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Vertex Pharmaceuticals (LTS:0QZU) Cyclically Adjusted Price-to-FCF : 64.81 (As of Jun. 05, 2025)


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What is Vertex Pharmaceuticals Cyclically Adjusted Price-to-FCF?

As of today (2025-06-05), Vertex Pharmaceuticals's current share price is $447.8201. Vertex Pharmaceuticals's Cyclically Adjusted FCF per Share for the quarter that ended in Mar. 2025 was $6.91. Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF for today is 64.81.

The historical rank and industry rank for Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF or its related term are showing as below:

LTS:0QZU' s Cyclically Adjusted Price-to-FCF Range Over the Past 10 Years
Min: 55.85   Med: 72.95   Max: 924.7
Current: 64.11

During the past years, Vertex Pharmaceuticals's highest Cyclically Adjusted Price-to-FCF was 924.70. The lowest was 55.85. And the median was 72.95.

LTS:0QZU's Cyclically Adjusted Price-to-FCF is ranked worse than
60.19% of 103 companies
in the Biotechnology industry
Industry Median: 49.09 vs LTS:0QZU: 64.11

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Price-to-FCF. The Cyclically Adjusted FCF per Share is the average of the inflation adjusted free cash flow per share of a company over the past 10 years.

Vertex Pharmaceuticals's adjusted free cash flow per share data for the three months ended in Mar. 2025 was $2.999. Add all the adjusted free cash flow per share for the past 10 years together and divide 10 will get our Cyclically Adjusted FCF per Share, which is $6.91 for the trailing ten years ended in Mar. 2025.

Shiller PE for Stocks: The True Measure of Stock Valuation


Vertex Pharmaceuticals Cyclically Adjusted Price-to-FCF Historical Data

The historical data trend for Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

* Premium members only.

Vertex Pharmaceuticals Cyclically Adjusted Price-to-FCF Chart

Vertex Pharmaceuticals Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Cyclically Adjusted Price-to-FCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only 111.35 68.93 60.17 64.67 62.56

Vertex Pharmaceuticals Quarterly Data
Jun20 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25
Cyclically Adjusted Price-to-FCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 60.40 84.36 75.88 62.56 69.72

Competitive Comparison of Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF

For the Biotechnology subindustry, Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF, along with its competitors' market caps and Cyclically Adjusted Price-to-FCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF Distribution in the Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF distribution charts can be found below:

* The bar in red indicates where Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF falls into.


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Vertex Pharmaceuticals Cyclically Adjusted Price-to-FCF Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted Price-to-FCF takes the Free Cash Flow per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/FCF calculation. Because it considers this 10-year average, it's often referred to as the CAPFCF Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted Price-to-FCF.

Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF for today is calculated as

Cyclically Adjusted Price-to-FCF=Share Price/ Cyclically Adjusted FCF per Share
=447.8201/6.91
=64.81

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Vertex Pharmaceuticals's Cyclically Adjusted FCF per Share for the quarter that ended in Mar. 2025 is calculated as:

For example, Vertex Pharmaceuticals's adjusted Free Cash Flow per Share data for the three months ended in Mar. 2025 was:

Adj_FreeCashFlowPerShare=Free Cash Flow per Share/CPI of Mar. 2025 (Change)*Current CPI (Mar. 2025)
=2.999/134.9266*134.9266
=2.999

Current CPI (Mar. 2025) = 134.9266.

Vertex Pharmaceuticals Quarterly Data

Free Cash Flow per Share CPI Adj_FreeCashFlowPerShare
201506 -0.514 100.684 -0.689
201509 -0.293 100.392 -0.394
201512 0.068 99.792 0.092
201603 -0.111 100.470 -0.149
201606 0.102 101.688 0.135
201609 0.211 101.861 0.279
201612 0.530 101.863 0.702
201703 1.024 102.862 1.343
201706 0.653 103.349 0.853
201709 -0.071 104.136 -0.092
201712 0.719 104.011 0.933
201803 0.864 105.290 1.107
201806 1.130 106.317 1.434
201809 1.387 106.507 1.757
201812 1.151 105.998 1.465
201903 1.179 107.251 1.483
201906 1.722 108.070 2.150
201909 1.192 108.329 1.485
201912 1.637 108.420 2.037
202003 3.022 108.902 3.744
202006 3.875 108.767 4.807
202009 2.776 109.815 3.411
202012 1.697 109.897 2.084
202103 3.246 111.754 3.919
202106 -0.956 114.631 -1.125
202109 3.369 115.734 3.928
202112 3.633 117.630 4.167
202203 3.461 121.301 3.850
202206 4.200 125.017 4.533
202209 3.473 125.227 3.742
202212 4.014 125.222 4.325
202303 3.295 127.348 3.491
202306 4.127 128.729 4.326
202309 4.711 129.860 4.895
202312 0.454 129.419 0.473
202403 4.053 131.776 4.150
202406 -14.840 132.554 -15.106
202409 4.989 133.029 5.060
202412 1.912 133.157 1.937
202503 2.999 134.927 2.999

Add all the adjusted free cash flow per share together and divide 10 will get our Cyclically Adjusted FCF per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.


Vertex Pharmaceuticals  (LTS:0QZU) Cyclically Adjusted Price-to-FCF Explanation

Compared with the regular Price-to-Free-Cash-Flow, which works poorly for cyclical businesses, the Cyclically Adjusted Price-to-FCF smoothed out the fluctuations of free cash flow during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted Price-to-FCF should give similar results to regular Price-to-Free-Cash-Flow.


Vertex Pharmaceuticals Cyclically Adjusted Price-to-FCF Related Terms

Thank you for viewing the detailed overview of Vertex Pharmaceuticals's Cyclically Adjusted Price-to-FCF provided by GuruFocus.com. Please click on the following links to see related term pages.


Vertex Pharmaceuticals Business Description

Address
50 Northern Avenue, Boston, MA, USA, 02210
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.

Vertex Pharmaceuticals Headlines

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