XLO (Xilio Therapeutics) FCF Margin %: -181.05% (As of Mar. 2026)

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XLO Xilio Therapeutics Inc XLO
32 GF Score
Price $8.64
! 2 Warning Signs
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What is Xilio Therapeutics FCF Margin %?

Xilio Therapeutics XLO +1.05% 32 FCF Margin % is -181.05% as of Mar. 2026. GuruFocus rates XLO with a GF Score™ of 32/100. The stock has 2 warning signs investors should review. Among 950 Biotechnology companies, Xilio Therapeutics ranks worse than 53.47% on this metric.

FCF Margin % is calculated as Free Cash Flow divided by its Revenue. Xilio Therapeutics's Free Cash Flow for the three months ended in Mar. 2026 was $-22.90 Mil. Xilio Therapeutics's Revenue for the three months ended in Mar. 2026 was $12.65 Mil. Therefore, Xilio Therapeutics's FCF Margin % for the quarter that ended in Mar. 2026 was -181.05%.

As of today, Xilio Therapeutics's current FCF Yield % is -100.98%.

The historical rank and industry rank for Xilio Therapeutics's FCF Margin % or its related term are showing as below:

XLO' s FCF Margin % Range Over the Past 10 Years
Min: -290.26   Med: -151.43   Max: -12.59
Current: -107.26

During the past 7 years, the highest FCF Margin % of Xilio Therapeutics was -12.59%. The lowest was -290.26%. And the median was -151.43%.

XLO's FCF Margin % is ranked worse than
53.47% of 950 companies
in the Biotechnology industry
Industry Median: -81.28 vs XLO: -107.26

Xilio Therapeutics FCF Margin % Related Terms

Xilio Therapeutics FCF Margin % Historical Data

* Premium members only.

The historical data trend for Xilio Therapeutics's FCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xilio Therapeutics FCF Margin % Chart

Xilio Therapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
FCF Margin %
Get a 7-Day Free Trial 0.00 0.00 0.00 -290.26 -12.59

Xilio Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
FCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 988.26 -184.04 -91.76 -15.29 -181.05

XLO vs FLNA, BSEM, BOLD: FCF Margin % Comparison

For the Biotechnology subindustry, Xilio Therapeutics's FCF Margin %, along with its competitors' market caps and FCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Xilio Therapeutics FCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xilio Therapeutics's FCF Margin % distribution charts can be found below:

* The bar in red indicates where Xilio Therapeutics's FCF Margin % falls into.


XLO
32GF Score
Xilio Therapeutics Inc XLO
FCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xilio Therapeutics FCF Margin % Calculation

FCF margin is the ratio of Free Cash Flow divided by net sales or Revenue, usually presented in percent.

Xilio Therapeutics's FCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

FCF Margin=Free Cash Flow (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-5.51/43.766
=-12.59 %

Xilio Therapeutics's FCF Margin for the quarter that ended in Mar. 2026 is calculated as

FCF Margin=Free Cash Flow (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-22.899/12.648
=-181.05 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about FCF Margin % →
What does a FCF Margin % of -181.05% mean?
Xilio Therapeutics (XLO) has a FCF Margin % of -181.05% as of Mar. 2026. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on Xilio Therapeutics and its competitors. According to the industry distribution chart, Xilio Therapeutics ranks #508 out of 950 companies in the Biotechnology industry, placing it in the top 53.5%.
Is Xilio Therapeutics' FCF Margin % too high?
Xilio Therapeutics' current FCF Margin % is -181.05%. Based on the distribution chart, Xilio Therapeutics ranks #508 out of 950 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Xilio Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Xilio Therapeutics' FCF Margin % compare to FLNA and BSEM?
According to the Biotechnology industry distribution chart, Xilio Therapeutics ranks #508 out of 950 companies for FCF Margin %. This places Xilio Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good FCF Margin % for a Biotechnology company?
A good FCF Margin % depends on the Biotechnology industry context. However, FCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high FCF Margin % mean?
A high FCF Margin % can signal that a stock is expensive relative to its fundamentals. Free cash flow margin is the ratio of total free cash flow to net sales. View historical data on Xilio Therapeutics and its competitors. Xilio Therapeutics's current FCF Margin % is -181.05%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xilio Therapeutics stock overvalued right now?
Xilio Therapeutics (XLO) has a current FCF Margin % of -181.05%. The current FCF Margin % is -181.05%. Xilio Therapeutics' overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is FCF Margin % calculated?
FCF Margin % is calculated from a company's financial statements. For Xilio Therapeutics (XLO), the current FCF Margin % is -181.05% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Xilio Therapeutics Business Description

Address 828 Winter Street, Suite 300, Waltham, MA, USA, 02451
Xilio Therapeutics Inc is a clinical-stage biotechnology company focused on discovering and developing masked immuno-oncology (I-O) therapies to improve outcomes for people living with cancer. Leveraging its clinically validated masking technology and capabilities, the company develops I-O therapies designed to selectively activate within the tumor microenvironment to achieve durable efficacy without the severe side effects associated with systemically active I-O agents. Its integrated biology and protein engineering approach enables the design and development of potent masked biologics that are activated by tumor-specific proteases.
32GF Score

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FCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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