XLO (Xilio Therapeutics) Buyback Yield %: -63.07 (As of Jul. 26, 2026)

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XLO Xilio Therapeutics Inc XLO
32 GF Score
Price $8.64
! 2 Warning Signs
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What is Xilio Therapeutics Buyback Yield %?

Xilio Therapeutics XLO +1.05% 32 Buyback Yield % is -63.07 as of Jul. 26, 2026. GuruFocus rates XLO with a GF Score™ of 32/100. The stock has 2 warning signs investors should review. Among 738 Biotechnology companies, Xilio Therapeutics ranks worse than 85.64% on this metric.

Buyback yield is the net repurchase of shares outstanding over the market capital of the company. It is a measure of shareholder return.

Xilio Therapeutics's current buyback yield was -63.07%.


Xilio Therapeutics Buyback Yield % Historical Data

* Premium members only.

The historical data trend for Xilio Therapeutics's Buyback Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xilio Therapeutics Buyback Yield % Chart

Xilio Therapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Buyback Yield %
Get a 7-Day Free Trial -26.58 0.00 0.00 -15.62 -100.11

Xilio Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Buyback Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -19.58 -147.98 29.04 -100.11 -73.67

XLO vs FLNA, BSEM, BOLD: Buyback Yield % Comparison

For the Biotechnology subindustry, Xilio Therapeutics's Buyback Yield %, along with its competitors' market caps and Buyback Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xilio Therapeutics Buyback Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xilio Therapeutics's Buyback Yield % distribution charts can be found below:

* The bar in red indicates where Xilio Therapeutics's Buyback Yield % falls into.


XLO
32GF Score
Xilio Therapeutics Inc XLO
Buyback Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xilio Therapeutics Buyback Yield % Calculation

Buyback yield is a measure of shareholder return.

Xilio Therapeutics's Buyback Yield for the fiscal year that ended in Dec. 2025 is calculated as

Buyback Yield=Net Issuance of Stock / Market Cap
=- (Repurchase of Stock + Issuance of Stock) / Market Cap
=- (0 + 40.655) / 40.6104468
=-100.11%

Xilio Therapeutics's annualized Buyback Yield for the quarter that ended in Mar. 2026 is calculated as

Buyback Yield=Net Issuance of Stock(TTM) / Market Cap
=- (Repurchase of Stock + Issuance of Stock) (TTM)** / Market Cap
=- (0 + 35.828) / 48.63503
=-73.67%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** If the quarter corresponds to the year-end period, we will use the annual Repurchase of Stock and Issuance of Stock data .

Frequently Asked Questions Learn more about Buyback Yield % →
What does a Buyback Yield % of -63.07 mean?
Xilio Therapeutics (XLO) has a Buyback Yield % of -63.07 as of Jul. 26, 2026. Share buyback yield equals the net issuance of stock divided by market cap. View historical data on Xilio Therapeutics and its competitors. According to the industry distribution chart, Xilio Therapeutics ranks #632 out of 738 companies in the Biotechnology industry, placing it in the top 85.6%.
Is Xilio Therapeutics' Buyback Yield % too high?
Xilio Therapeutics' current Buyback Yield % is -63.07. Based on the distribution chart, Xilio Therapeutics ranks #632 out of 738 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Xilio Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Xilio Therapeutics' Buyback Yield % compare to FLNA and BSEM?
According to the Biotechnology industry distribution chart, Xilio Therapeutics ranks #632 out of 738 companies for Buyback Yield %. This places Xilio Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Buyback Yield % for a Biotechnology company?
A good Buyback Yield % depends on the Biotechnology industry context. However, Buyback Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Buyback Yield % mean?
A high Buyback Yield % can signal that a stock is expensive relative to its fundamentals. Share buyback yield equals the net issuance of stock divided by market cap. View historical data on Xilio Therapeutics and its competitors. Xilio Therapeutics's current Buyback Yield % is -63.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xilio Therapeutics stock overvalued right now?
Xilio Therapeutics (XLO) has a current Buyback Yield % of -63.07. The current Buyback Yield % is -63.07. Xilio Therapeutics' overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Buyback Yield % calculated?
Buyback Yield % is calculated from a company's financial statements. For Xilio Therapeutics (XLO), the current Buyback Yield % is -63.07 as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Xilio Therapeutics Business Description

Address 828 Winter Street, Suite 300, Waltham, MA, USA, 02451
Xilio Therapeutics Inc is a clinical-stage biotechnology company focused on discovering and developing masked immuno-oncology (I-O) therapies to improve outcomes for people living with cancer. Leveraging its clinically validated masking technology and capabilities, the company develops I-O therapies designed to selectively activate within the tumor microenvironment to achieve durable efficacy without the severe side effects associated with systemically active I-O agents. Its integrated biology and protein engineering approach enables the design and development of potent masked biologics that are activated by tumor-specific proteases.
32GF Score

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Buyback Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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