CRBU (Caribou Biosciences) ROA %: -61.87% (As of Mar. 2026)


CRBU Caribou Biosciences Inc CRBU
66 GF Score
Price $1.67
GF Value $1.70
Valuation Fairly Valued
! 5 Warning Signs
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What is Caribou Biosciences ROA %?

Caribou Biosciences CRBU +7.01% 66 ROA % is -61.87% as of Mar. 2026. GuruFocus rates CRBU with a GF Score™ of 66/100 and a GF Value™ of $1.70 (Fairly Valued). The stock has 5 warning signs investors should review. Among 1,419 Biotechnology companies, Caribou Biosciences ranks worse than 72.23% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Caribou Biosciences's annualized Net Income for the quarter that ended in Mar. 2026 was $-100.34 Mil. Caribou Biosciences's average Total Assets over the quarter that ended in Mar. 2026 was $162.18 Mil. Therefore, Caribou Biosciences's annualized ROA % for the quarter that ended in Mar. 2026 was -61.87%.

The historical rank and industry rank for Caribou Biosciences's ROA % or its related term are showing as below:

CRBU' s ROA % Range Over the Past 10 Years
Min: -70.03   Med: -37.83   Max: -24.36
Current: -65.7

During the past 7 years, Caribou Biosciences's highest ROA % was -24.36%. The lowest was -70.03%. And the median was -37.83%.

CRBU's ROA % is ranked worse than
72.23% of 1419 companies
in the Biotechnology industry
Industry Median: -32.84 vs CRBU: -65.70

Caribou Biosciences  (NAS:CRBU) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-100.34/162.1825
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-100.34 / 9.588)*(9.588 / 162.1825)
=Net Margin %*Asset Turnover
=-1046.52 %*0.0591
=-61.87 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Caribou Biosciences ROA % Related Terms


Caribou Biosciences ROA % Historical Data

* Premium members only.

The historical data trend for Caribou Biosciences's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Caribou Biosciences ROA % Chart

Caribou Biosciences Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial -27.98 -24.36 -25.33 -40.00 -60.62

Caribou Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -54.51 -87.51 -52.99 -57.22 -61.87

CRBU vs YDES, PRQR, CRBP: ROA % Comparison

For the Biotechnology subindustry, Caribou Biosciences's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Caribou Biosciences ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Caribou Biosciences's ROA % distribution charts can be found below:

* The bar in red indicates where Caribou Biosciences's ROA % falls into.


CRBU
66GF Score
Caribou Biosciences Inc CRBU
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Caribou Biosciences ROA % Calculation

Caribou Biosciences's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-148.125/( (313.313+175.367)/ 2 )
=-148.125/244.34
=-60.62 %

Caribou Biosciences's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-100.34/( (175.367+148.998)/ 2 )
=-100.34/162.1825
=-61.87 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -61.87% mean?
Caribou Biosciences (CRBU) has a ROA % of -61.87% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Caribou Biosciences and its competitors. According to the industry distribution chart, Caribou Biosciences ranks #1025 out of 1419 companies in the Biotechnology industry, placing it in the top 72.2%.
Is Caribou Biosciences' ROA % too high?
Caribou Biosciences' current ROA % is -61.87%. Based on the distribution chart, Caribou Biosciences ranks #1025 out of 1419 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Caribou Biosciences has a GF Score™ of 66/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Caribou Biosciences' ROA % compare to YDES and PRQR?
According to the Biotechnology industry distribution chart, Caribou Biosciences ranks #1025 out of 1419 companies for ROA %. This places Caribou Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Caribou Biosciences and its competitors. Caribou Biosciences's current ROA % is -61.87%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Caribou Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Caribou Biosciences (CRBU) is currently considered Fairly Valued. The stock's GF Value™ is $1.70, compared to a current price of $1.67 — trading 1.8% below its estimated fair value. The current ROA % is -61.87%. Caribou Biosciences' overall GF Score™ is 66/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Caribou Biosciences (CRBU), the current ROA % is -61.87% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Caribou Biosciences (CRBU) Overvalued in 2026?

Based on GuruFocus' analysis, Caribou Biosciences stock appears to be undervalued. The current stock price of $1.67 is trading 1.8% below its estimated GF Value™ of $1.70. GuruFocus considers Caribou Biosciences to be Fairly Valued.

Key valuation signals for CRBU:

  • ROA %: -61.87%
  • GF Value™: $1.70 vs. price of $1.67 (1.8% below fair value)
  • GF Score™: 66/100 with 5 warning signs

No single metric tells the full story. See the CRBU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Caribou Biosciences Business Description

Address 2929 7th Street, Suite 105, Berkeley, CA, USA, 94710
Caribou Biosciences Inc is a clinical-stage Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company is focused on advancing two clinical-stage allogeneic CAR-T cell therapy product candidates for the treatment of patients with hematologic malignancies: Vispacabtagene regedleucel and CB-011. It operates in one reportable segment, which is the business of developing allogeneic CAR-T cell therapies. Geographically, it operates in the United States and the rest of the World, of which the United States derives the maximum revenue.
66GF Score

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ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.67
Price
$1.70
GF Value