Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Caribou BiosciencesCRBU -2.69%65 Net Debt Paydown Yield % is 0.10% as of Jul. 24, 2026, which is 17% below its 10-year median of 0.12. GuruFocus rates CRBU with a GF Score™ of 65/100 and a GF Value™ of $1.67 (Fairly Valued). The stock has 5 warning signs investors should review. Among 1,162 Biotechnology companies, Caribou Biosciences ranks better than 55.42% on this metric.
Net Debt Paydown Yield % is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. It is a measure of a company's willingness and ability to reduce its debt.
As of today, Caribou Biosciences's Net Debt Paydown Yield % was 0.10%.
Caribou Biosciences (NAS:CRBU) Net Debt Paydown Yield % Explanation
Net Debt Paydown Yield % is the change in average of four quarters of company's total debt over a company's market cap. Assuming the total value of a company remains that same, shareholder value is increased as debt is reduced. In other words, it is a measure of the willingness and ability of a firm's management to pay down debt. Companies that have high debt paydown yields indicate that they are more aggressive with paying down debt.
In the calculation of Net Debt Paydown Yield %, we use the reductions of TTM average total debt one-year-ago and TTM average total debt at present, divided by its Market Cap.
Caribou Biosciences Net Debt Paydown Yield % Related Terms
Caribou Biosciences Net Debt Paydown Yield % Historical Data
* Premium members only.
The historical data trend for Caribou Biosciences's Net Debt Paydown Yield % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Caribou Biosciences Net Debt Paydown Yield % Chart
CRBU vs YDES, PRQR, CRBP: Net Debt Paydown Yield % Comparison
For the Biotechnology subindustry, Caribou Biosciences's Net Debt Paydown Yield %, along with its competitors' market caps and Net Debt Paydown Yield % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Caribou Biosciences Net Debt Paydown Yield % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Caribou Biosciences's Net Debt Paydown Yield % distribution charts can be found below:
* The bar in red indicates where Caribou Biosciences's Net Debt Paydown Yield % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
* All the data are calculated by TTM values. Note that if a companies is traded in several exchanges, then we calculate the company level data for Net Debt Paydown Yield % using the primary share class stock data. The calculation result in definition page is for demonstration purpose only, and it's showing the share class level data. Therefore, the numbers in the calculation may differ from elsewhere if the stock is not a primary share.
What does a Net Debt Paydown Yield % of 0.10% mean?
Caribou Biosciences (CRBU) has a Net Debt Paydown Yield % of 0.10% as of Jul. 24, 2026. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on Caribou Biosciences and its competitors. This is 17% below median its historical median of 0.12. According to the industry distribution chart, Caribou Biosciences ranks #518 out of 1162 companies in the Biotechnology industry, placing it in the top 44.6%.
Is Caribou Biosciences' Net Debt Paydown Yield % too high?
Caribou Biosciences' current Net Debt Paydown Yield % of 0.10% is 17% below median its 10-year median of 0.12. The Biotechnology industry median Net Debt Paydown Yield % is 0.03. Caribou Biosciences' value of 0.10% is 233.3% above this industry median. Based on the distribution chart, Caribou Biosciences ranks #518 out of 1162 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Caribou Biosciences has a GF Score™ of 65/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Caribou Biosciences' Net Debt Paydown Yield % compare to YDES and PRQR?
According to the Biotechnology industry distribution chart, Caribou Biosciences ranks #518 out of 1162 companies for Net Debt Paydown Yield %. This puts Caribou Biosciences in the upper half of its industry. The industry median Net Debt Paydown Yield % is 0.03. Caribou Biosciences' value of 0.10% is 233.3% above this benchmark. While the company's 10-year median is 0.12 vs. the industry median of 0.03, Caribou Biosciences has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Debt Paydown Yield % for a Biotechnology company?
The median Net Debt Paydown Yield % among Biotechnology companies is 0.03, based on 1,162 companies in the industry. Companies in the top quartile (top 25%) have a Net Debt Paydown Yield % significantly above this median, while those in the bottom quartile fall well below. However, Net Debt Paydown Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Caribou Biosciences's current Net Debt Paydown Yield % of 0.10% is 233.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Debt Paydown Yield % mean?
A high Net Debt Paydown Yield % can signal that a stock is expensive relative to its fundamentals. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on Caribou Biosciences and its competitors. For the Biotechnology industry, the median Net Debt Paydown Yield % is 0.03 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Caribou Biosciences's current Net Debt Paydown Yield % is 0.10%, which is 17% below median its own 10-year median of 0.12. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Caribou Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Caribou Biosciences (CRBU) is currently considered Fairly Valued. The stock's GF Value™ is $1.67, compared to a current price of $1.59 — trading 5% below its estimated fair value. The current Net Debt Paydown Yield % is 0.10%, which is 17% below median its 10-year median of 0.12 and 233.3% above the Biotechnology industry median of 0.03. Caribou Biosciences' overall GF Score™ is 65/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Debt Paydown Yield % calculated?
Net Debt Paydown Yield % is calculated from a company's financial statements. For Caribou Biosciences (CRBU), the current Net Debt Paydown Yield % is 0.10% as of Jul. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Caribou Biosciences (CRBU) Overvalued in 2026?
Based on GuruFocus' analysis, Caribou Biosciences stock appears to be undervalued.
The current stock price of $1.59 is trading 5% below its estimated GF Value™ of $1.67.
GuruFocus considers Caribou Biosciences to be Fairly Valued.
Key valuation signals for CRBU:
Net Debt Paydown Yield %: 0.10% (17% below median its 10-year median of 0.12)
GF Value™: $1.67 vs. price of $1.59 (5% below fair value)
Industry Position: 233.3% above the Biotechnology median (#518 of 1162)
No single metric tells the full story. See the CRBU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Caribou Biosciences Inc is a clinical-stage Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company is focused on advancing two clinical-stage allogeneic CAR-T cell therapy product candidates for the treatment of patients with hematologic malignancies: Vispacabtagene regedleucel and CB-011. It operates in one reportable segment, which is the business of developing allogeneic CAR-T cell therapies. Geographically, it operates in the United States and the rest of the World, of which the United States derives the maximum revenue.
65GF Score
Get the complete analysis for CRBU
Net Debt Paydown Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
CRBU has been successfully added to your 
