CRBU (Caribou Biosciences) Pretax Margin %: -1,046.52% (As of Mar. 2026)


CRBU Caribou Biosciences Inc CRBU
65 GF Score
Price $1.81
GF Value $1.69
Valuation Fairly Valued
! 5 Warning Signs
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What is Caribou Biosciences Pretax Margin %?

Caribou Biosciences CRBU +2.56% 65 Pretax Margin % is -1,046.52% as of Mar. 2026. GuruFocus rates CRBU with a GF Score™ of 65/100 and a GF Value™ of $1.69 (Fairly Valued). The stock has 5 warning signs investors should review. Among 942 Biotechnology companies, Caribou Biosciences ranks worse than 80.15% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Caribou Biosciences's Pre-Tax Income for the three months ended in Mar. 2026 was $-25.09 Mil. Caribou Biosciences's Revenue for the three months ended in Mar. 2026 was $2.40 Mil. Therefore, Caribou Biosciences's pretax margin for the quarter that ended in Mar. 2026 was -1,046.52%.

The historical rank and industry rank for Caribou Biosciences's Pretax Margin % or its related term are showing as below:

CRBU' s Pretax Margin % Range Over the Past 10 Years
Min: -1492.04   Med: -693.92   Max: -292.27
Current: -1194.05


CRBU's Pretax Margin % is ranked worse than
80.15% of 942 companies
in the Biotechnology industry
Industry Median: -90.5 vs CRBU: -1194.05

Caribou Biosciences  (NAS:CRBU) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Caribou Biosciences Pretax Margin % Related Terms


Caribou Biosciences Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Caribou Biosciences's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Caribou Biosciences Pretax Margin % Chart

Caribou Biosciences Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial -693.92 -717.28 -295.49 -1,492.04 -1,332.33

Caribou Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,699.58 -2,028.42 -1,253.32 -686.07 -1,046.52

CRBU vs YDES, PRQR, CRBP: Pretax Margin % Comparison

For the Biotechnology subindustry, Caribou Biosciences's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Caribou Biosciences Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Caribou Biosciences's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Caribou Biosciences's Pretax Margin % falls into.


CRBU
65GF Score
Caribou Biosciences Inc CRBU
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Caribou Biosciences Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Caribou Biosciences's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-148.675/11.159
=-1,332.33 %

Caribou Biosciences's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-25.085/2.397
=-1,046.52 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -1,046.52% mean?
Caribou Biosciences (CRBU) has a Pretax Margin % of -1,046.52% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Caribou Biosciences and its competitors. According to the industry distribution chart, Caribou Biosciences ranks #755 out of 942 companies in the Biotechnology industry, placing it in the top 80.1%.
Is Caribou Biosciences' Pretax Margin % too high?
Caribou Biosciences' current Pretax Margin % is -1,046.52%. Based on the distribution chart, Caribou Biosciences ranks #755 out of 942 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Caribou Biosciences has a GF Score™ of 65/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Caribou Biosciences' Pretax Margin % compare to YDES and PRQR?
According to the Biotechnology industry distribution chart, Caribou Biosciences ranks #755 out of 942 companies for Pretax Margin %. This places Caribou Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Caribou Biosciences and its competitors. Caribou Biosciences's current Pretax Margin % is -1,046.52%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Caribou Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Caribou Biosciences (CRBU) is currently considered Fairly Valued. The stock's GF Value™ is $1.69, compared to a current price of $1.81 — trading 6.8% above its estimated fair value. The current Pretax Margin % is -1,046.52%. Caribou Biosciences' overall GF Score™ is 65/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Caribou Biosciences (CRBU), the current Pretax Margin % is -1,046.52% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Caribou Biosciences (CRBU) Overvalued in 2026?

Based on GuruFocus' analysis, Caribou Biosciences stock appears to be overvalued. The current stock price of $1.81 is trading 6.8% above its estimated GF Value™ of $1.69. GuruFocus considers Caribou Biosciences to be Fairly Valued.

Key valuation signals for CRBU:

  • Pretax Margin %: -1,046.52%
  • GF Value™: $1.69 vs. price of $1.81 (6.8% above fair value)
  • GF Score™: 65/100 with 5 warning signs

No single metric tells the full story. See the CRBU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Caribou Biosciences Business Description

Address 2929 7th Street, Suite 105, Berkeley, CA, USA, 94710
Caribou Biosciences Inc is a clinical-stage Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company is focused on advancing two clinical-stage allogeneic CAR-T cell therapy product candidates for the treatment of patients with hematologic malignancies: Vispacabtagene regedleucel and CB-011. It operates in one reportable segment, which is the business of developing allogeneic CAR-T cell therapies. Geographically, it operates in the United States and the rest of the World, of which the United States derives the maximum revenue.
65GF Score

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Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.81
Price
$1.69
GF Value