XLO (Xilio Therapeutics) Market Cap: $56.81 Mil (As of Jul. 26, 2026)

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XLO Xilio Therapeutics Inc XLO
32 GF Score
Price $8.64
! 2 Warning Signs
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What is Xilio Therapeutics Market Cap?

Xilio Therapeutics XLO +1.05% 32 Market Cap is $56.81 Mil as of Jul. 26, 2026. GuruFocus rates XLO with a GF Score™ of 32/100. The stock has 2 warning signs investors should review. Among 1,422 Biotechnology companies, Xilio Therapeutics ranks worse than 60.34% on this metric.

Market cap is the total market value to buy the whole company. It is equal to the share price times the number of Shares Outstanding (EOP). Xilio Therapeutics's share price for the quarter that ended in Mar. 2026 was $8.41. Xilio Therapeutics's Shares Outstanding (EOP) for the quarter that ended in Mar. 2026 was 5.78 Mil. Therefore, Xilio Therapeutics's market cap for the quarter that ended in Mar. 2026 was $48.64 Mil.

Xilio Therapeutics's quarterly market cap declined from Sep. 2025 ($43.68 Mil) to Dec. 2025 ($40.61 Mil) but then increased from Dec. 2025 ($40.61 Mil) to Mar. 2026 ($48.64 Mil).

Xilio Therapeutics's annual market cap increased from Dec. 2023 ($15.18 Mil) to Dec. 2024 ($43.69 Mil) but then declined from Dec. 2024 ($43.69 Mil) to Dec. 2025 ($40.61 Mil).

Enterprise Value is the theoretical takeover price. It is more comprehensive than market capitalization (market cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash and cash equivalents. Xilio Therapeutics's Enterprise Value for Today is $-86.89 Mil.


Xilio Therapeutics  (NAS:XLO) Market Cap Explanation

Market cap is not the real price you pay for a company. If you buy the company and become its owner, you become the owner of the cash the company has, and you also assume the company’s debt. The real price you pay is the Enterprise Value.

Warren Buffett uses the ratio of total market cap of all public traded companies over GDP to measure if the market is expensive. As of April 2012, the US total market cap is about $14.7 trillion, while the US GDP is about $15 trillion. The market was modestly overvalued.


Xilio Therapeutics Market Cap Related Terms


Xilio Therapeutics Market Cap Historical Data

* Premium members only.

The historical data trend for Xilio Therapeutics's Market Cap can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xilio Therapeutics Market Cap Chart

Xilio Therapeutics Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Market Cap
Get a 7-Day Free Trial 437.70 73.78 15.18 43.69 40.61

Xilio Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Market Cap Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 37.50 35.24 43.68 40.61 48.64

XLO vs FLNA, BSEM, BOLD: Market Cap Comparison

For the Biotechnology subindustry, Xilio Therapeutics's Market Cap, along with its competitors' market caps and Market Cap data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xilio Therapeutics Market Cap vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xilio Therapeutics's Market Cap distribution charts can be found below:

* The bar in red indicates where Xilio Therapeutics's Market Cap falls into.


XLO
32GF Score
Xilio Therapeutics Inc XLO
Market Cap is just one metric. See GF Score™, valuation, warning signs, and more.
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Xilio Therapeutics Market Cap Calculation

Market cap is the short version of market capitalization. It is the total market value to buy the whole company. It is equal to the share price times the number of shares outstanding.

Xilio Therapeutics's Market Cap for the fiscal year that ended in Dec. 2025 is calculated as

Market Cap (A: Dec. 2025 )=Share Price (A: Dec. 2025 )*Shares Outstanding (EOP) (A: Dec. 2025 )
=$8.9628*4.531
=$40.61

Xilio Therapeutics's Market Cap for the quarter that ended in Mar. 2026 is calculated as

Market Cap (Q: Mar. 2026 )=Share Price (Q: Mar. 2026 )*Shares Outstanding (EOP) (Q: Mar. 2026 )
=$8.41*5.783
=$48.64

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Market Cap →
What does a Market Cap of $56.81 Mil mean?
Xilio Therapeutics (XLO) has a Market Cap of $56.81 Mil as of Jul. 26, 2026. Market cap equals the total value of a company's shares: price times shares outstanding. View historical data on Xilio Therapeutics and its competitors. According to the industry distribution chart, Xilio Therapeutics ranks #858 out of 1422 companies in the Biotechnology industry, placing it in the top 60.3%.
Is Xilio Therapeutics' Market Cap too high?
Xilio Therapeutics' current Market Cap is $56.81 Mil. The Biotechnology industry median Market Cap is 110.94. Xilio Therapeutics' value of $56.81 Mil is 48.8% below this industry median. Based on the distribution chart, Xilio Therapeutics ranks #858 out of 1422 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Xilio Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Xilio Therapeutics' Market Cap compare to FLNA and BSEM?
According to the Biotechnology industry distribution chart, Xilio Therapeutics ranks #858 out of 1422 companies for Market Cap. This places Xilio Therapeutics in the lower half of its industry. The industry median Market Cap is 110.94. Xilio Therapeutics' value of $56.81 Mil is 48.8% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Market Cap for a Biotechnology company?
The median Market Cap among Biotechnology companies is 110.94, based on 1,422 companies in the industry. Companies in the top quartile (top 25%) have a Market Cap significantly above this median, while those in the bottom quartile fall well below. However, Market Cap should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Xilio Therapeutics's current Market Cap of $56.81 Mil is 48.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Market Cap mean?
A high Market Cap can signal that a stock is expensive relative to its fundamentals. Market cap equals the total value of a company's shares: price times shares outstanding. View historical data on Xilio Therapeutics and its competitors. For the Biotechnology industry, the median Market Cap is 110.94 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Xilio Therapeutics's current Market Cap is $56.81 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xilio Therapeutics stock overvalued right now?
Xilio Therapeutics (XLO) has a current Market Cap of $56.81 Mil. The current Market Cap is $56.81 Mil and 48.8% below the Biotechnology industry median of 110.94. Xilio Therapeutics' overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Market Cap calculated?
Market Cap is calculated from a company's financial statements. For Xilio Therapeutics (XLO), the current Market Cap is $56.81 Mil as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Xilio Therapeutics Business Description

Address 828 Winter Street, Suite 300, Waltham, MA, USA, 02451
Xilio Therapeutics Inc is a clinical-stage biotechnology company focused on discovering and developing masked immuno-oncology (I-O) therapies to improve outcomes for people living with cancer. Leveraging its clinically validated masking technology and capabilities, the company develops I-O therapies designed to selectively activate within the tumor microenvironment to achieve durable efficacy without the severe side effects associated with systemically active I-O agents. Its integrated biology and protein engineering approach enables the design and development of potent masked biologics that are activated by tumor-specific proteases.
32GF Score

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$8.64
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