SION (Sionna Therapeutics) OCF Yield %: -29.05 (As of Aug. 18, 2026)

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SION Sionna Therapeutics Inc SION
12 GF Score
Price $5.78
! 2 Warning Signs
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What is Sionna Therapeutics OCF Yield %?

Sionna Therapeutics SION -2.20% 12 OCF Yield % is -29.05 as of Aug. 18, 2026. GuruFocus rates SION with a GF Score™ of 12/100. The stock has 2 warning signs investors should review. Among 1,410 Biotechnology companies, Sionna Therapeutics ranks worse than 75.53% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Sionna Therapeutics's Trailing 12-Month Cash Flow from Operations is $-75.92 Mil, and Market Cap is $261.33 Mil. Therefore, Sionna Therapeutics's OCF Yield % for today is -29.05%.

The historical rank and industry rank for Sionna Therapeutics's OCF Yield % or its related term are showing as below:

SION' s OCF Yield % Range Over the Past 10 Years
Min: -29.77   Med: 0   Max: -28.19
Current: -29.05


During the past 4 years, the highest OCF Yield % of Sionna Therapeutics was -28.19%. The lowest was -29.77%. And the median was %.

SION's OCF Yield % is ranked worse than
75.53% of 1410 companies
in the Biotechnology industry
Industry Median: -8.37 vs SION: -29.05

Sionna Therapeutics's OCF Margin % for the quarter that ended in Jun. 2026 was %.


Sionna Therapeutics OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Sionna Therapeutics OCF Yield % Related Terms


Sionna Therapeutics OCF Yield % Historical Data

* Premium members only.

The historical data trend for Sionna Therapeutics's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sionna Therapeutics OCF Yield % Chart

Sionna Therapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
OCF Yield %
0.00 0.00 0.00 -3.60

Sionna Therapeutics Quarterly Data
Dec22 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only -9.48 -4.66 -3.61 -4.83 -4.47

SION vs HRMY, VRDN, URGN: OCF Yield % Comparison

For the Biotechnology subindustry, Sionna Therapeutics's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Sionna Therapeutics OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Sionna Therapeutics's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Sionna Therapeutics's OCF Yield % falls into.


SION
12GF Score
Sionna Therapeutics Inc SION
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Sionna Therapeutics OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Sionna Therapeutics's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-66.297 / 1839.94536
=-3.60%

Sionna Therapeutics's annualized OCF Yield % for the quarter that ended in Jun. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-22.22 * 4 / 1986.76436
=-4.47%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -29.05 mean?
Sionna Therapeutics (SION) has a OCF Yield % of -29.05 as of Aug. 18, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Sionna Therapeutics and its competitors. According to the industry distribution chart, Sionna Therapeutics ranks #1065 out of 1410 companies in the Biotechnology industry, placing it in the top 75.5%.
Is Sionna Therapeutics' OCF Yield % too high?
Sionna Therapeutics' current OCF Yield % is -29.05. Based on the distribution chart, Sionna Therapeutics ranks #1065 out of 1410 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Sionna Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Sionna Therapeutics' OCF Yield % compare to HRMY and VRDN?
According to the Biotechnology industry distribution chart, Sionna Therapeutics ranks #1065 out of 1410 companies for OCF Yield %. This places Sionna Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Sionna Therapeutics and its competitors. Sionna Therapeutics's current OCF Yield % is -29.05. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sionna Therapeutics stock overvalued right now?
Sionna Therapeutics (SION) has a current OCF Yield % of -29.05. The current OCF Yield % is -29.05. Sionna Therapeutics' overall GF Score™ is 12/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Sionna Therapeutics (SION), the current OCF Yield % is -29.05 as of Aug. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Sionna Therapeutics Business Description

Address 21 Hickory Drive, Suite 500, Waltham, MA, USA, 02451
Sionna Therapeutics Inc is a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (CF) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein to deliver clinically meaningful benefits to CF patients. CF is a progressive and life-threatening genetic disease caused by inherited mutations in the CFTR gene, which heads to insufficient CFTR function. The Company is managed as one operating segment focused on the research and development of cystic fibrosis therapies.
12GF Score

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OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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