CYRX (CryoPort) ROE % Adjusted to Book Value: -9.20% (As of Mar. 2026)

CryoPort CYRX +5.42% 72 ROE % Adjusted to Book Value is -9.20% as of Mar. 2026. GuruFocus rates CYRX with a GF Score™ of 72/100 and a GF Value™ of $10.97 (Significantly Overvalued). The stock has 9 warning signs investors should review.

CryoPort's ROE % for the quarter that ended in Mar. 2026 was -8.46%. CryoPort's PB Ratio for the quarter that ended in Mar. 2026 was 0.92. CryoPort's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -9.20%.

CryoPort ROE % Adjusted to Book Value Related Terms

CryoPort ROE % Adjusted to Book Value Historical Data

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The historical data trend for CryoPort's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CryoPort ROE % Adjusted to Book Value Chart

CryoPort Annual Data

Trend

Mar16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

ROE % Adjusted to Book Value

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-11.57

-3.99

-11.62

-24.30

16.64

CryoPort Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
ROE % Adjusted to Book Value	Get a 7-Day Free Trial															-14.25	116.51	-5.40	-8.82	-9.20

CYRX vs RLGT, FWRD, PAL: ROE % Adjusted to Book Value Comparison

For the Integrated Freight & Logistics subindustry, CryoPort's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

CryoPort ROE % Adjusted to Book Value vs Transportation Industry

For the Transportation industry and Industrials sector, CryoPort's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where CryoPort's ROE % Adjusted to Book Value falls into.

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72GF Score

CryoPort Inc CYRX

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CryoPort ROE % Adjusted to Book Value Calculation

CryoPort's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value	=	ROE %	/	PB Ratio
	=	17.31%	/	1.04
	=	16.64%

CryoPort's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value	=	ROE %	/	PB Ratio
	=	-8.46%	/	0.92
	=	-9.20%

Frequently Asked Questions Learn more about ROE % Adjusted to Book Value →

What does a ROE % Adjusted to Book Value of -9.20% mean?

CryoPort (CYRX) has a ROE % Adjusted to Book Value of -9.20% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on CryoPort and its competitors.

Is CryoPort's ROE % Adjusted to Book Value too high?

CryoPort's current ROE % Adjusted to Book Value is -9.20%. Overall, CryoPort has a GF Score™ of 72/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.

How does CryoPort's ROE % Adjusted to Book Value compare to RLGT and FWRD?

CryoPort's ROE % Adjusted to Book Value of -9.20% can be compared against companies in the Transportation industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good ROE % Adjusted to Book Value for a Transportation company?

A good ROE % Adjusted to Book Value depends on the Transportation industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high ROE % Adjusted to Book Value mean?

A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on CryoPort and its competitors. CryoPort's current ROE % Adjusted to Book Value is -9.20%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is CryoPort stock overvalued right now?

Based on GuruFocus' analysis, CryoPort (CYRX) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.97, compared to a current price of $15.57 — trading 41.9% above its estimated fair value. The current ROE % Adjusted to Book Value is -9.20%. CryoPort's overall GF Score™ is 72/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is ROE % Adjusted to Book Value calculated?

ROE % Adjusted to Book Value is calculated from a company's financial statements. For CryoPort (CYRX), the current ROE % Adjusted to Book Value is -9.20% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CryoPort (CYRX) Overvalued in 2026?

Based on GuruFocus' analysis, CryoPort stock appears to be overvalued. The current stock price of $15.57 is trading 41.9% above its estimated GF Value™ of $10.97. GuruFocus considers CryoPort to be Significantly Overvalued.

Key valuation signals for CYRX:

ROE % Adjusted to Book Value: -9.20%
GF Value™: $10.97 vs. price of $15.57 (41.9% above fair value)
GF Score™: 72/100 with 9 warning signs

No single metric tells the full story. See the CYRX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

CryoPort Business Description

Industry Industrials Transportation

Comparable Companies RLGT FWRD PAL PSIG CRGO SFWL OZVN NCEW JANL LSH FDX UPS XTER:DHL OCSE:DSV XSWX:KNIN JBHT SZSE:002352 FDXFw CHRW EXPD

Other Exchanges CKX:Germany

Address 112 Westwood Place, Suite 350, Brentwood, TN, USA, 37027

Website https://www.cryoportinc.com

CryoPort Inc is a provider of integrated, temperature-controlled supply chain solutions for the life sciences industry, with a focus on supporting the cell and gene therapy market. The company provides services such as temperature-controlled logistics, biostorage, bioservices, cryopreservation solutions, and cryogenic systems manufacturing. It operates through two reportable segments: Life Sciences Services and Life Sciences Products. It generates the majority of its revenue from the Life Sciences Services segment.

72GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$15.57

Price

$10.97

GF Value

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