ISCO (International Stem Cell) FCF Margin %: 3.89% (As of Mar. 2026)


ISCO International Stem Cell Corp ISCO
28 GF Score
Price $0.18
GF Value $0.13
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is International Stem Cell FCF Margin %?

International Stem Cell ISCO +4.76% 28 FCF Margin % is 3.89% as of Mar. 2026. GuruFocus rates ISCO with a GF Score™ of 28/100 and a GF Value™ of $0.13 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 959 Biotechnology companies, International Stem Cell ranks better than 73.72% on this metric.

FCF Margin % is calculated as Free Cash Flow divided by its Revenue. International Stem Cell's Free Cash Flow for the three months ended in Mar. 2026 was $0.09 Mil. International Stem Cell's Revenue for the three months ended in Mar. 2026 was $2.32 Mil. Therefore, International Stem Cell's FCF Margin % for the quarter that ended in Mar. 2026 was 3.89%.

As of today, International Stem Cell's current FCF Yield % is -11.85%.

The historical rank and industry rank for International Stem Cell's FCF Margin % or its related term are showing as below:

ISCO' s FCF Margin % Range Over the Past 10 Years
Min: -71.75   Med: -11.01   Max: 10.86
Current: -1.82


During the past 13 years, the highest FCF Margin % of International Stem Cell was 10.86%. The lowest was -71.75%. And the median was -11.01%.

ISCO's FCF Margin % is ranked better than
73.72% of 959 companies
in the Biotechnology industry
Industry Median: -84.65 vs ISCO: -1.82


International Stem Cell FCF Margin % Related Terms


International Stem Cell FCF Margin % Historical Data

* Premium members only.

The historical data trend for International Stem Cell's FCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

International Stem Cell FCF Margin % Chart

International Stem Cell Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
FCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -18.70 3.92 10.86 -1.74 -0.41

International Stem Cell Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
FCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 10.43 -13.57 1.94 1.25 3.89

ISCO vs ONCO, VRAX, LYRA: FCF Margin % Comparison

For the Biotechnology subindustry, International Stem Cell's FCF Margin %, along with its competitors' market caps and FCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


International Stem Cell FCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, International Stem Cell's FCF Margin % distribution charts can be found below:

* The bar in red indicates where International Stem Cell's FCF Margin % falls into.


ISCO
28GF Score
International Stem Cell Corp ISCO
FCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

International Stem Cell FCF Margin % Calculation

FCF margin is the ratio of Free Cash Flow divided by net sales or Revenue, usually presented in percent.

International Stem Cell's FCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

FCF Margin=Free Cash Flow (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-0.037/9.1
=-0.41 %

International Stem Cell's FCF Margin for the quarter that ended in Mar. 2026 is calculated as

FCF Margin=Free Cash Flow (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=0.09/2.315
=3.89 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about FCF Margin % →
What does a FCF Margin % of 3.89% mean?
International Stem Cell (ISCO) has a FCF Margin % of 3.89% as of Mar. 2026. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on International Stem Cell and its competitors. According to the industry distribution chart, International Stem Cell ranks #252 out of 959 companies in the Biotechnology industry, placing it in the top 26.3%.
Is International Stem Cell's FCF Margin % too high?
International Stem Cell's current FCF Margin % is 3.89%. Based on the distribution chart, International Stem Cell ranks #252 out of 959 companies in the Biotechnology industry, which is above the industry midpoint. Overall, International Stem Cell has a GF Score™ of 28/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does International Stem Cell's FCF Margin % compare to ONCO and VRAX?
According to the Biotechnology industry distribution chart, International Stem Cell ranks #252 out of 959 companies for FCF Margin %. This puts International Stem Cell in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good FCF Margin % for a Biotechnology company?
A good FCF Margin % depends on the Biotechnology industry context. However, FCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high FCF Margin % mean?
A high FCF Margin % can signal that a stock is expensive relative to its fundamentals. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on International Stem Cell and its competitors. International Stem Cell's current FCF Margin % is 3.89%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is International Stem Cell stock overvalued right now?
Based on GuruFocus' analysis, International Stem Cell (ISCO) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.13, compared to a current price of $0.18 — trading 37% above its estimated fair value. The current FCF Margin % is 3.89%. International Stem Cell's overall GF Score™ is 28/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is FCF Margin % calculated?
FCF Margin % is calculated from a company's financial statements. For International Stem Cell (ISCO), the current FCF Margin % is 3.89% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is International Stem Cell (ISCO) Overvalued in 2026?

Based on GuruFocus' analysis, International Stem Cell stock appears to be overvalued. The current stock price of $0.18 is trading 37% above its estimated GF Value™ of $0.13. GuruFocus considers International Stem Cell to be Significantly Overvalued.

Key valuation signals for ISCO:

  • FCF Margin %: 3.89%
  • GF Value™: $0.13 vs. price of $0.18 (37% above fair value)
  • GF Score™: 28/100 with 4 warning signs

No single metric tells the full story. See the ISCO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


International Stem Cell Business Description

Address 9745 Businesspark Avenue, San Diego, CA, USA, 92131
International Stem Cell Corp is a clinical-stage biotechnology company. It is focused on therapeutic and biomedical product development with multiple long-term therapeutic opportunities. The company develops different cell types from its stem cells that may result in therapeutic products. The clinical applications of the company include neural stem cells for the treatment of Parkinson's disease and other central nervous system disorders; Liver cells, which are used to treat a variety of congenital and acquired liver diseases; and retinal cells and three-dimensional eye structures. The company operates in three segments, the therapeutic market, the biomedical market, and the anti-aging market. The Biomedical products business segment accounts for the majority of revenue.
28GF Score

Get the complete analysis for ISCO

FCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.18
Price
$0.13
GF Value