ISCO (International Stem Cell) Book Value per Share: $-0.53 (As of Mar. 2026)

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ISCO International Stem Cell Corp ISCO
30 GF Score
Price $0.27
GF Value $0.13
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is International Stem Cell Book Value per Share?

International Stem Cell ISCO +2.31% 30 Book Value per Share is $-0.53 as of Mar. 2026. GuruFocus rates ISCO with a GF Score™ of 30/100 and a GF Value™ of $0.13 (Significantly Overvalued). The stock has 6 warning signs investors should review.

International Stem Cell's book value per share for the quarter that ended in Mar. 2026 was $-0.53.

During the past 3 years, the average Book Value Per Share Growth Rate was 3.50% per year. During the past 5 years, the average Book Value Per Share Growth Rate was 3.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the book value growth rate using book value per share data.

During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of International Stem Cell was 129.20% per year. The lowest was -69.20% per year. And the median was 3.25% per year.

International Stem Cell's current price is $0.266. Its book value per share for the quarter that ended in Mar. 2026 was $-0.53. Hence, today's PB Ratio of International Stem Cell is .

During the past 13 years, the highest P/B Ratio of International Stem Cell was 15.95. The lowest was 1.16. And the median was 4.35.


International Stem Cell  (OTCPK:ISCO) Book Value per Share Explanation

Usually a company's book value and Tangible Book per Share may not reflect its true value. The assets may be carried on the balance sheets at the original cost minus depreciation. This may underestimate the true economic values of the assets. It also may over-estimate their true economic value because the assets can become obsolete.

For financial companies such as banks and insurance companies, their assets may be reported in current market value of the assets owned. Book values of financial companies are more accurate indicator of the economic value of the company.


International Stem Cell Book Value per Share Related Terms


International Stem Cell Book Value per Share Historical Data

* Premium members only.

The historical data trend for International Stem Cell's Book Value per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

International Stem Cell Book Value per Share Chart

International Stem Cell Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Book Value per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.57 -0.57 -0.52 -0.49 -0.51

International Stem Cell Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Book Value per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.51 -0.49 -0.47 -0.51 -0.53

ISCO vs GRI, VRAX, PKTX: Book Value per Share Comparison

For the Biotechnology subindustry, International Stem Cell's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


International Stem Cell PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, International Stem Cell's PB Ratio distribution charts can be found below:

* The bar in red indicates where International Stem Cell's PB Ratio falls into.


ISCO
30GF Score
International Stem Cell Corp ISCO
Book Value per Share is just one metric. See GF Score™, valuation, warning signs, and more.
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International Stem Cell Book Value per Share Calculation

International Stem Cell's Book Value Per Share for the fiscal year that ended in Dec. 2025 is calculated as:

Book Value Per Share=(Total Stockholders Equity-Preferred Stock)/Shares Outstanding (EOP)
=(-4.06-0.01)/8.00
=-0.51

International Stem Cell's Book Value Per Share for the quarter that ended in Mar. 2026 is calculated as:

Book Value Per Share=(Total Stockholders Equity-Preferred Stock)/Shares Outstanding (EOP)
=(-4.22-0.01)/8.00
=-0.53

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Theoretically it is what the shareholders will receive if the company is liquidated. Total Stockholders Equity is a balance sheet item and equal to Total Assets less Total Liabilities of the company.

Book value may include intangible items which may come from the company's past acquisitions. Book value less intangibles is called Tangible Book.

Frequently Asked Questions Learn more about Book Value per Share →
What does a Book Value per Share of $-0.53 mean?
International Stem Cell (ISCO) has a Book Value per Share of $-0.53 as of Mar. 2026. Book value per share gives the per-share value of a company's stockholder equity. View historical data on International Stem Cell and its competitors.
Is International Stem Cell's Book Value per Share too high?
International Stem Cell's current Book Value per Share is $-0.53. Overall, International Stem Cell has a GF Score™ of 30/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does International Stem Cell's Book Value per Share compare to GRI and VRAX?
International Stem Cell's Book Value per Share of $-0.53 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Book Value per Share for a Biotechnology company?
A good Book Value per Share depends on the Biotechnology industry context. However, Book Value per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Book Value per Share mean?
A high Book Value per Share can signal that a stock is expensive relative to its fundamentals. Book value per share gives the per-share value of a company's stockholder equity. View historical data on International Stem Cell and its competitors. International Stem Cell's current Book Value per Share is $-0.53. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is International Stem Cell stock overvalued right now?
Based on GuruFocus' analysis, International Stem Cell (ISCO) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.13, compared to a current price of $0.27 — trading 104.6% above its estimated fair value. The current Book Value per Share is $-0.53. International Stem Cell's overall GF Score™ is 30/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Book Value per Share calculated?
Book Value per Share is calculated from a company's financial statements. For International Stem Cell (ISCO), the current Book Value per Share is $-0.53 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is International Stem Cell (ISCO) Overvalued in 2026?

Based on GuruFocus' analysis, International Stem Cell stock appears to be overvalued. The current stock price of $0.27 is trading 104.6% above its estimated GF Value™ of $0.13. GuruFocus considers International Stem Cell to be Significantly Overvalued.

Key valuation signals for ISCO:

  • Book Value per Share: $-0.53
  • GF Value™: $0.13 vs. price of $0.27 (104.6% above fair value)
  • GF Score™: 30/100 with 6 warning signs

No single metric tells the full story. See the ISCO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


International Stem Cell Business Description

Address 9745 Businesspark Avenue, San Diego, CA, USA, 92131
International Stem Cell Corp is a clinical-stage biotechnology company. It is focused on therapeutic and biomedical product development with multiple long-term therapeutic opportunities. The company develops different cell types from its stem cells that may result in therapeutic products. The clinical applications of the company include neural stem cells for the treatment of Parkinson's disease and other central nervous system disorders; Liver cells, which are used to treat a variety of congenital and acquired liver diseases; and retinal cells and three-dimensional eye structures. The company operates in three segments, the therapeutic market, the biomedical market, and the anti-aging market. The Biomedical products business segment accounts for the majority of revenue.
30GF Score

Get the complete analysis for ISCO

Book Value per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.27
Price
$0.13
GF Value