Protagonist Therapeutics (MEX:PTGX) EV-to-EBIT: 159.41 (As of Aug. 28, 2026)

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MEX:PTGX Protagonist Therapeutics Inc MEX:PTGX
53 GF Score
Price MXN1,565.33
GF Value MXN958.05
! 6 Warning Signs
View Full Analysis

What is Protagonist Therapeutics EV-to-EBIT?

Protagonist Therapeutics MEX:PTGX 53 EV-to-EBIT is 159.41 as of Aug. 28, 2026. GuruFocus rates MEX:PTGX with a GF Score™ of 53/100 and a GF Value™ of MXN958.05. The stock has 6 warning signs investors should review. Among 380 Biotechnology companies, Protagonist Therapeutics ranks worse than 95% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Protagonist Therapeutics's Enterprise Value is MXN150,844 Mil. Protagonist Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was MXN946 Mil. Therefore, Protagonist Therapeutics's EV-to-EBIT for today is 159.41.

The historical rank and industry rank for Protagonist Therapeutics's EV-to-EBIT or its related term are showing as below:

MEX:PTGX' s EV-to-EBIT Range Over the Past 10 Years
Min: -56.53   Med: -3.31   Max: 290.16
Current: 152.5

During the past 12 years, the highest EV-to-EBIT of Protagonist Therapeutics was 290.16. The lowest was -56.53. And the median was -3.31.

MEX:PTGX's EV-to-EBIT is ranked worse than
95% of 380 companies
in the Biotechnology industry
Industry Median: 15.99 vs MEX:PTGX: 152.50

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Protagonist Therapeutics's Enterprise Value for the quarter that ended in Jun. 2026 was MXN87,739 Mil. Protagonist Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 was MXN946 Mil. Protagonist Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 was 1.08%.


Protagonist Therapeutics  (MEX:PTGX) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Protagonist Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Jun. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Jun. 2026 ) =EBIT / Enterprise Value (Q: Jun. 2026 )
=946.292/87738.66276
=1.08 %

Protagonist Therapeutics's Enterprise Value for the quarter that ended in Jun. 2026 was MXN87,739 Mil.
Protagonist Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN946 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Protagonist Therapeutics EV-to-EBIT Related Terms


Protagonist Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Protagonist Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagonist Therapeutics EV-to-EBIT Chart

Protagonist Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -10.45 -2.32 -10.49 7.70 -31.04

Protagonist Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 119.85 188.50 -31.04 -43.74 122.62

MEX:PTGX vs CRNX, SYRE, TGTX: EV-to-EBIT Comparison

For the Biotechnology subindustry, Protagonist Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagonist Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagonist Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Protagonist Therapeutics's EV-to-EBIT falls into.


MEX:PTGX
53GF Score
Protagonist Therapeutics Inc MEX:PTGX
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Protagonist Therapeutics EV-to-EBIT Calculation

Protagonist Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=150843.756/946.292
=159.41

Protagonist Therapeutics's current Enterprise Value is MXN150,844 Mil.
Protagonist Therapeutics's EBIT for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was MXN946 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of 159.41 mean?
Protagonist Therapeutics (MEX:PTGX) has a EV-to-EBIT of 159.41 as of Aug. 28, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Protagonist Therapeutics and its competitors. According to the industry distribution chart, Protagonist Therapeutics ranks #361 out of 380 companies in the Biotechnology industry, placing it in the top 95%.
Is Protagonist Therapeutics' EV-to-EBIT too high?
Protagonist Therapeutics' current EV-to-EBIT is 159.41. The Biotechnology industry median EV-to-EBIT is 15.99. Protagonist Therapeutics' value of 159.41 is 896.9% above this industry median. Based on the distribution chart, Protagonist Therapeutics ranks #361 out of 380 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Protagonist Therapeutics has a GF Score™ of 53/100, reflecting its overall financial health beyond just this single metric.
How does Protagonist Therapeutics' EV-to-EBIT compare to CRNX and SYRE?
According to the Biotechnology industry distribution chart, Protagonist Therapeutics ranks #361 out of 380 companies for EV-to-EBIT. This places Protagonist Therapeutics in the lower half of its industry. The industry median EV-to-EBIT is 15.99. Protagonist Therapeutics' value of 159.41 is 896.9% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 15.99, based on 380 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Protagonist Therapeutics's current EV-to-EBIT of 159.41 is 896.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Protagonist Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 15.99 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Protagonist Therapeutics's current EV-to-EBIT is 159.41. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagonist Therapeutics stock overvalued right now?
Protagonist Therapeutics (MEX:PTGX) has a current EV-to-EBIT of 159.41. The stock's GF Value™ is MXN958.05, compared to a current price of MXN1,565.33 — trading 63.4% above its estimated fair value. The current EV-to-EBIT is 159.41 and 896.9% above the Biotechnology industry median of 15.99. Protagonist Therapeutics' overall GF Score™ is 53/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Protagonist Therapeutics (MEX:PTGX), the current EV-to-EBIT is 159.41 as of Aug. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Protagonist Therapeutics (MEX:PTGX) Overvalued in 2026?

Based on GuruFocus' analysis, Protagonist Therapeutics stock appears to be overvalued. The current stock price of MXN1,565.33 is trading 63.4% above its estimated GF Value™ of MXN958.05.

Key valuation signals for MEX:PTGX:

  • EV-to-EBIT: 159.41
  • GF Value™: MXN958.05 vs. price of MXN1,565.33 (63.4% above fair value)
  • GF Score™: 53/100 with 6 warning signs
  • Industry Position: 896.9% above the Biotechnology median (#361 of 380)

No single metric tells the full story. See the MEX:PTGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Protagonist Therapeutics Business Description

Other Exchanges PTGX:USA
Address 7707 Gateway Boulevard, Suite 140, Newark, CA, USA, 94560
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
53GF Score

Get the complete analysis for MEX:PTGX

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,565.33
Price
MXN958.05
GF Value