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Shattuck LabsSTTK +4.80%42 PB Ratio is 5.85 as of Jul. 26, 2026, which is 442% above its 10-year median of 1.08. GuruFocus rates STTK with a GF Score™ of 42/100 and a GF Value™ of $1.05 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 1,231 Biotechnology companies, Shattuck Labs ranks worse than 74.9% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-07-26), Shattuck Labs's share price is $7.42. Shattuck Labs's Book Value per Share for the quarter that ended in Mar. 2026 was $1.27. Hence, Shattuck Labs's PB Ratio of today is 5.85.
Warning Sign:
Shattuck Labs Inc stock PB Ratio (=5.85) is close to 5-year high of 6.1.
The historical rank and industry rank for Shattuck Labs's PB Ratio or its related term are showing as below:
STTK'
s PB Ratio Range Over the Past 10 Years
Min: 0.43 Med: 1.08 Max: 7.06
Current: 5.85
During the past 8 years, Shattuck Labs's highest PB Ratio was 7.06. The lowest was 0.43. And the median was 1.08.
STTK's PB Ratio is ranked worse than 74.9% of 1231
companies
in the Biotechnology industry
Industry Median: 2.77
vs STTK: 5.85
During the past 12 months, Shattuck Labs's average Book Value Per Share Growth Rate was -10.10% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -32.10% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -31.10% per year.
During the past 8 years, the highest 3-Year average Book Value Per Share Growth Rate of Shattuck Labs was -25.50% per year. The lowest was -36.20% per year. And the median was -32.10% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Shattuck Labs PB Ratio Related Terms
Shattuck Labs PB Ratio Historical Data
* Premium members only.
The historical data trend for Shattuck Labs's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Shattuck Labs's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Shattuck Labs PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Shattuck Labs's PB Ratio distribution charts can be found below:
* The bar in red indicates where Shattuck Labs's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
Shattuck Labs's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Shattuck Labs (STTK) has a PB Ratio of 5.85 as of Jul. 26, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Shattuck Labs and its competitors. This is 442% above median its historical median of 1.08. Over the past decade, Shattuck Labs' PB Ratio has ranged from 0.43 to 7.06. According to the industry distribution chart, Shattuck Labs ranks #922 out of 1231 companies in the Biotechnology industry, placing it in the top 74.9%.
Is Shattuck Labs' PB Ratio too high?
Shattuck Labs' current PB Ratio of 5.85 is 442% above median its 10-year median of 1.08. Over the past 10 years, this metric has ranged from a low of 0.43 to a high of 7.06. The Biotechnology industry median PB Ratio is 2.77. Shattuck Labs' value of 5.85 is 111.2% above this industry median. Based on the distribution chart, Shattuck Labs ranks #922 out of 1231 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Shattuck Labs has a GF Score™ of 42/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shattuck Labs' PB Ratio compare to ACHV and CRMD?
According to the Biotechnology industry distribution chart, Shattuck Labs ranks #922 out of 1231 companies for PB Ratio. This places Shattuck Labs in the lower half of its industry. The industry median PB Ratio is 2.77. Shattuck Labs' value of 5.85 is 111.2% above this benchmark. Historically, Shattuck Labs' own PB Ratio has ranged from 0.43 to 7.06 over the past decade. While the company's 10-year median is 1.08 vs. the industry median of 2.77, Shattuck Labs has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.77, based on 1,231 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Shattuck Labs's current PB Ratio of 5.85 is 111.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Shattuck Labs and its competitors. For the Biotechnology industry, the median PB Ratio is 2.77 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Shattuck Labs's current PB Ratio is 5.85, which is 442% above median its own 10-year median of 1.08. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shattuck Labs stock overvalued right now?
Based on GuruFocus' analysis, Shattuck Labs (STTK) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.05, compared to a current price of $7.42 — trading 606.7% above its estimated fair value. The current PB Ratio is 5.85, which is 442% above median its 10-year median of 1.08 and 111.2% above the Biotechnology industry median of 2.77. Shattuck Labs' overall GF Score™ is 42/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Shattuck Labs (STTK), the current PB Ratio is 5.85 as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Shattuck Labs (STTK) Overvalued in 2026?
Based on GuruFocus' analysis, Shattuck Labs stock appears to be overvalued.
The current stock price of $7.42 is trading 606.7% above its estimated GF Value™ of $1.05.
GuruFocus considers Shattuck Labs to be Significantly Overvalued.
Key valuation signals for STTK:
PB Ratio: 5.85 (442% above median its 10-year median of 1.08)
GF Value™: $1.05 vs. price of $7.42 (606.7% above fair value)
Industry Position: 111.2% above the Biotechnology median (#922 of 1231)
No single metric tells the full story. See the STTK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Shattuck Labs Inc is a biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. It is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. The company's expertise in protein engineering and the development of novel tumor necrosis factor (TNF) receptor therapeutics comes together in its main program, SL-325, which has the potential to be a first-in-class death receptor 3 (DR3) antagonist antibody. In addition, the company is developing SL-425, a half-life extended version of SL-325, and multiple other preclinical DR3-based bispecific antibodies, for the treatment of patients with IBD.
42GF Score
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