CryoPortCYRX -2.27%72 Return-on-Tangible-Equity is -12.47% as of Mar. 2026. GuruFocus rates CYRX with a GF Score™ of 72/100 and a GF Value™ of $11.00 (Significantly Overvalued). The stock has 9 warning signs investors should review. Among 976 Transportation companies, CryoPort ranks better than 82.38% on this metric.
Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. CryoPort's annualized net income for the quarter that ended in Mar. 2026 was $-42.2 Mil. CryoPort's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $338.1 Mil. Therefore, CryoPort's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -12.47%.
The historical rank and industry rank for CryoPort's Return-on-Tangible-Equity or its related term are showing as below:
CYRX'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -775.06 Med: -49.37 Max: 27.21
Current: 23.6
During the past 13 years, CryoPort's highest Return-on-Tangible-Equity was 27.21%. The lowest was -775.06%. And the median was -49.37%.
CYRX's Return-on-Tangible-Equity is ranked better than 82.38% of 976
companies
in the Transportation industry
Industry Median: 8.97
vs CYRX: 23.60
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
CryoPort Return-on-Tangible-Equity Related Terms
CryoPort Return-on-Tangible-Equity Historical Data
* Premium members only.
The historical data trend for CryoPort's Return-on-Tangible-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
CYRX vs FWRD, RLGT, PAL: Return-on-Tangible-Equity Comparison
For the Integrated Freight & Logistics subindustry, CryoPort's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
CryoPort Return-on-Tangible-Equity vs Transportation Industry
For the Transportation industry and Industrials sector, CryoPort's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where CryoPort's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is four times the quarterly (Mar. 2026) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of -12.47% mean?
CryoPort (CYRX) has a Return-on-Tangible-Equity of -12.47% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on CryoPort and its competitors. According to the industry distribution chart, CryoPort ranks #172 out of 976 companies in the Transportation industry, placing it in the top 17.6%.
Is CryoPort's Return-on-Tangible-Equity too high?
CryoPort's current Return-on-Tangible-Equity is -12.47%. Based on the distribution chart, CryoPort ranks #172 out of 976 companies in the Transportation industry, which is in the top quartile — a strong position relative to peers. Overall, CryoPort has a GF Score™ of 72/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CryoPort's Return-on-Tangible-Equity compare to FWRD and RLGT?
According to the Transportation industry distribution chart, CryoPort ranks #172 out of 976 companies for Return-on-Tangible-Equity. This places CryoPort in the top 18% of its industry — outperforming the majority of peers. The industry median Return-on-Tangible-Equity is 8.97. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Transportation company?
The median Return-on-Tangible-Equity among Transportation companies is 8.97, based on 976 companies in the industry. Companies in the top quartile (top 25%) have a Return-on-Tangible-Equity significantly above this median, while those in the bottom quartile fall well below. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on CryoPort and its competitors. For the Transportation industry, the median Return-on-Tangible-Equity is 8.97 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. CryoPort's current Return-on-Tangible-Equity is -12.47%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CryoPort stock overvalued right now?
Based on GuruFocus' analysis, CryoPort (CYRX) is currently considered Significantly Overvalued. The stock's GF Value™ is $11.00, compared to a current price of $15.50 — trading 40.9% above its estimated fair value. The current Return-on-Tangible-Equity is -12.47%. CryoPort's overall GF Score™ is 72/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For CryoPort (CYRX), the current Return-on-Tangible-Equity is -12.47% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is CryoPort (CYRX) Overvalued in 2026?
Based on GuruFocus' analysis, CryoPort stock appears to be overvalued.
The current stock price of $15.50 is trading 40.9% above its estimated GF Value™ of $11.00.
GuruFocus considers CryoPort to be Significantly Overvalued.
Key valuation signals for CYRX:
Return-on-Tangible-Equity: -12.47%
GF Value™: $11.00 vs. price of $15.50 (40.9% above fair value)
No single metric tells the full story. See the CYRX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
CryoPort Inc is a provider of integrated, temperature-controlled supply chain solutions for the life sciences industry, with a focus on supporting the cell and gene therapy market. The company provides services such as temperature-controlled logistics, biostorage, bioservices, cryopreservation solutions, and cryogenic systems manufacturing. It operates through two reportable segments: Life Sciences Services and Life Sciences Products. It generates the majority of its revenue from the Life Sciences Services segment.
72GF Score
Get the complete analysis for CYRX
Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
CYRX has been successfully added to your 
