AdageneFRA:978 -0.61%42 PB Ratio is 5.12 as of Jul. 11, 2026, which is 241% above its 10-year median of 1.50. GuruFocus rates FRA:978 with a GF Score™ of 42/100 and a GF Value™ of €11.95. The stock has 3 warning signs investors should review. Among 1,227 Biotechnology companies, Adagene ranks worse than 69.52% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-07-11), Adagene's share price is €3.26. Adagene's Book Value per Share for the quarter that ended in Dec. 2025 was €0.64. Hence, Adagene's PB Ratio of today is 5.12.
The historical rank and industry rank for Adagene's PB Ratio or its related term are showing as below:
FRA:978'
s PB Ratio Range Over the Past 10 Years
Min: 0.27 Med: 1.5 Max: 5.99
Current: 5.15
During the past 8 years, Adagene's highest PB Ratio was 5.99. The lowest was 0.27. And the median was 1.50.
FRA:978's PB Ratio is ranked worse than 69.52% of 1227
companies
in the Biotechnology industry
Industry Median: 2.95
vs FRA:978: 5.15
During the past 12 months, Adagene's average Book Value Per Share Growth Rate was -30.40% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -27.00% per year.
During the past 8 years, the highest 3-Year average Book Value Per Share Growth Rate of Adagene was -27.00% per year. The lowest was -33.10% per year. And the median was -30.05% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Adagene PB Ratio Related Terms
Adagene PB Ratio Historical Data
* Premium members only.
The historical data trend for Adagene's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Adagene's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Adagene PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Adagene's PB Ratio distribution charts can be found below:
* The bar in red indicates where Adagene's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
Adagene's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Adagene (FRA:978) has a PB Ratio of 5.12 as of Jul. 11, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Adagene and its competitors. This is 241% above median its historical median of 1.50. Over the past decade, Adagene's PB Ratio has ranged from 0.27 to 5.99. According to the industry distribution chart, Adagene ranks #853 out of 1227 companies in the Biotechnology industry, placing it in the top 69.5%.
Is Adagene's PB Ratio too high?
Adagene's current PB Ratio of 5.12 is 241% above median its 10-year median of 1.50. Over the past 10 years, this metric has ranged from a low of 0.27 to a high of 5.99. The Biotechnology industry median PB Ratio is 2.95. Adagene's value of 5.12 is 73.6% above this industry median. Based on the distribution chart, Adagene ranks #853 out of 1227 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Adagene has a GF Score™ of 42/100, reflecting its overall financial health beyond just this single metric.
How does Adagene's PB Ratio compare to RNAC and LYEL?
According to the Biotechnology industry distribution chart, Adagene ranks #853 out of 1227 companies for PB Ratio. This places Adagene in the lower half of its industry. The industry median PB Ratio is 2.95. Adagene's value of 5.12 is 73.6% above this benchmark. Historically, Adagene's own PB Ratio has ranged from 0.27 to 5.99 over the past decade. While the company's 10-year median is 1.50 vs. the industry median of 2.95, Adagene has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.95, based on 1,227 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Adagene's current PB Ratio of 5.12 is 73.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Adagene and its competitors. For the Biotechnology industry, the median PB Ratio is 2.95 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Adagene's current PB Ratio is 5.12, which is 241% above median its own 10-year median of 1.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Adagene stock overvalued right now?
Adagene (FRA:978) has a current PB Ratio of 5.12. The stock's GF Value™ is €11.95, compared to a current price of €3.26 — trading 72.7% below its estimated fair value. The current PB Ratio is 5.12, which is 241% above median its 10-year median of 1.50 and 73.6% above the Biotechnology industry median of 2.95. Adagene's overall GF Score™ is 42/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Adagene (FRA:978), the current PB Ratio is 5.12 as of Jul. 11, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Adagene (FRA:978) Overvalued in 2026?
Based on GuruFocus' analysis, Adagene stock appears to be undervalued.
The current stock price of €3.26 is trading 72.7% below its estimated GF Value™ of €11.95.
Key valuation signals for FRA:978:
PB Ratio: 5.12 (241% above median its 10-year median of 1.50)
GF Value™: €11.95 vs. price of €3.26 (72.7% below fair value)
Industry Position: 73.6% above the Biotechnology median (#853 of 1227)
No single metric tells the full story. See the FRA:978 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Adagene Inc is a platform-driven, clinical-stage biotechnology company focused on the discovery and development of novel antibody-based cancer immunotherapies. The Company leverages computational biology to design and develop novel antibodies. Powered by its Dynamic Precision Library (DPL) platform, which fuels its NEObody, SAFEbody, and POWERbody technologies, it is developing a pipeline of immunotherapies. Its candidate, ADG126 (muzastotug), an anti-CTLA-4 SAFEbody, is in phase 1b/2 and phase 2 clinical development for metastatic microsatellite-stable colorectal cancer. Its clinical-stage products include ADG126 and ADG116, investigational fully human anti-CTLA-4 mAbs generated through SAFEbody and NEObody technologies.
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