Ono Pharmaceutical Co (TSE:4528) ROA %: 0.30% (As of Mar. 2026) — 97% Below Median


TSE:4528 Ono Pharmaceutical Co Ltd TSE:4528
88 GF Score
Price 円2,377.50
GF Value 円2,255.53
Valuation Fairly Valued
! 2 Warning Signs
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What is Ono Pharmaceutical Co ROA %?

Ono Pharmaceutical Co TSE:4528 +1.58% 88 ROA % is 0.30% as of Mar. 2026, which is 97% below its 10-year median of 9.32. GuruFocus rates TSE:4528 with a GF Score™ of 88/100 and a GF Value™ of 円2,255.53 (Fairly Valued). The stock has 2 warning signs investors should review. Among 1,003 Drug Manufacturers companies, Ono Pharmaceutical Co ranks better than 69.69% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Ono Pharmaceutical Co's annualized Net Income for the quarter that ended in Mar. 2026 was 円3,272 Mil. Ono Pharmaceutical Co's average Total Assets over the quarter that ended in Mar. 2026 was 円1,095,456 Mil. Therefore, Ono Pharmaceutical Co's annualized ROA % for the quarter that ended in Mar. 2026 was 0.30%.

The historical rank and industry rank for Ono Pharmaceutical Co's ROA % or its related term are showing as below:

TSE:4528' s ROA % Range Over the Past 10 Years
Min: 5.06   Med: 9.32   Max: 14.25
Current: 6.54

During the past 13 years, Ono Pharmaceutical Co's highest ROA % was 14.25%. The lowest was 5.06%. And the median was 9.32%.

TSE:4528's ROA % is ranked better than
69.69% of 1003 companies
in the Drug Manufacturers industry
Industry Median: 2.69 vs TSE:4528: 6.54

Ono Pharmaceutical Co  (TSE:4528) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=3272/1095456
=(Net Income / Revenue)*(Revenue / Total Assets)
=(3272 / 474996)*(474996 / 1095456)
=Net Margin %*Asset Turnover
=0.69 %*0.4336
=0.30 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Ono Pharmaceutical Co ROA % Related Terms


Ono Pharmaceutical Co ROA % Historical Data

* Premium members only.

The historical data trend for Ono Pharmaceutical Co's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co ROA % Chart

Ono Pharmaceutical Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 10.85 13.90 14.25 5.06 6.43

Ono Pharmaceutical Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.44 6.77 8.61 10.77 0.30

TSE:4528 vs LLY, JNJ, ABBV: ROA % Comparison

For the Drug Manufacturers - General subindustry, Ono Pharmaceutical Co's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ono Pharmaceutical Co ROA % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Ono Pharmaceutical Co's ROA % distribution charts can be found below:

* The bar in red indicates where Ono Pharmaceutical Co's ROA % falls into.


TSE:4528
88GF Score
Ono Pharmaceutical Co Ltd TSE:4528
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ono Pharmaceutical Co ROA % Calculation

Ono Pharmaceutical Co's annualized ROA % for the fiscal year that ended in Mar. 2026 is calculated as:

ROA %=Net Income (A: Mar. 2026 )/( (Total Assets (A: Mar. 2025 )+Total Assets (A: Mar. 2026 ))/ count )
=69767/( (1064046+1106515)/ 2 )
=69767/1085280.5
=6.43 %

Ono Pharmaceutical Co's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=3272/( (1084397+1106515)/ 2 )
=3272/1095456
=0.30 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of 0.30% mean?
Ono Pharmaceutical Co (TSE:4528) has a ROA % of 0.30% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Ono Pharmaceutical Co and its competitors. This is 97% below median its historical median of 9.32. Over the past decade, Ono Pharmaceutical Co's ROA % has ranged from 5.06 to 14.25. According to the industry distribution chart, Ono Pharmaceutical Co ranks #304 out of 1003 companies in the Drug Manufacturers industry, placing it in the top 30.3%.
Is Ono Pharmaceutical Co's ROA % too high?
Ono Pharmaceutical Co's current ROA % of 0.30% is 97% below median its 10-year median of 9.32. Over the past 10 years, this metric has ranged from a low of 5.06 to a high of 14.25. The Drug Manufacturers industry median ROA % is 2.69. Ono Pharmaceutical Co's value of 0.30% is 88.8% below this industry median. Based on the distribution chart, Ono Pharmaceutical Co ranks #304 out of 1003 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Ono Pharmaceutical Co has a GF Score™ of 88/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Ono Pharmaceutical Co's ROA % compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Ono Pharmaceutical Co ranks #304 out of 1003 companies for ROA %. This puts Ono Pharmaceutical Co in the upper half of its industry. The industry median ROA % is 2.69. Ono Pharmaceutical Co's value of 0.30% is 88.8% below this benchmark. Historically, Ono Pharmaceutical Co's own ROA % has ranged from 5.06 to 14.25 over the past decade. While the company's 10-year median is 9.32 vs. the industry median of 2.69, Ono Pharmaceutical Co has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Drug Manufacturers company?
The median ROA % among Drug Manufacturers companies is 2.69, based on 1,003 companies in the industry. Companies in the top quartile (top 25%) have a ROA % significantly above this median, while those in the bottom quartile fall well below. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Ono Pharmaceutical Co's current ROA % of 0.30% is 88.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Ono Pharmaceutical Co and its competitors. For the Drug Manufacturers industry, the median ROA % is 2.69 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ono Pharmaceutical Co's current ROA % is 0.30%, which is 97% below median its own 10-year median of 9.32. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ono Pharmaceutical Co stock overvalued right now?
Based on GuruFocus' analysis, Ono Pharmaceutical Co (TSE:4528) is currently considered Fairly Valued. The stock's GF Value™ is 円2,255.53, compared to a current price of 円2,377.50 — trading 5.4% above its estimated fair value. The current ROA % is 0.30%, which is 97% below median its 10-year median of 9.32 and 88.8% below the Drug Manufacturers industry median of 2.69. Ono Pharmaceutical Co's overall GF Score™ is 88/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Ono Pharmaceutical Co (TSE:4528), the current ROA % is 0.30% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ono Pharmaceutical Co (TSE:4528) Overvalued in 2026?

Based on GuruFocus' analysis, Ono Pharmaceutical Co stock appears to be overvalued. The current stock price of 円2,377.50 is trading 5.4% above its estimated GF Value™ of 円2,255.53. GuruFocus considers Ono Pharmaceutical Co to be Fairly Valued.

Key valuation signals for TSE:4528:

  • ROA %: 0.30% (97% below median its 10-year median of 9.32)
  • GF Value™: 円2,255.53 vs. price of 円2,377.50 (5.4% above fair value)
  • GF Score™: 88/100 with 2 warning signs
  • Industry Position: 88.8% below the Drug Manufacturers median (#304 of 1003)

No single metric tells the full story. See the TSE:4528 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ono Pharmaceutical Co Business Description

Other Exchanges OPHLY:USAON4:Germany
Address 1-8-2 Kyutarocho, Chuo-ku, Osaka, JPN, 541-8564
Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. The vast majority of the company's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of the company's sales is generated in Japan, followed by the rest of Asia and Europe.
88GF Score

Get the complete analysis for TSE:4528

ROA % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,377.50
Price
円2,255.53
GF Value