Ono Pharmaceutical Co (TSE:4528) Cyclically Adjusted Book per Share: 円1,436.33 (As of Mar. 2026)

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TSE:4528 Ono Pharmaceutical Co Ltd TSE:4528
89 GF Score
Price 円2,400.50
GF Value 円2,239.11
Valuation Fairly Valued
! 4 Warning Signs
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What is Ono Pharmaceutical Co Cyclically Adjusted Book per Share?

Ono Pharmaceutical Co TSE:4528 -1.13% 89 Cyclically Adjusted Book per Share is 円1,436.33 as of Mar. 2026. GuruFocus rates TSE:4528 with a GF Score™ of 89/100 and a GF Value™ of 円2,239.11 (Fairly Valued). The stock has 4 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

Ono Pharmaceutical Co's adjusted book value per share for the three months ended in Mar. 2026 was 円1,810.416. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円1,436.33 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Ono Pharmaceutical Co's average Cyclically Adjusted Book Growth Rate was 6.80% per year. During the past 3 years, the average Cyclically Adjusted Book Growth Rate was 8.60% per year. During the past 5 years, the average Cyclically Adjusted Book Growth Rate was 8.60% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the Cyclically Adjusted Book Growth Rate using Cyclically Adjusted Book per Share data.

During the past 13 years, the highest 3-Year average Cyclically Adjusted Book Growth Rate of Ono Pharmaceutical Co was 9.40% per year. The lowest was 4.40% per year. And the median was 7.60% per year.

As of today (2026-07-14), Ono Pharmaceutical Co's current stock price is 円2400.50. Ono Pharmaceutical Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was 円1,436.33. Ono Pharmaceutical Co's Cyclically Adjusted PB Ratio of today is 1.67.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Ono Pharmaceutical Co was 3.91. The lowest was 1.12. And the median was 2.58.


Ono Pharmaceutical Co  (TSE:4528) Cyclically Adjusted Book per Share Explanation

If a company grows much fast than inflation, Cyclically Adjusted Book per Share may underestimate the company's equity. Cyclically Adjusted PB Ratio can seem to be too high even the actual PB Ratio is low.

For the Cyclically Adjusted PB Ratio, the book value of the past 10 years are inflation-adjusted and averaged. The result is used for P/B calculation. Since it looks at the average over the last 10 years, the Cyclically Adjusted PB Ratio is also called CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Ono Pharmaceutical Co's Cyclically Adjusted PB Ratio of today is calculated as

Cyclically Adjusted PB Ratio=Share Price/Cyclically Adjusted Book per Share
=2400.50/1436.33
=1.67

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Cyclically Adjusted PB Ratio of Ono Pharmaceutical Co was 3.91. The lowest was 1.12. And the median was 2.58.


Be Aware

Cyclically Adjusted PB Ratio works better for cyclical companies. It gives you a better idea on the company's real book value.


Ono Pharmaceutical Co Cyclically Adjusted Book per Share Related Terms


Ono Pharmaceutical Co Cyclically Adjusted Book per Share Historical Data

* Premium members only.

The historical data trend for Ono Pharmaceutical Co's Cyclically Adjusted Book per Share can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co Cyclically Adjusted Book per Share Chart

Ono Pharmaceutical Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted Book per Share
Get a 7-Day Free Trial Premium Member Only Premium Member Only 1,027.55 1,122.68 1,225.76 1,344.70 1,436.33

Ono Pharmaceutical Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted Book per Share Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1,344.70 1,367.74 1,389.36 1,420.44 1,436.33

TSE:4528 vs LLY, JNJ, ABBV: Cyclically Adjusted Book per Share Comparison

For the Drug Manufacturers - General subindustry, Ono Pharmaceutical Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ono Pharmaceutical Co Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Ono Pharmaceutical Co's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Ono Pharmaceutical Co's Cyclically Adjusted PB Ratio falls into.


TSE:4528
89GF Score
Ono Pharmaceutical Co Ltd TSE:4528
Cyclically Adjusted Book per Share is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ono Pharmaceutical Co Cyclically Adjusted Book per Share Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Book per Share and the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years.

What is Cyclically Adjusted Book per Share? How do we calculate Cyclically Adjusted Book per Share?

Cyclically Adjusted Book per Share is the average of the inflation adjusted Book Value per Share of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the Cyclically Adjusted Book per Share of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the book value per share from 2001 through 2010.

We adjusted the 2001 book value per share data with the total inflation from 2001 through 2010 to the equivalent book value in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart's book value is $1 a share in 2001, then the 2001's equivalent book value in 2010 is $1.4 a share. If Wal-Mart's book value is $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 book value in 2010 is $1.35. So on and so forth, you get the equivalent book value per share of past 10 years. Then you add them together and divided the sum by the count to get Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Ono Pharmaceutical Co's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book= Book Value per Share /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=1810.416/112.7000*112.7000
=1,810.416

Current CPI (Mar. 2026) = 112.7000.

