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WAVE Life SciencesWVE -0.08%59 Net Debt Paydown Yield % is 0.64% as of Jul. 15, 2026. GuruFocus rates WVE with a GF Score™ of 59/100 and a GF Value™ of $4.36 (Significantly Overvalued). The stock has 2 warning signs investors should review. Among 1,162 Biotechnology companies, WAVE Life Sciences ranks better than 69.71% on this metric.
Net Debt Paydown Yield % is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. It is a measure of a company's willingness and ability to reduce its debt.
As of today, WAVE Life Sciences's Net Debt Paydown Yield % was 0.64%.
WAVE Life Sciences (NAS:WVE) Net Debt Paydown Yield % Explanation
Net Debt Paydown Yield % is the change in average of four quarters of company's total debt over a company's market cap. Assuming the total value of a company remains that same, shareholder value is increased as debt is reduced. In other words, it is a measure of the willingness and ability of a firm's management to pay down debt. Companies that have high debt paydown yields indicate that they are more aggressive with paying down debt.
In the calculation of Net Debt Paydown Yield %, we use the reductions of TTM average total debt one-year-ago and TTM average total debt at present, divided by its Market Cap.
WAVE Life Sciences Net Debt Paydown Yield % Related Terms
WAVE Life Sciences Net Debt Paydown Yield % Historical Data
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The historical data trend for WAVE Life Sciences's Net Debt Paydown Yield % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
WVE vs CGEM, LXRX, XNCR: Net Debt Paydown Yield % Comparison
For the Biotechnology subindustry, WAVE Life Sciences's Net Debt Paydown Yield %, along with its competitors' market caps and Net Debt Paydown Yield % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
WAVE Life Sciences Net Debt Paydown Yield % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, WAVE Life Sciences's Net Debt Paydown Yield % distribution charts can be found below:
* The bar in red indicates where WAVE Life Sciences's Net Debt Paydown Yield % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
* All the data are calculated by TTM values. Note that if a companies is traded in several exchanges, then we calculate the company level data for Net Debt Paydown Yield % using the primary share class stock data. The calculation result in definition page is for demonstration purpose only, and it's showing the share class level data. Therefore, the numbers in the calculation may differ from elsewhere if the stock is not a primary share.
What does a Net Debt Paydown Yield % of 0.64% mean?
WAVE Life Sciences (WVE) has a Net Debt Paydown Yield % of 0.64% as of Jul. 15, 2026. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on WAVE Life Sciences and its competitors. According to the industry distribution chart, WAVE Life Sciences ranks #352 out of 1162 companies in the Biotechnology industry, placing it in the top 30.3%.
Is WAVE Life Sciences' Net Debt Paydown Yield % too high?
WAVE Life Sciences' current Net Debt Paydown Yield % is 0.64%. The Biotechnology industry median Net Debt Paydown Yield % is 0.04. WAVE Life Sciences' value of 0.64% is 1728.6% above this industry median. Based on the distribution chart, WAVE Life Sciences ranks #352 out of 1162 companies in the Biotechnology industry, which is above the industry midpoint. Overall, WAVE Life Sciences has a GF Score™ of 59/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does WAVE Life Sciences' Net Debt Paydown Yield % compare to CGEM and LXRX?
According to the Biotechnology industry distribution chart, WAVE Life Sciences ranks #352 out of 1162 companies for Net Debt Paydown Yield %. This puts WAVE Life Sciences in the upper half of its industry. The industry median Net Debt Paydown Yield % is 0.04. WAVE Life Sciences' value of 0.64% is 1728.6% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Debt Paydown Yield % for a Biotechnology company?
The median Net Debt Paydown Yield % among Biotechnology companies is 0.04, based on 1,162 companies in the industry. Companies in the top quartile (top 25%) have a Net Debt Paydown Yield % significantly above this median, while those in the bottom quartile fall well below. However, Net Debt Paydown Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. WAVE Life Sciences's current Net Debt Paydown Yield % of 0.64% is 1728.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Debt Paydown Yield % mean?
A high Net Debt Paydown Yield % can signal that a stock is expensive relative to its fundamentals. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on WAVE Life Sciences and its competitors. For the Biotechnology industry, the median Net Debt Paydown Yield % is 0.04 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. WAVE Life Sciences's current Net Debt Paydown Yield % is 0.64%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is WAVE Life Sciences stock overvalued right now?
Based on GuruFocus' analysis, WAVE Life Sciences (WVE) is currently considered Significantly Overvalued. The stock's GF Value™ is $4.36, compared to a current price of $6.13 — trading 40.6% above its estimated fair value. The current Net Debt Paydown Yield % is 0.64% and 1728.6% above the Biotechnology industry median of 0.04. WAVE Life Sciences' overall GF Score™ is 59/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Debt Paydown Yield % calculated?
Net Debt Paydown Yield % is calculated from a company's financial statements. For WAVE Life Sciences (WVE), the current Net Debt Paydown Yield % is 0.64% as of Jul. 15, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is WAVE Life Sciences (WVE) Overvalued in 2026?
Based on GuruFocus' analysis, WAVE Life Sciences stock appears to be overvalued.
The current stock price of $6.13 is trading 40.6% above its estimated GF Value™ of $4.36.
GuruFocus considers WAVE Life Sciences to be Significantly Overvalued.
Key valuation signals for WVE:
Net Debt Paydown Yield %: 0.64%
GF Value™: $4.36 vs. price of $6.13 (40.6% above fair value)
Industry Position: 1728.6% above the Biotechnology median (#352 of 1162)
No single metric tells the full story. See the WVE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
WAVE Life Sciences Ltd is a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines also known as oligonucleotides, targeting ribonucleic acid (RNA), to transform human health. RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. Its toolkit of RNA-targeting modalities includes RNA editing, antisense silencing, and RNA interference, providing capabilities for designing and sustainably delivering candidates that optimally address disease biology. Its programs are for rare and prevalent diseases, including alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington's disease.
59GF Score
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