Protagonist Therapeutics (MEX:PTGX) Cyclically Adjusted Book per Share: MXN101.73 (As of Mar. 2026)


MEX:PTGX Protagonist Therapeutics Inc MEX:PTGX
47 GF Score
Price MXN1,565.33
GF Value MXN751.22
! 7 Warning Signs
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What is Protagonist Therapeutics Cyclically Adjusted Book per Share?

Protagonist Therapeutics MEX:PTGX 47 Cyclically Adjusted Book per Share is MXN101.73 as of Mar. 2026. GuruFocus rates MEX:PTGX with a GF Score™ of 47/100 and a GF Value™ of MXN751.22. The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Protagonist Therapeutics's adjusted book value per share for the three months ended in Mar. 2026 was MXN184.034. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN101.73 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Protagonist Therapeutics's average Cyclically Adjusted Book Growth Rate was 18.50% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

As of today (2026-07-12), Protagonist Therapeutics's current stock price is MXN1565.33. Protagonist Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was MXN101.73. Protagonist Therapeutics's Cyclically Adjusted PB Ratio of today is 15.39.

During the past 12 years, the highest Cyclically Adjusted PB Ratio of Protagonist Therapeutics was 19.21. The lowest was 6.58. And the median was 9.85.


Protagonist Therapeutics  (MEX:PTGX) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Protagonist Therapeutics's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=1565.33/101.73
=15.39

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 12 years, the highest Cyclically Adjusted PB Ratio of Protagonist Therapeutics was 19.21. The lowest was 6.58. And the median was 9.85.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Protagonist Therapeutics Cyclically Adjusted Book per Share Related Terms


Protagonist Therapeutics Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Protagonist Therapeutics's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagonist Therapeutics Cyclically Adjusted Book per Share Chart

Protagonist Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 114.52

Protagonist Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 110.74 114.52 101.73

MEX:PTGX vs IMVT, SYRE, MIRM: Cyclically Adjusted Book per Share Comparison

For the Biotechnology subindustry, Protagonist Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagonist Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagonist Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Protagonist Therapeutics's Cyclically Adjusted PB Ratio falls into.


MEX:PTGX
47GF Score
Protagonist Therapeutics Inc MEX:PTGX
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Protagonist Therapeutics Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Protagonist Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=184.034/330.2130*330.2130
=184.034

Current CPI (Mar. 2026) = 330.2130.

Protagonist Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 -52.345 241.018 -71.717
201609 112.785 241.428 154.262
201612 107.949 241.432 147.645
201703 83.765 243.801 113.454
201706 65.281 244.955 88.002
201709 61.946 246.819 82.876
201712 112.346 246.524 150.485
201803 98.393 249.554 130.195
201806 99.708 251.989 130.660
201809 96.057 252.439 125.651
201812 95.279 251.233 125.232
201903 83.606 254.202 108.606
201906 64.868 256.143 83.626
201909 69.196 256.759 88.992
201912 55.409 256.974 71.201
202003 53.559 258.115 68.519
202006 105.046 257.797 134.554
202009 100.400 260.280 127.376
202012 127.144 260.474 161.185
202103 120.646 264.877 150.405
202106 149.715 271.696 181.960
202109 142.190 274.310 171.168
202112 128.656 278.802 152.380
202203 123.758 287.504 142.142
202206 110.738 296.311 123.408
202209 99.604 296.808 110.814
202212 85.196 296.797 94.788
202303 75.745 301.836 82.866
202306 87.687 305.109 94.902
202309 91.299 307.789 97.951
202312 99.029 306.746 106.605
202403 158.722 312.332 167.809
202406 168.767 314.175 177.382
202409 175.961 315.301 184.283
202412 230.749 315.605 241.429
202503 227.628 319.799 235.041
202506 202.522 322.561 207.326
202509 189.601 324.800 192.761
202512 176.871 324.054 180.233
202603 184.034 330.213 184.034

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of MXN101.73 mean?
Protagonist Therapeutics (MEX:PTGX) has a Cyclically Adjusted Book per Share of MXN101.73 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Protagonist Therapeutics and its competitors.
Is Protagonist Therapeutics' Cyclically Adjusted Book per Share too high?
Protagonist Therapeutics' current Cyclically Adjusted Book per Share is MXN101.73. Overall, Protagonist Therapeutics has a GF Score™ of 47/100, reflecting its overall financial health beyond just this single metric.
How does Protagonist Therapeutics' Cyclically Adjusted Book per Share compare to IMVT and SYRE?
Protagonist Therapeutics' Cyclically Adjusted Book per Share of MXN101.73 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Biotechnology company?
A good Cyclically Adjusted Book per Share depends on the Biotechnology industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Protagonist Therapeutics and its competitors. Protagonist Therapeutics's current Cyclically Adjusted Book per Share is MXN101.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagonist Therapeutics stock overvalued right now?
Protagonist Therapeutics (MEX:PTGX) has a current Cyclically Adjusted Book per Share of MXN101.73. The stock's GF Value™ is MXN751.22, compared to a current price of MXN1,565.33 — trading 108.4% above its estimated fair value. The current Cyclically Adjusted Book per Share is MXN101.73. Protagonist Therapeutics' overall GF Score™ is 47/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Protagonist Therapeutics (MEX:PTGX), the current Cyclically Adjusted Book per Share is MXN101.73 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Protagonist Therapeutics (MEX:PTGX) Overvalued in 2026?

Based on GuruFocus' analysis, Protagonist Therapeutics stock appears to be overvalued. The current stock price of MXN1,565.33 is trading 108.4% above its estimated GF Value™ of MXN751.22.

Key valuation signals for MEX:PTGX:

  • Cyclically Adjusted Book per Share: MXN101.73
  • GF Value™: MXN751.22 vs. price of MXN1,565.33 (108.4% above fair value)
  • GF Score™: 47/100 with 7 warning signs

No single metric tells the full story. See the MEX:PTGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Protagonist Therapeutics Business Description

Other Exchanges PTGX:USA
Address 7707 Gateway Boulevard, Suite 140, Newark, CA, USA, 94560
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
47GF Score

Get the complete analysis for MEX:PTGX

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,565.33
Price
MXN751.22
GF Value