AVAI (Avai Bio) Operating Margin %: 0.00% (As of Dec. 2025)


AVAI Avai Bio Inc AVAI
24 GF Score
Price $0.15
! 3 Warning Signs
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What is Avai Bio Operating Margin %?

Avai Bio AVAI -3.77% 24 Operating Margin % is 0.00% as of Dec. 2025. GuruFocus rates AVAI with a GF Score™ of 24/100. The stock has 3 warning signs investors should review. Among 2,816 Software companies, Avai Bio ranks worse than 35511.33% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Avai Bio's Operating Income for the three months ended in Dec. 2025 was $-0.55 Mil. Avai Bio's Revenue for the three months ended in Dec. 2025 was $0.00 Mil. Therefore, Avai Bio's Operating Margin % for the quarter that ended in Dec. 2025 was 0.00%.

The historical rank and industry rank for Avai Bio's Operating Margin % or its related term are showing as below:


AVAI's Operating Margin % is not ranked *
in the Software industry.
Industry Median: 3.795
* Ranked among companies with meaningful Operating Margin % only.

Avai Bio's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Avai Bio's Operating Income for the three months ended in Dec. 2025 was $-0.55 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was $-1.03 Mil.

Warning Sign:

Avai Bio Inc had lost money in 92% of the time over the past 12quarters.


Avai Bio  (OTCPK:AVAI) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Avai Bio Operating Margin % Related Terms


Avai Bio Operating Margin % Historical Data

* Premium members only.

The historical data trend for Avai Bio's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Avai Bio Operating Margin % Chart

Avai Bio Annual Data
Trend Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25
Operating Margin %
Get a 7-Day Free Trial -24.88 -13.79 -126.45 0.00 0.00

Avai Bio Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

AVAI vs IPM, RCT, LPSN: Operating Margin % Comparison

For the Software - Application subindustry, Avai Bio's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Avai Bio Operating Margin % vs Software Industry

For the Software industry and Technology sector, Avai Bio's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Avai Bio's Operating Margin % falls into.


AVAI
24GF Score
Avai Bio Inc AVAI
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Avai Bio Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Avai Bio's Operating Margin % for the fiscal year that ended in Mar. 2025 is calculated as

Operating Margin %=Operating Income (A: Mar. 2025 ) / Revenue (A: Mar. 2025 )
=-1.142 / 0
= %

Avai Bio's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-0.554 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.00% mean?
Avai Bio (AVAI) has a Operating Margin % of 0.00% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Avai Bio and its competitors. According to the industry distribution chart, Avai Bio ranks #999999 out of 2816 companies in the Software industry.
Is Avai Bio's Operating Margin % too high?
Avai Bio's current Operating Margin % is 0.00%. Based on the distribution chart, Avai Bio ranks #999999 out of 2816 companies in the Software industry, which is in the bottom quartile relative to peers. Overall, Avai Bio has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does Avai Bio's Operating Margin % compare to IPM and RCT?
According to the Software industry distribution chart, Avai Bio ranks #999999 out of 2816 companies for Operating Margin %. This places Avai Bio in the lower half of its industry. The industry median Operating Margin % is 3.80. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Software company?
The median Operating Margin % among Software companies is 3.80, based on 2,816 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Avai Bio and its competitors. For the Software industry, the median Operating Margin % is 3.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Avai Bio's current Operating Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avai Bio stock overvalued right now?
Avai Bio (AVAI) has a current Operating Margin % of 0.00%. The current Operating Margin % is 0.00%. Avai Bio's overall GF Score™ is 24/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Avai Bio (AVAI), the current Operating Margin % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Avai Bio Business Description

Address 5348 Vegas Drive, Las Vegas, NV, USA, 89108
Avai Bio Inc is a biotechnology company focused on identifying genetically modified cell lines, and through joint venture and licensing agreements, developing cell-based therapies. The company has two development programs in its cellular therapies pipeline, a diabetes development program to advance a treatment for type 1 and type 2 insulin-dependent diabetes, and an ?-Klotho protein development program to advance therapies for age-related diseases and anti-aging treatments.
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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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