AMLX (Amylyx Pharmaceuticals) EV-to-FCF: -14.12 (As of Jul. 13, 2026)


AMLX Amylyx Pharmaceuticals Inc AMLX
33 GF Score
Price $17.77
! 3 Warning Signs
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What is Amylyx Pharmaceuticals EV-to-FCF?

Amylyx Pharmaceuticals AMLX -3.29% 33 EV-to-FCF is -14.12 as of Jul. 13, 2026. GuruFocus rates AMLX with a GF Score™ of 33/100. The stock has 3 warning signs investors should review. Among 562 Drug Manufacturers companies, Amylyx Pharmaceuticals ranks worse than 177935.77% on this metric.

EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, Amylyx Pharmaceuticals's Enterprise Value is $1,701.64 Mil. Amylyx Pharmaceuticals's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-120.53 Mil. Therefore, Amylyx Pharmaceuticals's EV-to-FCF for today is -14.12.

The historical rank and industry rank for Amylyx Pharmaceuticals's EV-to-FCF or its related term are showing as below:

AMLX' s EV-to-FCF Range Over the Past 10 Years
Min: -17.7   Med: -6.65   Max: 87.46
Current: -14.12

During the past 7 years, the highest EV-to-FCF of Amylyx Pharmaceuticals was 87.46. The lowest was -17.70. And the median was -6.65.

AMLX's EV-to-FCF is ranked worse than
100% of 562 companies
in the Drug Manufacturers industry
Industry Median: 20.955 vs AMLX: -14.12

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-07-13), Amylyx Pharmaceuticals's stock price is $17.77. Amylyx Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-1.500. Therefore, Amylyx Pharmaceuticals's PE Ratio (TTM) for today is At Loss.


Amylyx Pharmaceuticals  (NAS:AMLX) EV-to-FCF Explanation

EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Amylyx Pharmaceuticals's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=17.77/-1.500
=At Loss

Amylyx Pharmaceuticals's share price for today is $17.77.
Amylyx Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.500.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Amylyx Pharmaceuticals EV-to-FCF Related Terms


Amylyx Pharmaceuticals EV-to-FCF Historical Data

* Premium members only.

The historical data trend for Amylyx Pharmaceuticals's EV-to-FCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Amylyx Pharmaceuticals EV-to-FCF Chart

Amylyx Pharmaceuticals Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-FCF
Get a 7-Day Free Trial 0.00 -11.61 58.96 -0.51 -8.23

Amylyx Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-FCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.54 -2.39 -7.47 -8.23 -10.53

AMLX vs ANIP, TRLV, PBH: EV-to-FCF Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Amylyx Pharmaceuticals's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Amylyx Pharmaceuticals EV-to-FCF vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Amylyx Pharmaceuticals's EV-to-FCF distribution charts can be found below:

* The bar in red indicates where Amylyx Pharmaceuticals's EV-to-FCF falls into.


AMLX
33GF Score
Amylyx Pharmaceuticals Inc AMLX
EV-to-FCF is just one metric. See GF Score™, valuation, warning signs, and more.
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Amylyx Pharmaceuticals EV-to-FCF Calculation

Amylyx Pharmaceuticals's EV-to-FCF for today is calculated as:

EV-to-FCF=Enterprise Value (Today)/Free Cash Flow (TTM)
=1701.644/-120.528
=-14.12

Amylyx Pharmaceuticals's current Enterprise Value is $1,701.64 Mil.
Amylyx Pharmaceuticals's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-120.53 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-FCF →
What does a EV-to-FCF of -14.12 mean?
Amylyx Pharmaceuticals (AMLX) has a EV-to-FCF of -14.12 as of Jul. 13, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Amylyx Pharmaceuticals and its competitors. According to the industry distribution chart, Amylyx Pharmaceuticals ranks #999999 out of 562 companies in the Drug Manufacturers industry.
Is Amylyx Pharmaceuticals' EV-to-FCF too high?
Amylyx Pharmaceuticals' current EV-to-FCF is -14.12. Based on the distribution chart, Amylyx Pharmaceuticals ranks #999999 out of 562 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Amylyx Pharmaceuticals has a GF Score™ of 33/100, reflecting its overall financial health beyond just this single metric.
How does Amylyx Pharmaceuticals' EV-to-FCF compare to ANIP and TRLV?
According to the Drug Manufacturers industry distribution chart, Amylyx Pharmaceuticals ranks #999999 out of 562 companies for EV-to-FCF. This places Amylyx Pharmaceuticals in the lower half of its industry. The industry median EV-to-FCF is 20.96. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Drug Manufacturers company?
The median EV-to-FCF among Drug Manufacturers companies is 20.96, based on 562 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on Amylyx Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median EV-to-FCF is 20.96 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Amylyx Pharmaceuticals's current EV-to-FCF is -14.12. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Amylyx Pharmaceuticals stock overvalued right now?
Amylyx Pharmaceuticals (AMLX) has a current EV-to-FCF of -14.12. The current EV-to-FCF is -14.12. Amylyx Pharmaceuticals' overall GF Score™ is 33/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For Amylyx Pharmaceuticals (AMLX), the current EV-to-FCF is -14.12 as of Jul. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Amylyx Pharmaceuticals Business Description

Address 55 Cambridge Parkway, Suite 6W, Cambridge, MA, USA, 02142
Amylyx Pharmaceuticals Inc is a clinical-stage pharmaceutical company focused on developing novel therapies for communities with high unmet medical needs. The company has preclinical and clinical development programs in endocrine conditions and neurodegenerative diseases. Its pipeline includes investigational therapies matched with diseases based on mechanistic rationale, clinical outcomes, biomarkers, and preclinical data. The company is currently developing avexitide for Post-Bariatric Hypoglycemia, AMX0035 for Wolfram Syndrome, AMX0114 for Amyotrophic Lateral Sclerosis, and AMX0318 for Post-Bariatric Hypoglycemia and other rare diseases.
33GF Score

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$17.77
Price