Protagonist Therapeutics (MEX:PTGX) E10: MXN-29.26 (As of Mar. 2026)


MEX:PTGX Protagonist Therapeutics Inc MEX:PTGX
47 GF Score
Price MXN1,565.33
GF Value MXN751.22
! 7 Warning Signs
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What is Protagonist Therapeutics E10?

Protagonist Therapeutics MEX:PTGX 47 E10 is MXN-29.26 as of Mar. 2026. GuruFocus rates MEX:PTGX with a GF Score™ of 47/100 and a GF Value™ of MXN751.22. The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Protagonist Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was MXN0.902. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is MXN-29.26 for the trailing ten years ended in Mar. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-07-12), Protagonist Therapeutics's current stock price is MXN1565.33. Protagonist Therapeutics's E10 for the quarter that ended in Mar. 2026 was MXN-29.26. Protagonist Therapeutics's Shiller PE Ratio of today is .


Protagonist Therapeutics  (MEX:PTGX) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Protagonist Therapeutics E10 Related Terms


Protagonist Therapeutics E10 Historical Data

* Premium members only.

The historical data trend for Protagonist Therapeutics's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Protagonist Therapeutics E10 Chart

Protagonist Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -39.61

Protagonist Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 -41.39 -39.61 -29.26

MEX:PTGX vs IMVT, SYRE, MIRM: E10 Comparison

For the Biotechnology subindustry, Protagonist Therapeutics's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Protagonist Therapeutics Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Protagonist Therapeutics's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Protagonist Therapeutics's Shiller PE Ratio falls into.


MEX:PTGX
47GF Score
Protagonist Therapeutics Inc MEX:PTGX
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Protagonist Therapeutics E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Protagonist Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.902/330.2130*330.2130
=0.902

Current CPI (Mar. 2026) = 330.2130.

Protagonist Therapeutics Quarterly Data

per share eps CPI Adj_EPS
201606 -8.296 241.018 -11.366
201609 -16.822 241.428 -23.008
201612 -13.813 241.432 -18.892
201703 -15.816 243.801 -21.422
201706 -16.088 244.955 -21.688
201709 -5.263 246.819 -7.041
201712 -2.946 246.524 -3.946
201803 -6.540 249.554 -8.654
201806 -8.056 251.989 -10.557
201809 -7.108 252.439 -9.298
201812 -11.192 251.233 -14.710
201903 -11.251 254.202 -14.615
201906 -22.667 256.143 -29.222
201909 -12.043 256.759 -15.488
201912 -11.882 256.974 -15.268
202003 -16.883 258.115 -21.599
202006 -13.618 257.797 -17.443
202009 -4.639 260.280 -5.885
202012 -9.548 260.474 -12.104
202103 -11.038 264.877 -13.761
202106 -13.735 271.696 -16.693
202109 -14.393 274.310 -17.326
202112 -15.796 278.802 -18.709
202203 -8.562 287.504 -9.834
202206 -16.899 296.311 -18.832
202209 -12.874 296.808 -14.323
202212 -13.452 296.797 -14.967
202303 -12.077 301.836 -13.212
202306 -11.658 305.109 -12.617
202309 -10.103 307.789 -10.839
202312 7.469 306.746 8.040
202403 54.104 312.332 57.201
202406 -9.160 314.175 -9.628
202409 -10.633 315.301 -11.136
202412 41.294 315.605 43.205
202503 -3.887 319.799 -4.014
202506 -10.356 322.561 -10.602
202509 -11.373 324.800 -11.563
202512 -12.424 324.054 -12.660
202603 0.902 330.213 0.902

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of MXN-29.26 mean?
Protagonist Therapeutics (MEX:PTGX) has a E10 of MXN-29.26 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Protagonist Therapeutics and its competitors.
Is Protagonist Therapeutics' E10 too high?
Protagonist Therapeutics' current E10 is MXN-29.26. Overall, Protagonist Therapeutics has a GF Score™ of 47/100, reflecting its overall financial health beyond just this single metric.
How does Protagonist Therapeutics' E10 compare to IMVT and SYRE?
Protagonist Therapeutics' E10 of MXN-29.26 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Protagonist Therapeutics and its competitors. Protagonist Therapeutics's current E10 is MXN-29.26. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Protagonist Therapeutics stock overvalued right now?
Protagonist Therapeutics (MEX:PTGX) has a current E10 of MXN-29.26. The stock's GF Value™ is MXN751.22, compared to a current price of MXN1,565.33 — trading 108.4% above its estimated fair value. The current E10 is MXN-29.26. Protagonist Therapeutics' overall GF Score™ is 47/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Protagonist Therapeutics (MEX:PTGX), the current E10 is MXN-29.26 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Protagonist Therapeutics (MEX:PTGX) Overvalued in 2026?

Based on GuruFocus' analysis, Protagonist Therapeutics stock appears to be overvalued. The current stock price of MXN1,565.33 is trading 108.4% above its estimated GF Value™ of MXN751.22.

Key valuation signals for MEX:PTGX:

  • E10: MXN-29.26
  • GF Value™: MXN751.22 vs. price of MXN1,565.33 (108.4% above fair value)
  • GF Score™: 47/100 with 7 warning signs

No single metric tells the full story. See the MEX:PTGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Protagonist Therapeutics Business Description

Other Exchanges PTGX:USA
Address 7707 Gateway Boulevard, Suite 140, Newark, CA, USA, 94560
Protagonist Therapeutics Inc is a biopharmaceutical company engaged in the discovery and development of peptide-based therapeutics using its proprietary technology platform. The company focuses on three therapeutic areas: inflammation and immunology, hematology, and metabolic diseases. Its pipeline includes clinical-stage and preclinical candidates such as rusfertide for polycythemia vera, icotrokinra for inflammatory diseases, and other programs targeting IL-17, obesity, and iron metabolism disorders, developed through internal research and strategic collaborations.
47GF Score

Get the complete analysis for MEX:PTGX

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,565.33
Price
MXN751.22
GF Value