PRME (Prime Medicine) Equity-to-Asset: 0.26 (As of Mar. 2026) — 64% Below Median

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PRME Prime Medicine Inc PRME
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What is Prime Medicine Equity-to-Asset?

Prime Medicine PRME -3.72% 25 Equity-to-Asset is 0.26 as of Mar. 2026, which is 64% below its 10-year median of 0.72. GuruFocus rates PRME with a GF Score™ of 25/100. The stock has 4 warning signs investors should review. Among 1,416 Biotechnology companies, Prime Medicine ranks worse than 80.51% on this metric.

Equity to Asset ratio is calculated as total stockholders equity divided by total asset. Prime Medicine's Total Stockholders Equity for the quarter that ended in Mar. 2026 was $76.70 Mil. Prime Medicine's Total Assets for the quarter that ended in Mar. 2026 was $294.73 Mil. Therefore, Prime Medicine's Equity to Asset Ratio for the quarter that ended in Mar. 2026 was 0.26.

The historical rank and industry rank for Prime Medicine's Equity-to-Asset or its related term are showing as below:

PRME' s Equity-to-Asset Range Over the Past 10 Years
Min: 0.22   Med: 0.72   Max: 0.88
Current: 0.26

During the past 6 years, the highest Equity to Asset Ratio of Prime Medicine was 0.88. The lowest was 0.22. And the median was 0.72.

PRME's Equity-to-Asset is ranked worse than
80.51% of 1416 companies
in the Biotechnology industry
Industry Median: 0.68 vs PRME: 0.26

Prime Medicine  (NAS:PRME) Equity-to-Asset Explanation

Equity to Asset ratio can vary greatly across different industries, as they have different capital structure. A company with smaller Equity to Asset ratio (more leveraged) may have higher ROE % because of the leverage.

For banks, the required minimum Equity to Asset ratio by regulation is 5%. Some stronger banks may have Equity to Asset Ratio of more than 10%.


Prime Medicine Equity-to-Asset Related Terms


Prime Medicine Equity-to-Asset Historical Data

* Premium members only.

The historical data trend for Prime Medicine's Equity-to-Asset can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Prime Medicine Equity-to-Asset Chart

Prime Medicine Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Equity-to-Asset
Get a 7-Day Free Trial 0.79 0.88 0.69 0.52 0.35

Prime Medicine Quarterly Data
Dec20 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Equity-to-Asset Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.33 0.22 0.42 0.35 0.26

PRME vs EIKN, CRMD, STTK: Equity-to-Asset Comparison

For the Biotechnology subindustry, Prime Medicine's Equity-to-Asset, along with its competitors' market caps and Equity-to-Asset data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Prime Medicine Equity-to-Asset vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Prime Medicine's Equity-to-Asset distribution charts can be found below:

* The bar in red indicates where Prime Medicine's Equity-to-Asset falls into.


PRME
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Prime Medicine Inc PRME
Equity-to-Asset is just one metric. See GF Score™, valuation, warning signs, and more.
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Prime Medicine Equity-to-Asset Calculation

Equity to Asset ratio measures the ratios of the portion of the asset owned by shareholders out of the total asset. It indicates the leverage of the company, and the amount of debt the company uses in its operation.

Equity to Asset ratio is calculated by dividing total stockholders equity by total asset.

Prime Medicine's Equity to Asset Ratio for the fiscal year that ended in Dec. 2025 is calculated as

Equity to Asset (A: Dec. 2025 )=Total Stockholders Equity/Total Assets
=120.868/342.733
=0.35

Prime Medicine's Equity to Asset Ratio for the quarter that ended in Mar. 2026 is calculated as

Equity to Asset (Q: Mar. 2026 )=Total Stockholders Equity/Total Assets
=76.7/294.73
=0.26

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Equity-to-Asset →
What does a Equity-to-Asset of 0.26 mean?
Prime Medicine (PRME) has a Equity-to-Asset of 0.26 as of Mar. 2026. Equity-to-asset ratio equals total company equity divided by total assets. It measures financial leverage. View historical data on Prime Medicine and its competitors. This is 64% below median its historical median of 0.72. Over the past decade, Prime Medicine's Equity-to-Asset has ranged from 0.22 to 0.88. According to the industry distribution chart, Prime Medicine ranks #1140 out of 1416 companies in the Biotechnology industry, placing it in the top 80.5%.
Is Prime Medicine's Equity-to-Asset too high?
Prime Medicine's current Equity-to-Asset of 0.26 is 64% below median its 10-year median of 0.72. Over the past 10 years, this metric has ranged from a low of 0.22 to a high of 0.88. The Biotechnology industry median Equity-to-Asset is 0.68. Prime Medicine's value of 0.26 is 61.8% below this industry median. Based on the distribution chart, Prime Medicine ranks #1140 out of 1416 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Prime Medicine has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Prime Medicine's Equity-to-Asset compare to EIKN and CRMD?
According to the Biotechnology industry distribution chart, Prime Medicine ranks #1140 out of 1416 companies for Equity-to-Asset. This places Prime Medicine in the lower half of its industry. The industry median Equity-to-Asset is 0.68. Prime Medicine's value of 0.26 is 61.8% below this benchmark. Historically, Prime Medicine's own Equity-to-Asset has ranged from 0.22 to 0.88 over the past decade. While the company's 10-year median is 0.72 vs. the industry median of 0.68, Prime Medicine has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Equity-to-Asset for a Biotechnology company?
The median Equity-to-Asset among Biotechnology companies is 0.68, based on 1,416 companies in the industry. Companies in the top quartile (top 25%) have a Equity-to-Asset significantly above this median, while those in the bottom quartile fall well below. However, Equity-to-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Prime Medicine's current Equity-to-Asset of 0.26 is 61.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Equity-to-Asset mean?
A high Equity-to-Asset can signal that a stock is expensive relative to its fundamentals. Equity-to-asset ratio equals total company equity divided by total assets. It measures financial leverage. View historical data on Prime Medicine and its competitors. For the Biotechnology industry, the median Equity-to-Asset is 0.68 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Prime Medicine's current Equity-to-Asset is 0.26, which is 64% below median its own 10-year median of 0.72. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prime Medicine stock overvalued right now?
Prime Medicine (PRME) has a current Equity-to-Asset of 0.26. The current Equity-to-Asset is 0.26, which is 64% below median its 10-year median of 0.72 and 61.8% below the Biotechnology industry median of 0.68. Prime Medicine's overall GF Score™ is 25/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Equity-to-Asset calculated?
Equity-to-Asset is calculated from a company's financial statements. For Prime Medicine (PRME), the current Equity-to-Asset is 0.26 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Prime Medicine Business Description

Address 60 First Street, Cambridge, MA, USA, 02141
Prime Medicine Inc is a biotechnology company focused on developing a new class of genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its program, PM577 for Wilson Disease, is designed to initially correct the H1069Q mutation in the ATP7B gene and is supported by preclinical data showing targeted correction and restoration of copper homeostasis in animal models. In addition, PM647 is being developed for alpha-1 antitrypsin deficiency, or AATD, another liver targeted disease with substantial unmet need.
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