4SC AGFRA:VSC PB Ratio is 5.56 as of Jun. 25, 2026, which is 92% above its 10-year median of 2.89. The stock has 7 warning signs investors should review.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-06-25), 4SC AG's share price is €0.10. 4SC AG's Book Value per Share for the quarter that ended in Dec. 2025 was €0.02. Hence, 4SC AG's PB Ratio of today is 5.56.
The historical rank and industry rank for 4SC AG's PB Ratio or its related term are showing as below:
FRA:VSC'
s PB Ratio Range Over the Past 10 Years
Min: 0.44 Med: 2.89 Max: 80.28
Current: 5.56
During the past 13 years, 4SC AG's highest PB Ratio was 80.28. The lowest was 0.44. And the median was 2.89.
FRA:VSC's PB Ratio is not ranked
in the Biotechnology industry.
Industry Median: 2.8
vs FRA:VSC: 5.56
During the past 12 months, 4SC AG's average Book Value Per Share Growth Rate was -74.60% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -76.10% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -66.80% per year.
During the past 10 years, the average Book Value Per Share Growth Rate was -40.20% per year.
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of 4SC AG was 96.30% per year. The lowest was -76.10% per year. And the median was -19.10% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
4SC AG PB Ratio Related Terms
4SC AG PB Ratio Historical Data
* Premium members only.
The historical data trend for 4SC AG's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, 4SC AG's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
4SC AG PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, 4SC AG's PB Ratio distribution charts can be found below:
* The bar in red indicates where 4SC AG's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
4SC AG's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
4SC AG (FRA:VSC) has a PB Ratio of 5.56 as of Jun. 25, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on 4SC AG and its competitors. This is 92% above median its historical median of 2.89. Over the past decade, 4SC AG's PB Ratio has ranged from 0.44 to 80.28.
Is 4SC AG's PB Ratio too high?
4SC AG's current PB Ratio of 5.56 is 92% above median its 10-year median of 2.89. Over the past 10 years, this metric has ranged from a low of 0.44 to a high of 80.28. The Biotechnology industry median PB Ratio is 2.80. 4SC AG's value of 5.56 is 98.6% above this industry median.
How does 4SC AG's PB Ratio compare to VRTX and REGN?
4SC AG's PB Ratio of 5.56 can be compared against companies in the Biotechnology industry. The industry median PB Ratio is 2.80. 4SC AG's value of 5.56 is 98.6% above this benchmark. Historically, 4SC AG's own PB Ratio has ranged from 0.44 to 80.28 over the past decade. While the company's 10-year median is 2.89 vs. the industry median of 2.80, 4SC AG has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.80, based on 1,233 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. 4SC AG's current PB Ratio of 5.56 is 98.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on 4SC AG and its competitors. For the Biotechnology industry, the median PB Ratio is 2.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. 4SC AG's current PB Ratio is 5.56, which is 92% above median its own 10-year median of 2.89. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 4SC AG stock overvalued right now?
4SC AG (FRA:VSC) has a current PB Ratio of 5.56. The stock's GF Value™ is €3.51, compared to a current price of €0.10 — trading 97.2% below its estimated fair value. The current PB Ratio is 5.56, which is 92% above median its 10-year median of 2.89 and 98.6% above the Biotechnology industry median of 2.80. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For 4SC AG (FRA:VSC), the current PB Ratio is 5.56 as of Jun. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
4SC AG is a clinical-stage biopharmaceutical company developing small-molecule drugs that can target key indications in cancer with high unmet medical needs. Its pipeline is protected by a comprehensive portfolio of patents and currently comprises two drug candidates in clinical development resminostat and Domatinostat. The geographic area of the company is Germany, the EU, and Other countries, and the majority of the revenue comes from Other Countries.
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