should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EPS without NRI mean?
A high EPS without NRI can signal that a stock is expensive relative to its fundamentals. EPS without NRI represents per-share earnings excluding one-time charges. View historical data on Sionna Therapeutics and its competitors. For the Biotechnology industry, the median EPS without NRI is 16.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sionna Therapeutics's current EPS without NRI is $-1.93. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sionna Therapeutics stock overvalued right now?
Sionna Therapeutics (SION) has a current EPS without NRI of $-1.93. The current EPS without NRI is $-1.93. Sionna Therapeutics' overall GF Score™ is 12/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EPS without NRI calculated?
EPS without NRI is calculated from a company's financial statements. For Sionna Therapeutics (SION), the current EPS without NRI is $-1.93 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Sionna Therapeutics Business Description

Address 21 Hickory Drive, Suite 500, Waltham, MA, USA, 02451
Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefits to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
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