Adagene (FRA:978) Owner Earnings per Share (TTM): -0.33 (As of Dec. 2025)

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FRA:978 Adagene Inc FRA:978
42 GF Score
Price €3.08
GF Value €12.88
! 3 Warning Signs
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What is Adagene Owner Earnings per Share (TTM)?

Adagene FRA:978 -0.65% 42 Owner Earnings per Share (TTM) is -0.33 as of Dec. 2025. GuruFocus rates FRA:978 with a GF Score™ of 42/100 and a GF Value™ of €12.88. The stock has 3 warning signs investors should review. Among 207 Biotechnology companies, Adagene ranks worse than 483091.3% on this metric.

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

Adagene's Owner Earnings per Share (TTM) ended in Dec. 2025 was €-0.33. It's Price-to-Owner-Earnings ratio for today is 0.


The historical rank and industry rank for Adagene's Owner Earnings per Share (TTM) or its related term are showing as below:



FRA:978's Price-to-Owner-Earnings is not ranked *
in the Biotechnology industry.
Industry Median: 25.64
* Ranked among companies with meaningful Price-to-Owner-Earnings only.

Adagene's Earnings per Share (Diluted) for the six months ended in Jun. 2026 was €-0.25. Its Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was €-0.33. It's PE Ratio (TTM) ratio for today is At Loss.

Adagene's EPS without NRI for the six months ended in Jun. 2026 was €-0.23. Its EPS without NRI for the trailing twelve months (TTM) ended in Jun. 2026 was €-0.31. It's PE Ratio without NRI ratio for today is At Loss.


Be Aware

Assumption: Companies usually do not report maintenance capital expenditures and growth capital expenditures separately. Here we use estimated numbers and average them over 5 years. The method to estimate maintenance capital expenditures can be found in above part 4.

Note: GuruFocus' Change In Working Capital is provided by Morningstar. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And it includes non-current parts of assets and liabilities.


Adagene Owner Earnings per Share (TTM) Related Terms


Adagene Owner Earnings per Share (TTM) Historical Data

* Premium members only.

The historical data trend for Adagene's Owner Earnings per Share (TTM) can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Adagene Owner Earnings per Share (TTM) Chart

Adagene Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Owner Earnings per Share (TTM)
Get a 7-Day Free Trial 0.00 -1.08 -0.62 -0.71 -0.30

Adagene Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25 Jun26
Owner Earnings per Share (TTM) Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -0.71 0.00 -0.30 0.00

FRA:978 vs SLNCF, NBP, NAUT: Owner Earnings per Share (TTM) Comparison

For the Biotechnology subindustry, Adagene's Price-to-Owner-Earnings, along with its competitors' market caps and Price-to-Owner-Earnings data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Adagene Price-to-Owner-Earnings vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Adagene's Price-to-Owner-Earnings distribution charts can be found below:

* The bar in red indicates where Adagene's Price-to-Owner-Earnings falls into.


FRA:978
42GF Score
Adagene Inc FRA:978
Owner Earnings per Share (TTM) is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Adagene Owner Earnings per Share (TTM) Calculation

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume. (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

To make it simple, then you will have:

Owner Earnings per Share (TTM) = (Net Income + Depreciation, Depletion and Amortization + Change In Deferred Tax - 5Y Average of Maintenance Capital Expenditure + Change In Working Capital) / Shares Outstanding (Diluted Average)

Adagene's Owner Earnings per Share (TTM) Calculation:

Last Year Average of Last 5 Years
Net Income -15.04
Depreciation, Depletion and Amortization 0.50
Change In Deferred Tax 0.00
5Y Average of Maintenance Capital Expenditure 0.60
Change In Working Capital -0.66
Shares Outstanding (Diluted Average) 47.21

1. Start with "Net Income" from income statement. Adagene's Net Income for the trailing twelve months (TTM) ended in Dec. 2025 was €-15.04 Mil.

2. "Depreciation, Depletion and Amortization" is from cashflow statement. Adagene's Depreciation, Depletion and Amortization for the trailing twelve months (TTM) ended in Dec. 2025 was €0.50 Mil. This needs to be added back because company does not actually need to pay cash for it. It is a non-cash item.

3. Other non-cash charges usually include "Stock Based Compensation" and "Change In Deferred Tax":
However, to be conservative, GuruFocus will not add Stock Based Compensation back to net income. Adagene's Change In Deferred Tax for the trailing twelve months (TTM) ended in Dec. 2025 was €0.00 Mil.

4. Average maintenance capital expenditure over a business/industry cycle: 5-Year Average Maintenance Capital Expenditure = €0.60 Mil

It is usually best to take a long-term average of maintenance capital expenditure. Ideally this would be as long as 10 years and include at least one economic downturn. However, since many companies do not have as long as 10-year history, here GuruFocus uses the latest 5 years data to do the calculation. To smooth out unusual years but reflect recent developments, we take an average of the 5 year maintenance capital expenditure.

The following shows how to get maintenance capital expenditure.