Ono Pharmaceutical Co Quarterly Data

Book Value per Share CPI Adj_Book
201606 892.221 98.100 1,025.008
201609 916.197 98.000 1,053.627
201612 951.571 98.400 1,089.858
201703 979.418 98.100 1,125.183
201706 969.750 98.500 1,109.552
201709 976.471 98.800 1,113.849
201712 1,016.228 99.400 1,152.202
201803 1,019.972 99.200 1,158.779
201806 1,053.268 99.200 1,196.606
201809 1,098.512 99.900 1,239.262
201812 1,058.144 99.700 1,196.117
201903 1,084.083 99.700 1,225.438
201906 1,079.033 99.800 1,218.507
201909 1,100.753 100.100 1,239.309
201912 1,172.067 100.500 1,314.348
202003 1,126.954 100.300 1,266.278
202006 1,168.787 99.900 1,318.541
202009 1,212.182 99.900 1,367.497
202012 1,247.414 99.300 1,415.746
202103 1,270.446 99.900 1,433.226
202106 1,291.202 99.500 1,462.497
202109 1,350.413 100.100 1,520.395
202112 1,338.735 100.100 1,507.247
202203 1,343.395 101.100 1,497.533
202206 1,375.958 101.800 1,523.286
202209 1,442.768 103.100 1,577.109
202212 1,477.309 104.100 1,599.354
202303 1,519.184 104.400 1,639.962
202306 1,561.405 105.200 1,672.722
202309 1,617.309 106.200 1,716.297
202312 1,652.769 106.800 1,744.074
202403 1,688.419 107.200 1,775.045
202406 1,726.263 108.200 1,798.058
202409 1,665.850 108.900 1,723.979
202412 1,737.075 110.700 1,768.458
202503 1,665.594 111.100 1,689.581
202506 1,644.705 111.700 1,659.429
202509 1,715.974 112.000 1,726.699
202512 1,786.882 113.000 1,782.138
202603 1,810.416 112.700 1,810.416

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

What does a Cyclically Adjusted Book per Share of 円1,436.33 mean?
Ono Pharmaceutical Co (TSE:4528) has a Cyclically Adjusted Book per Share of 円1,436.33 as of Mar. 2026. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors.
Is Ono Pharmaceutical Co's Cyclically Adjusted Book per Share too high?
Ono Pharmaceutical Co's current Cyclically Adjusted Book per Share is 円1,436.33. Overall, Ono Pharmaceutical Co has a GF Score™ of 89/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Ono Pharmaceutical Co's Cyclically Adjusted Book per Share compare to LLY and JNJ?
Ono Pharmaceutical Co's Cyclically Adjusted Book per Share of 円1,436.33 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted Book per Share for a Drug Manufacturers company?
A good Cyclically Adjusted Book per Share depends on the Drug Manufacturers industry context. However, Cyclically Adjusted Book per Share should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted Book per Share mean?
A high Cyclically Adjusted Book per Share can signal that a stock is expensive relative to its fundamentals. Cyclically adjusted book value per share represents the company's inflation-adjusted book value per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors. Ono Pharmaceutical Co's current Cyclically Adjusted Book per Share is 円1,436.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ono Pharmaceutical Co stock overvalued right now?
Based on GuruFocus' analysis, Ono Pharmaceutical Co (TSE:4528) is currently considered Fairly Valued. The stock's GF Value™ is 円2,239.11, compared to a current price of 円2,400.50 — trading 7.2% above its estimated fair value. The current Cyclically Adjusted Book per Share is 円1,436.33. Ono Pharmaceutical Co's overall GF Score™ is 89/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted Book per Share calculated?
Cyclically Adjusted Book per Share is calculated from a company's financial statements. For Ono Pharmaceutical Co (TSE:4528), the current Cyclically Adjusted Book per Share is 円1,436.33 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ono Pharmaceutical Co (TSE:4528) Overvalued in 2026?

Based on GuruFocus' analysis, Ono Pharmaceutical Co stock appears to be overvalued. The current stock price of 円2,400.50 is trading 7.2% above its estimated GF Value™ of 円2,239.11. GuruFocus considers Ono Pharmaceutical Co to be Fairly Valued.

Key valuation signals for TSE:4528:

  • Cyclically Adjusted Book per Share: 円1,436.33
  • GF Value™: 円2,239.11 vs. price of 円2,400.50 (7.2% above fair value)
  • GF Score™: 89/100 with 4 warning signs

No single metric tells the full story. See the TSE:4528 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ono Pharmaceutical Co Business Description

Other Exchanges OPHLY:USAON4:Germany
Address 1-8-2 Kyutarocho, Chuo-ku, Osaka, JPN, 541-8564
Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. The vast majority of the company's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of the company's sales is generated in Japan, followed by the rest of Asia and Europe.
89GF Score

Get the complete analysis for TSE:4528

Cyclically Adjusted Book per Share is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,400.50
Price
円2,239.11
GF Value