PYXS (Pyxis Oncology) OCF Yield %: -32.72 (As of Aug. 13, 2026)

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PYXS Pyxis Oncology Inc PYXS
27 GF Score
Price $3.23
! 4 Warning Signs
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What is Pyxis Oncology OCF Yield %?

Pyxis Oncology PYXS +1.57% 27 OCF Yield % is -32.72 as of Aug. 13, 2026. GuruFocus rates PYXS with a GF Score™ of 27/100. The stock has 4 warning signs investors should review. Among 1,409 Biotechnology companies, Pyxis Oncology ranks worse than 77.5% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Pyxis Oncology's Trailing 12-Month Cash Flow from Operations is $-66.97 Mil, and Market Cap is $204.64 Mil. Therefore, Pyxis Oncology's OCF Yield % for today is -32.72%.

The historical rank and industry rank for Pyxis Oncology's OCF Yield % or its related term are showing as below:

PYXS' s OCF Yield % Range Over the Past 10 Years
Min: -112.37   Med: -54.96   Max: -19.99
Current: -32.72


During the past 7 years, the highest OCF Yield % of Pyxis Oncology was -19.99%. The lowest was -112.37%. And the median was -54.96%.

PYXS's OCF Yield % is ranked worse than
77.5% of 1409 companies
in the Biotechnology industry
Industry Median: -8.44 vs PYXS: -32.72

Pyxis Oncology's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Pyxis Oncology OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Pyxis Oncology OCF Yield % Related Terms


Pyxis Oncology OCF Yield % Historical Data

* Premium members only.

The historical data trend for Pyxis Oncology's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Pyxis Oncology OCF Yield % Chart

Pyxis Oncology Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial -9.99 -190.70 -87.77 -61.65 -88.08

Pyxis Oncology Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -149.26 -101.22 -38.49 -57.85 -113.37

PYXS vs ORMP, CAMP, ALEC: OCF Yield % Comparison

For the Biotechnology subindustry, Pyxis Oncology's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Pyxis Oncology OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Pyxis Oncology's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Pyxis Oncology's OCF Yield % falls into.


PYXS
27GF Score
Pyxis Oncology Inc PYXS
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Pyxis Oncology OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Pyxis Oncology's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-63.502 / 72.0935
=-88.08%

Pyxis Oncology's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-26 * 4 / 91.73326
=-113.37%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -32.72 mean?
Pyxis Oncology (PYXS) has a OCF Yield % of -32.72 as of Aug. 13, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Pyxis Oncology and its competitors. According to the industry distribution chart, Pyxis Oncology ranks #1092 out of 1409 companies in the Biotechnology industry, placing it in the top 77.5%.
Is Pyxis Oncology's OCF Yield % too high?
Pyxis Oncology's current OCF Yield % is -32.72. Based on the distribution chart, Pyxis Oncology ranks #1092 out of 1409 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Pyxis Oncology has a GF Score™ of 27/100, reflecting its overall financial health beyond just this single metric.
How does Pyxis Oncology's OCF Yield % compare to ORMP and CAMP?
According to the Biotechnology industry distribution chart, Pyxis Oncology ranks #1092 out of 1409 companies for OCF Yield %. This places Pyxis Oncology in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Pyxis Oncology and its competitors. Pyxis Oncology's current OCF Yield % is -32.72. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pyxis Oncology stock overvalued right now?
Pyxis Oncology (PYXS) has a current OCF Yield % of -32.72. The current OCF Yield % is -32.72. Pyxis Oncology's overall GF Score™ is 27/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Pyxis Oncology (PYXS), the current OCF Yield % is -32.72 as of Aug. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Pyxis Oncology Business Description

Address 321 Harrison Avenue, Boston, MA, USA, 02118
Pyxis Oncology Inc is a clinical-stage oncology company focused on developing therapies for patients with solid tumors, with an initial emphasis on head and neck squamous cell carcinoma. Its product candidate, micvotabart pelidotin (MICVO, formerly PYX-201), is an investigational antibody-drug conjugate that targets extradomain-B fibronectin (EDB+FN), a component of the tumor extracellular matrix that is expressed in tumors and minimally present in normal tissues. MICVO consists of a fully human monoclonal antibody linked to a microtubule inhibitor payload, designed to bind within the tumor microenvironment and release its payload to kill cancer cells directly, affect nearby cells through a bystander effect, and induce immunogenic cell death, supporting enhanced anti-tumor activity.
27GF Score

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OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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