Oncolys BioPharma (TSE:4588) ROA %: 0.00% (As of Dec. 2025)

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TSE:4588 Oncolys BioPharma Inc TSE:4588
40 GF Score
Price 円2,522.00
GF Value 円363.33
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Oncolys BioPharma ROA %?

Oncolys BioPharma TSE:4588 -2.06% 40 ROA % is 0.00% as of Dec. 2025. GuruFocus rates TSE:4588 with a GF Score™ of 40/100 and a GF Value™ of 円363.33 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,416 Biotechnology companies, Oncolys BioPharma ranks better than 53.46% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Oncolys BioPharma's annualized Net Income for the quarter that ended in Dec. 2025 was 円0.00 Mil. Oncolys BioPharma's average Total Assets over the quarter that ended in Dec. 2025 was 円3,244.10 Mil. Therefore, Oncolys BioPharma's annualized ROA % for the quarter that ended in Dec. 2025 was 0.00%.

The historical rank and industry rank for Oncolys BioPharma's ROA % or its related term are showing as below:

TSE:4588' s ROA % Range Over the Past 10 Years
Min: -82.64   Med: -40.53   Max: -23.36
Current: -27.49

During the past 13 years, Oncolys BioPharma's highest ROA % was -23.36%. The lowest was -82.64%. And the median was -40.53%.

TSE:4588's ROA % is ranked better than
53.46% of 1416 companies
in the Biotechnology industry
Industry Median: -32.87 vs TSE:4588: -27.49

Oncolys BioPharma  (TSE:4588) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Dec. 2025 )
=Net Income/Total Assets
=0/3244.1035
=(Net Income / Revenue)*(Revenue / Total Assets)
=(0 / 0)*(0 / 3244.1035)
=Net Margin %*Asset Turnover
=N/A %*0
=0.00 %

Note: The Net Income data used here is four times the quarterly (Dec. 2025) net income data. The Revenue data used here is four times the quarterly (Dec. 2025) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Oncolys BioPharma ROA % Related Terms


Oncolys BioPharma ROA % Historical Data

* Premium members only.

The historical data trend for Oncolys BioPharma's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oncolys BioPharma ROA % Chart

Oncolys BioPharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -45.58 -33.10 -82.64 -64.31 -53.08

Oncolys BioPharma Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -117.77 -94.49 0.00 -36.50

TSE:4588 vs VRTX, REGN, ALNY: ROA % Comparison

For the Biotechnology subindustry, Oncolys BioPharma's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oncolys BioPharma ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oncolys BioPharma's ROA % distribution charts can be found below:

* The bar in red indicates where Oncolys BioPharma's ROA % falls into.


TSE:4588
40GF Score
Oncolys BioPharma Inc TSE:4588
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Oncolys BioPharma ROA % Calculation

Oncolys BioPharma's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-2058.049/( (3198.858+4555.879)/ 2 )
=-2058.049/3877.3685
=-53.08 %

Oncolys BioPharma's annualized ROA % for the quarter that ended in Dec. 2025 is calculated as:

ROA %=Net Income (Q: Dec. 2025 )/( (Total Assets (Q: Jun. 2025 )+Total Assets (Q: Dec. 2025 ))/ count )
=0/( (1932.328+4555.879)/ 2 )
=0/3244.1035
=0.00 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Dec. 2025) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of 0.00% mean?
Oncolys BioPharma (TSE:4588) has a ROA % of 0.00% as of Dec. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Oncolys BioPharma and its competitors. According to the industry distribution chart, Oncolys BioPharma ranks #659 out of 1416 companies in the Biotechnology industry, placing it in the top 46.5%.
Is Oncolys BioPharma's ROA % too high?
Oncolys BioPharma's current ROA % is 0.00%. Based on the distribution chart, Oncolys BioPharma ranks #659 out of 1416 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Oncolys BioPharma has a GF Score™ of 40/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Oncolys BioPharma's ROA % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oncolys BioPharma ranks #659 out of 1416 companies for ROA %. This puts Oncolys BioPharma in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Oncolys BioPharma and its competitors. Oncolys BioPharma's current ROA % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oncolys BioPharma stock overvalued right now?
Based on GuruFocus' analysis, Oncolys BioPharma (TSE:4588) is currently considered Significantly Overvalued. The stock's GF Value™ is 円363.33, compared to a current price of 円2,522.00 — trading 594.1% above its estimated fair value. The current ROA % is 0.00%. Oncolys BioPharma's overall GF Score™ is 40/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Oncolys BioPharma (TSE:4588), the current ROA % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oncolys BioPharma (TSE:4588) Overvalued in 2026?

Based on GuruFocus' analysis, Oncolys BioPharma stock appears to be overvalued. The current stock price of 円2,522.00 is trading 594.1% above its estimated GF Value™ of 円363.33. GuruFocus considers Oncolys BioPharma to be Significantly Overvalued.

Key valuation signals for TSE:4588:

  • ROA %: 0.00%
  • GF Value™: 円363.33 vs. price of 円2,522.00 (594.1% above fair value)
  • GF Score™: 40/100 with 5 warning signs

No single metric tells the full story. See the TSE:4588 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Oncolys BioPharma Business Description

Address 4-1-28 Toranomon, Toranomon Towers Office, Minato-ku, Tokyo, JPN, 105-0001
Oncolys BioPharma Inc develops pharmaceutical products. The company is a biopharmaceutical company focused on developing therapies for cancer treatment. Their product pipeline includes various drug candidates such as Telomelysin (OBP-301) and OBP-702, aimed at addressing unmet medical needs in oncology. The company targets healthcare providers and institutions involved in cancer care and research.
40GF Score

Get the complete analysis for TSE:4588

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,522.00
Price
円363.33
GF Value