First, calculate the revenue change regarding to the previous year. If the revenue decreased from the previous year, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
Second, if the revenue increased from the previous year, then calculate the percentage of Net PPE as of corresponding Revenue.
Growth Capital Expenditure = Percentage of Property, Plant and Equipment as of corresponding Revenue * Revenue Increase
Third, calculate Capital Expenditure (positive) - Growth Capital Expenditure.
If [Capital Expenditure (positive) - Growth Capital Expenditure] was negative, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
If [Capital Expenditure (positive) - Growth Capital Expenditure] was positive, then the Maintenance Capital Expenditure = Capital Expenditure (positive) - Growth Capital Expenditure.
Fourth, get the average of the 5 years maintenance capital expenditure.

Adagene's 5-Year Average Maintenance Capital Expenditure = €0.60 Mil

5. "Change In Working Capital" is from cashflow statement. Adagene's Change In Working Capital for the trailing twelve months (TTM) ended in Dec. 2025 was €-0.66 Mil.
Note: GuruFocus' Change in Working Capital is provided by Morningstar. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And sometimes it includes non-current parts of assets and liabilities.

6. Adagene's Shares Outstanding (Diluted Average) for the months ended in Dec. 2025 was 47.205 Mil.

Adagene's Onwer Earnings Per Share for Dec. 2025 is calculated as:

Owner Earnings per Share (TTM)
=( Net Income+Depreciation, Depletion and Amortization+Change In Deferred Tax
=( -15.038 +0.504+0
-5Y Avg of Maintenance CAPEX+Change In Working Capital )/Shares Outstanding (Diluted Average)
-0.6+-0.662)/47.205
=-0.33

Price-to-Owner-Earnings=Current Price/Owner Earnings per Share (TTM)
=3.08/-0.33
=0

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Owner Earnings per Share (TTM) of -0.33 mean?
Adagene (FRA:978) has a Owner Earnings per Share (TTM) of -0.33 as of Dec. 2025. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Adagene. According to the industry distribution chart, Adagene ranks #999999 out of 207 companies in the Biotechnology industry.
Is Adagene's Owner Earnings per Share (TTM) too high?
Adagene's current Owner Earnings per Share (TTM) is -0.33. Based on the distribution chart, Adagene ranks #999999 out of 207 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Adagene has a GF Score™ of 42/100, reflecting its overall financial health beyond just this single metric.
How does Adagene's Owner Earnings per Share (TTM) compare to SLNCF and NBP?
According to the Biotechnology industry distribution chart, Adagene ranks #999999 out of 207 companies for Owner Earnings per Share (TTM). This places Adagene in the lower half of its industry. The industry median Owner Earnings per Share (TTM) is 25.64. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Owner Earnings per Share (TTM) for a Biotechnology company?
The median Owner Earnings per Share (TTM) among Biotechnology companies is 25.64, based on 207 companies in the industry. Companies in the top quartile (top 25%) have a Owner Earnings per Share (TTM) significantly above this median, while those in the bottom quartile fall well below. However, Owner Earnings per Share (TTM) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Owner Earnings per Share (TTM) mean?
A high Owner Earnings per Share (TTM) can signal that a stock is expensive relative to its fundamentals. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Adagene. For the Biotechnology industry, the median Owner Earnings per Share (TTM) is 25.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Adagene's current Owner Earnings per Share (TTM) is -0.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Adagene stock overvalued right now?
Adagene (FRA:978) has a current Owner Earnings per Share (TTM) of -0.33. The stock's GF Value™ is €12.88, compared to a current price of €3.08 — trading 76.1% below its estimated fair value. The current Owner Earnings per Share (TTM) is -0.33. Adagene's overall GF Score™ is 42/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Owner Earnings per Share (TTM) calculated?
Owner Earnings per Share (TTM) is calculated from a company's financial statements. For Adagene (FRA:978), the current Owner Earnings per Share (TTM) is -0.33 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Adagene (FRA:978) Overvalued in 2026?

Based on GuruFocus' analysis, Adagene stock appears to be undervalued. The current stock price of €3.08 is trading 76.1% below its estimated GF Value™ of €12.88.

Key valuation signals for FRA:978:

  • Owner Earnings per Share (TTM): -0.33
  • GF Value™: €12.88 vs. price of €3.08 (76.1% below fair value)
  • GF Score™: 42/100 with 3 warning signs

No single metric tells the full story. See the FRA:978 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Adagene Business Description

Other Exchanges ADAG:USA
Address Xinghu Street, Suzhou Industrial Park, 4th Floor, Building C14, No. 218, Jiangsu Province, Suzhou, CHN, 215123
Adagene Inc is a platform-driven, clinical-stage biotechnology company focused on the discovery and development of novel antibody-based cancer immunotherapies. The Company leverages computational biology to design and develop novel antibodies. Powered by its Dynamic Precision Library (DPL) platform, which fuels its NEObody, SAFEbody, and POWERbody technologies, it is developing a pipeline of immunotherapies. Its candidate, ADG126 (muzastotug), an anti-CTLA-4 SAFEbody, is in phase 1b/2 and phase 2 clinical development for metastatic microsatellite-stable colorectal cancer. Its clinical-stage products include ADG126 and ADG116, investigational fully human anti-CTLA-4 mAbs generated through SAFEbody and NEObody technologies.
42GF Score

Get the complete analysis for FRA:978

Owner Earnings per Share (TTM) is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.08
Price
€12.88
GF Value