Adagene (FRA:978) 3-Year RORE % : -5.43% (As of Dec. 2025)


FRA:978 Adagene Inc FRA:978
42 GF Score
Price €3.26
GF Value €11.64
! 3 Warning Signs
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What is Adagene 3-Year RORE %?

Adagene FRA:978 -0.61% 42 3-Year RORE % is -5.43 as of Dec. 2025. GuruFocus rates FRA:978 with a GF Score™ of 42/100 and a GF Value™ of €11.64. The stock has 3 warning signs investors should review. Among 1,291 Biotechnology companies, Adagene ranks better than 58.79% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. Adagene's 3-Year RORE % for the quarter that ended in Dec. 2025 was -5.43%.

The industry rank for Adagene's 3-Year RORE % or its related term are showing as below:

FRA:978's 3-Year RORE % is ranked better than
58.79% of 1291 companies
in the Biotechnology industry
Industry Median: -11.44 vs FRA:978: -5.43

Adagene  (FRA:978) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


Adagene 3-Year RORE % Related Terms


Adagene 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for Adagene's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Adagene 3-Year RORE % Chart

Adagene Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year RORE %
Get a 7-Day Free Trial 0.00 21.13 -31.22 -37.10 -5.43

Adagene Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -31.22 -33.19 -37.10 -11.09 -5.43

FRA:978 vs RNAC, LYEL, ALXO: 3-Year RORE % Comparison

For the Biotechnology subindustry, Adagene's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Adagene 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Adagene's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where Adagene's 3-Year RORE % falls into.


FRA:978
42GF Score
Adagene Inc FRA:978
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Adagene 3-Year RORE % Calculation

Adagene's 3-Year RORE % for the quarter that ended in Dec. 2025 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( -0.324--0.401 )/( -1.419-0 )
=0.077/-1.419
=-5.43 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Dec. 2025 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of -5.43 mean?
Adagene (FRA:978) has a 3-Year RORE % of -5.43 as of Dec. 2025. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Adagene and its competitors. According to the industry distribution chart, Adagene ranks #532 out of 1291 companies in the Biotechnology industry, placing it in the top 41.2%.
Is Adagene's 3-Year RORE % too high?
Adagene's current 3-Year RORE % is -5.43. Based on the distribution chart, Adagene ranks #532 out of 1291 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Adagene has a GF Score™ of 42/100, reflecting its overall financial health beyond just this single metric.
How does Adagene's 3-Year RORE % compare to RNAC and LYEL?
According to the Biotechnology industry distribution chart, Adagene ranks #532 out of 1291 companies for 3-Year RORE %. This puts Adagene in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on Adagene and its competitors. Adagene's current 3-Year RORE % is -5.43. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Adagene stock overvalued right now?
Adagene (FRA:978) has a current 3-Year RORE % of -5.43. The stock's GF Value™ is €11.64, compared to a current price of €3.26 — trading 72% below its estimated fair value. The current 3-Year RORE % is -5.43. Adagene's overall GF Score™ is 42/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For Adagene (FRA:978), the current 3-Year RORE % is -5.43 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Adagene (FRA:978) Overvalued in 2026?

Based on GuruFocus' analysis, Adagene stock appears to be undervalued. The current stock price of €3.26 is trading 72% below its estimated GF Value™ of €11.64.

Key valuation signals for FRA:978:

  • 3-Year RORE %: -5.43
  • GF Value™: €11.64 vs. price of €3.26 (72% below fair value)
  • GF Score™: 42/100 with 3 warning signs

No single metric tells the full story. See the FRA:978 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Adagene Business Description

Other Exchanges ADAG:USA
Address Xinghu Street, Suzhou Industrial Park, 4th Floor, Building C14, No. 218, Jiangsu Province, Suzhou, CHN, 215123
Adagene Inc is a platform-driven, clinical-stage biotechnology company focused on the discovery and development of novel antibody-based cancer immunotherapies. The Company leverages computational biology to design and develop novel antibodies. Powered by its Dynamic Precision Library (DPL) platform, which fuels its NEObody, SAFEbody, and POWERbody technologies, it is developing a pipeline of immunotherapies. Its candidate, ADG126 (muzastotug), an anti-CTLA-4 SAFEbody, is in phase 1b/2 and phase 2 clinical development for metastatic microsatellite-stable colorectal cancer. Its clinical-stage products include ADG126 and ADG116, investigational fully human anti-CTLA-4 mAbs generated through SAFEbody and NEObody technologies.
42GF Score

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3-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.26
Price
€11.64
GF Value