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Spero Therapeutics's revenue per share for the
three
months ended in Mar. 2026 was $0.01.
Spero Therapeutics's revenue per share for the trailing twelve months (TTM) ended in Mar. 2026 was $0.85.
Warning Sign:
Spero Therapeutics Inc revenue per share has been in decline over the past 3 years.
During the past 12 months, the average Revenue Per Share Growth Rate of Spero Therapeutics was 63.10% per year.
During the past 3 years, the average Revenue Per Share Growth Rate was -7.90% per year.
During the past 5 years, the average Revenue Per Share Growth Rate was 118.80% per year.
Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get other companies' revenue growth rate.
The historical rank and industry rank for Spero Therapeutics's Revenue per Share or its related term are showing as below:
SPRO'
s 3-Year Revenue Growth Rate Range Over the Past 10 Years
Min: -7.9 Med: 71.45 Max: 433.9
Current: -7.9
During the past 11 years, Spero Therapeutics's highest 3-Year average Revenue Per Share Growth Rate was 433.90% per year. The lowest was -7.90% per year. And the median was 71.45% per year.
SPRO's 3-Year Revenue Growth Rate is ranked worse than 63.46% of 769
companies
in the Biotechnology industry
Industry Median: 3
vs SPRO: -7.90
His favorite companies are stalwart, those growing between 10-20% a year.
Companies in cyclical industries may see their revenue fluctuate wildly in good years and bad years.
Be Aware
Revenue can be manipulated by changing the way how revenue is booked. Companies may book sales before the payment is received, or before the revenue is fully earned. These will be added to balance sheet items such as account payable or account receivables.
Spero Therapeutics Revenue per Share Related Terms
Spero Therapeutics Revenue per Share Historical Data
* Premium members only.
The historical data trend for Spero Therapeutics's Revenue per Share can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
SPRO vs ACRV, BSEM, RNTX: Revenue per Share Comparison
For the Biotechnology subindustry, Spero Therapeutics's PS Ratio, along with its competitors' market caps and PS Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Spero Therapeutics PS Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Spero Therapeutics's PS Ratio distribution charts can be found below:
* The bar in red indicates where Spero Therapeutics's PS Ratio falls into.
Revenue per Share is the amount of Revenue per outstanding share of the company's stock.
Also referred as sales, revenue is income that a company receives from its normal business activities, usually from the sale of goods and services to customers. Revenue is often referred to as the "top line" due to its position on the income statement at the very top.
Spero Therapeutics's Revenue Per Share for the fiscal year that ended in Dec. 2025 is calculated as
Revenue per Share for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.85
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Spero Therapeutics (SPRO) has a Revenue per Share of $0.85 as of Mar. 2026. Revenue per share equals the per-share value of a company's sales. View historical data on Spero Therapeutics and its competitors. According to the industry distribution chart, Spero Therapeutics ranks #488 out of 769 companies in the Biotechnology industry, placing it in the top 63.5%.
Is Spero Therapeutics' Revenue per Share too high?
Spero Therapeutics' current Revenue per Share is $0.85. The Biotechnology industry median Revenue per Share is 3.00. Spero Therapeutics' value of $0.85 is 71.7% below this industry median. Based on the distribution chart, Spero Therapeutics ranks #488 out of 769 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Spero Therapeutics has a GF Score™ of 65/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Spero Therapeutics' Revenue per Share compare to ACRV and BSEM?
According to the Biotechnology industry distribution chart, Spero Therapeutics ranks #488 out of 769 companies for Revenue per Share. This places Spero Therapeutics in the lower half of its industry. The industry median Revenue per Share is 3.00. Spero Therapeutics' value of $0.85 is 71.7% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Revenue per Share for a Biotechnology company?
The median Revenue per Share among Biotechnology companies is 3.00, based on 769 companies in the industry. Companies in the top quartile (top 25%) have a Revenue per Share significantly above this median, while those in the bottom quartile fall well below. However, Revenue per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Spero Therapeutics's current Revenue per Share of $0.85 is 71.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Revenue per Share mean?
A high Revenue per Share can signal that a stock is expensive relative to its fundamentals. Revenue per share equals the per-share value of a company's sales. View historical data on Spero Therapeutics and its competitors. For the Biotechnology industry, the median Revenue per Share is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Spero Therapeutics's current Revenue per Share is $0.85. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Spero Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Spero Therapeutics (SPRO) is currently considered Modestly Overvalued. The stock's GF Value™ is $1.05, compared to a current price of $1.27 — trading 20.5% above its estimated fair value. The current Revenue per Share is $0.85 and 71.7% below the Biotechnology industry median of 3.00. Spero Therapeutics' overall GF Score™ is 65/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Revenue per Share calculated?
Revenue per Share is calculated from a company's financial statements. For Spero Therapeutics (SPRO), the current Revenue per Share is $0.85 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Spero Therapeutics (SPRO) Overvalued in 2026?
Based on GuruFocus' analysis, Spero Therapeutics stock appears to be overvalued.
The current stock price of $1.27 is trading 20.5% above its estimated GF Value™ of $1.05.
GuruFocus considers Spero Therapeutics to be Modestly Overvalued.
Key valuation signals for SPRO:
Revenue per Share: $0.85
GF Value™: $1.05 vs. price of $1.27 (20.5% above fair value)
Industry Position: 71.7% below the Biotechnology median (#488 of 769)
No single metric tells the full story. See the SPRO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
65GF Score
Get the complete analysis for SPRO
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