PYXS (Pyxis Oncology) Pretax Margin %: % (As of Mar. 2026)

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PYXS Pyxis Oncology Inc PYXS
27 GF Score
Price $3.18
! 4 Warning Signs
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What is Pyxis Oncology Pretax Margin %?

Pyxis Oncology PYXS +13.17% 27 Pretax Margin % is % as of Mar. 2026. GuruFocus rates PYXS with a GF Score™ of 27/100. The stock has 4 warning signs investors should review. Among 945 Biotechnology companies, Pyxis Oncology ranks worse than 72.7% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Pyxis Oncology's Pre-Tax Income for the three months ended in Mar. 2026 was $-23.27 Mil. Pyxis Oncology's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Pyxis Oncology's pretax margin for the quarter that ended in Mar. 2026 was %.

The historical rank and industry rank for Pyxis Oncology's Pretax Margin % or its related term are showing as below:

PYXS' s Pretax Margin % Range Over the Past 10 Years
Min: -579.8   Med: -528.45   Max: -492.35
Current: -579.8


PYXS's Pretax Margin % is ranked worse than
72.7% of 945 companies
in the Biotechnology industry
Industry Median: -85.15 vs PYXS: -579.80

Pyxis Oncology  (NAS:PYXS) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Pyxis Oncology Pretax Margin % Related Terms


Pyxis Oncology Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Pyxis Oncology's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Pyxis Oncology Pretax Margin % Chart

Pyxis Oncology Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial 0.00 0.00 0.00 -492.35 -564.55

Pyxis Oncology Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -640.82 0.00 -154.04 0.00

PYXS vs ORMP, CAMP, ALEC: Pretax Margin % Comparison

For the Biotechnology subindustry, Pyxis Oncology's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Pyxis Oncology Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Pyxis Oncology's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Pyxis Oncology's Pretax Margin % falls into.


PYXS
27GF Score
Pyxis Oncology Inc PYXS
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Pyxis Oncology Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Pyxis Oncology's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-78.235/13.858
=-564.55 %

Pyxis Oncology's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-23.272/0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of % mean?
Pyxis Oncology (PYXS) has a Pretax Margin % of % as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Pyxis Oncology and its competitors. According to the industry distribution chart, Pyxis Oncology ranks #687 out of 945 companies in the Biotechnology industry, placing it in the top 72.7%.
Is Pyxis Oncology's Pretax Margin % too high?
Pyxis Oncology's current Pretax Margin % is %. Based on the distribution chart, Pyxis Oncology ranks #687 out of 945 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Pyxis Oncology has a GF Score™ of 27/100, reflecting its overall financial health beyond just this single metric.
How does Pyxis Oncology's Pretax Margin % compare to ORMP and CAMP?
According to the Biotechnology industry distribution chart, Pyxis Oncology ranks #687 out of 945 companies for Pretax Margin %. This places Pyxis Oncology in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Pyxis Oncology and its competitors. Pyxis Oncology's current Pretax Margin % is %. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pyxis Oncology stock overvalued right now?
Pyxis Oncology (PYXS) has a current Pretax Margin % of %. The current Pretax Margin % is %. Pyxis Oncology's overall GF Score™ is 27/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Pyxis Oncology (PYXS), the current Pretax Margin % is % as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Pyxis Oncology Business Description

Address 321 Harrison Avenue, Boston, MA, USA, 02118
Pyxis Oncology Inc is a clinical-stage oncology company focused on developing therapies for patients with solid tumors, with an initial emphasis on head and neck squamous cell carcinoma. Its product candidate, micvotabart pelidotin (MICVO, formerly PYX-201), is an investigational antibody-drug conjugate that targets extradomain-B fibronectin (EDB+FN), a component of the tumor extracellular matrix that is expressed in tumors and minimally present in normal tissues. MICVO consists of a fully human monoclonal antibody linked to a microtubule inhibitor payload, designed to bind within the tumor microenvironment and release its payload to kill cancer cells directly, affect nearby cells through a bystander effect, and induce immunogenic cell death, supporting enhanced anti-tumor activity.
27GF Score

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Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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