Protagonist Therapeutics (MEX:PTGX) ROE % Adjusted to Book Value: 0.28% (As of Mar. 2026)


MEX:PTGX Protagonist Therapeutics Inc MEX:PTGX
47 GF Score
Price MXN1,565.33
GF Value MXN751.22
! 7 Warning Signs
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What is Protagonist Therapeutics ROE % Adjusted to Book Value?

Protagonist Therapeutics MEX:PTGX 47 ROE % Adjusted to Book Value is 0.28% as of Mar. 2026. GuruFocus rates MEX:PTGX with a GF Score™ of 47/100 and a GF Value™ of MXN751.22. The stock has 7 warning signs investors should review.

Protagonist Therapeutics's ROE % for the quarter that ended in Mar. 2026 was 2.38%. Protagonist Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 8.51. Protagonist Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was 0.28%.


Protagonist Therapeutics ROE % Adjusted to Book Value Related Terms


Protagonist Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Protagonist Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagonist Therapeutics ROE % Adjusted to Book Value Chart

Protagonist Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -2.11

Protagonist Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 -3.72 -3.15 0.28

MEX:PTGX vs IMVT, SYRE, MIRM: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Protagonist Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagonist Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagonist Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Protagonist Therapeutics's ROE % Adjusted to Book Value falls into.


MEX:PTGX
47GF Score
Protagonist Therapeutics Inc MEX:PTGX
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Protagonist Therapeutics ROE % Adjusted to Book Value Calculation

Protagonist Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-18.63% / 8.85
=-2.11%

Protagonist Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=2.38% / 8.51
=0.28%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 0.28% mean?
Protagonist Therapeutics (MEX:PTGX) has a ROE % Adjusted to Book Value of 0.28% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Protagonist Therapeutics and its competitors.
Is Protagonist Therapeutics' ROE % Adjusted to Book Value too high?
Protagonist Therapeutics' current ROE % Adjusted to Book Value is 0.28%. Overall, Protagonist Therapeutics has a GF Score™ of 47/100, reflecting its overall financial health beyond just this single metric.
How does Protagonist Therapeutics' ROE % Adjusted to Book Value compare to IMVT and SYRE?
Protagonist Therapeutics' ROE % Adjusted to Book Value of 0.28% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Protagonist Therapeutics and its competitors. Protagonist Therapeutics's current ROE % Adjusted to Book Value is 0.28%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagonist Therapeutics stock overvalued right now?
Protagonist Therapeutics (MEX:PTGX) has a current ROE % Adjusted to Book Value of 0.28%. The stock's GF Value™ is MXN751.22, compared to a current price of MXN1,565.33 — trading 108.4% above its estimated fair value. The current ROE % Adjusted to Book Value is 0.28%. Protagonist Therapeutics' overall GF Score™ is 47/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Protagonist Therapeutics (MEX:PTGX), the current ROE % Adjusted to Book Value is 0.28% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Protagonist Therapeutics (MEX:PTGX) Overvalued in 2026?

Based on GuruFocus' analysis, Protagonist Therapeutics stock appears to be overvalued. The current stock price of MXN1,565.33 is trading 108.4% above its estimated GF Value™ of MXN751.22.

Key valuation signals for MEX:PTGX:

  • ROE % Adjusted to Book Value: 0.28%
  • GF Value™: MXN751.22 vs. price of MXN1,565.33 (108.4% above fair value)
  • GF Score™: 47/100 with 7 warning signs

No single metric tells the full story. See the MEX:PTGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Protagonist Therapeutics Business Description

Other Exchanges PTGX:USA
Address 7707 Gateway Boulevard, Suite 140, Newark, CA, USA, 94560
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
47GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,565.33
Price
MXN751.22
GF Value