HUMA (Humacyte) ROA %: -62.11% (As of Mar. 2026)


HUMA Humacyte Inc HUMA
23 GF Score
Price $0.71
! 6 Warning Signs
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What is Humacyte ROA %?

Humacyte HUMA -0.90% 23 ROA % is -62.11% as of Mar. 2026. GuruFocus rates HUMA with a GF Score™ of 23/100. The stock has 6 warning signs investors should review. Among 1,416 Biotechnology companies, Humacyte ranks worse than 77.4% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Humacyte's annualized Net Income for the quarter that ended in Mar. 2026 was $-70.48 Mil. Humacyte's average Total Assets over the quarter that ended in Mar. 2026 was $113.46 Mil. Therefore, Humacyte's annualized ROA % for the quarter that ended in Mar. 2026 was -62.11%.

The historical rank and industry rank for Humacyte's ROA % or its related term are showing as below:

HUMA' s ROA % Range Over the Past 10 Years
Min: -111.77   Med: -47.24   Max: -4.88
Current: -78.73

During the past 6 years, Humacyte's highest ROA % was -4.88%. The lowest was -111.77%. And the median was -47.24%.

HUMA's ROA % is ranked worse than
77.4% of 1416 companies
in the Biotechnology industry
Industry Median: -32.87 vs HUMA: -78.73

Humacyte  (NAS:HUMA) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-70.476/113.4615
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-70.476 / 1.98)*(1.98 / 113.4615)
=Net Margin %*Asset Turnover
=-3559.39 %*0.0175
=-62.11 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Humacyte ROA % Related Terms


Humacyte ROA % Historical Data

* Premium members only.

The historical data trend for Humacyte's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Humacyte ROA % Chart

Humacyte Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial -13.47 -4.88 -66.63 -111.77 -32.12

Humacyte Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 104.22 -99.97 -60.82 -95.46 -62.11

HUMA vs ORMP, EQ, NBP: ROA % Comparison

For the Biotechnology subindustry, Humacyte's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Humacyte ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Humacyte's ROA % distribution charts can be found below:

* The bar in red indicates where Humacyte's ROA % falls into.


HUMA
23GF Score
Humacyte Inc HUMA
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Humacyte ROA % Calculation

Humacyte's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-40.833/( (137.872+116.366)/ 2 )
=-40.833/127.119
=-32.12 %

Humacyte's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-70.476/( (116.366+110.557)/ 2 )
=-70.476/113.4615
=-62.11 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -62.11% mean?
Humacyte (HUMA) has a ROA % of -62.11% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Humacyte and its competitors. According to the industry distribution chart, Humacyte ranks #1096 out of 1416 companies in the Biotechnology industry, placing it in the top 77.4%.
Is Humacyte's ROA % too high?
Humacyte's current ROA % is -62.11%. Based on the distribution chart, Humacyte ranks #1096 out of 1416 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Humacyte has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does Humacyte's ROA % compare to ORMP and EQ?
According to the Biotechnology industry distribution chart, Humacyte ranks #1096 out of 1416 companies for ROA %. This places Humacyte in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Humacyte and its competitors. Humacyte's current ROA % is -62.11%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Humacyte stock overvalued right now?
Humacyte (HUMA) has a current ROA % of -62.11%. The current ROA % is -62.11%. Humacyte's overall GF Score™ is 23/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Humacyte (HUMA), the current ROA % is -62.11% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Humacyte Business Description

Address 2525 East North Carolina Highway 54, Durham, NC, USA, 27713
Humacyte Inc is developing a commercial-stage biotechnology platform to deliver universally implantable bioengineered human tissues and organs designed to improve the lives of patients and transform the practice of medicine. It develops and manufactures acellular tissues to treat a wide range of diseases, injuries, and chronic conditions. Company's pipeline includes Vascular Trauma, PAD, Dailysis, Acellular Tissue Engineered Vessels, Organ Systems, Advanced Tissue Constructs.
23GF Score

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