ISCO (International Stem Cell) OCF Margin %: 5.23% (As of Mar. 2026)


ISCO International Stem Cell Corp ISCO
24 GF Score
Price $0.18
GF Value $0.13
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is International Stem Cell OCF Margin %?

International Stem Cell ISCO -10.50% 24 OCF Margin % is 5.23% as of Mar. 2026. GuruFocus rates ISCO with a GF Score™ of 24/100 and a GF Value™ of $0.13 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 949 Biotechnology companies, International Stem Cell ranks better than 67.54% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. International Stem Cell's Cash Flow from Operations for the three months ended in Mar. 2026 was $0.12 Mil. International Stem Cell's Revenue for the three months ended in Mar. 2026 was $2.32 Mil. Therefore, International Stem Cell's OCF Margin % for the quarter that ended in Mar. 2026 was 5.23%.

As of today, International Stem Cell's current OCF Yield % is -6.84%.

The historical rank and industry rank for International Stem Cell's OCF Margin % or its related term are showing as below:

ISCO' s OCF Margin % Range Over the Past 10 Years
Min: -58.58   Med: -7.27   Max: 11.93
Current: -1.06


During the past 13 years, the highest OCF Margin % of International Stem Cell was 11.93%. The lowest was -58.58%. And the median was -7.27%.

ISCO's OCF Margin % is ranked better than
67.54% of 949 companies
in the Biotechnology industry
Industry Median: -64.23 vs ISCO: -1.06


International Stem Cell OCF Margin % Related Terms


International Stem Cell OCF Margin % Historical Data

* Premium members only.

The historical data trend for International Stem Cell's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

International Stem Cell OCF Margin % Chart

International Stem Cell Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -18.07 4.06 11.93 0.14 0.09

International Stem Cell Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 10.66 -12.26 2.07 1.48 5.23

ISCO vs ZVSA, AXIM, HEPA: OCF Margin % Comparison

For the Biotechnology subindustry, International Stem Cell's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


International Stem Cell OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, International Stem Cell's OCF Margin % distribution charts can be found below:

* The bar in red indicates where International Stem Cell's OCF Margin % falls into.


ISCO
24GF Score
International Stem Cell Corp ISCO
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

International Stem Cell OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

International Stem Cell's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=0.008/9.1
=0.09 %

International Stem Cell's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=0.121/2.315
=5.23 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of 5.23% mean?
International Stem Cell (ISCO) has a OCF Margin % of 5.23% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on International Stem Cell and its competitors. According to the industry distribution chart, International Stem Cell ranks #308 out of 949 companies in the Biotechnology industry, placing it in the top 32.5%.
Is International Stem Cell's OCF Margin % too high?
International Stem Cell's current OCF Margin % is 5.23%. Based on the distribution chart, International Stem Cell ranks #308 out of 949 companies in the Biotechnology industry, which is above the industry midpoint. Overall, International Stem Cell has a GF Score™ of 24/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does International Stem Cell's OCF Margin % compare to ZVSA and AXIM?
According to the Biotechnology industry distribution chart, International Stem Cell ranks #308 out of 949 companies for OCF Margin %. This puts International Stem Cell in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on International Stem Cell and its competitors. International Stem Cell's current OCF Margin % is 5.23%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is International Stem Cell stock overvalued right now?
Based on GuruFocus' analysis, International Stem Cell (ISCO) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.13, compared to a current price of $0.18 — trading 37.7% above its estimated fair value. The current OCF Margin % is 5.23%. International Stem Cell's overall GF Score™ is 24/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For International Stem Cell (ISCO), the current OCF Margin % is 5.23% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is International Stem Cell (ISCO) Overvalued in 2026?

Based on GuruFocus' analysis, International Stem Cell stock appears to be overvalued. The current stock price of $0.18 is trading 37.7% above its estimated GF Value™ of $0.13. GuruFocus considers International Stem Cell to be Significantly Overvalued.

Key valuation signals for ISCO:

  • OCF Margin %: 5.23%
  • GF Value™: $0.13 vs. price of $0.18 (37.7% above fair value)
  • GF Score™: 24/100 with 6 warning signs

No single metric tells the full story. See the ISCO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


International Stem Cell Business Description

Address 9745 Businesspark Avenue, San Diego, CA, USA, 92131
International Stem Cell Corp is a clinical-stage biotechnology company. It is focused on therapeutic and biomedical product development with multiple long-term therapeutic opportunities. The company develops different cell types from its stem cells that may result in therapeutic products. The clinical applications of the company include neural stem cells for the treatment of Parkinson's disease and other central nervous system disorders; Liver cells, which are used to treat a variety of congenital and acquired liver diseases; and retinal cells and three-dimensional eye structures. The company operates in three segments, the therapeutic market, the biomedical market, and the anti-aging market. The Biomedical products business segment accounts for the majority of revenue.
24GF Score

Get the complete analysis for ISCO

OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.18
Price
$0.13
GF Value