ARWR (Arrowhead Pharmaceuticals) Cyclically Adjusted PS Ratio: (As of Aug. 08, 2026)

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Director of Data and Quant Analytics at GuruFocus
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ARWR Arrowhead Pharmaceuticals Inc ARWR
45 GF Score
Price $87.65
GF Value $60.20
Valuation Significantly Overvalued
! 6 Warning Signs
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What is Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Arrowhead Pharmaceuticals  (NAS:ARWR) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio Related Terms


Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Arrowhead Pharmaceuticals's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio Chart

Arrowhead Pharmaceuticals Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 124.89 42.44 25.83 0.00 18.36

Arrowhead Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 9.52 18.36 31.89 28.77 36.04

ARWR vs AXSM, MDGL, BMRN: Cyclically Adjusted PS Ratio Comparison

For the Biotechnology subindustry, Arrowhead Pharmaceuticals's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Arrowhead Pharmaceuticals's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Arrowhead Pharmaceuticals's Cyclically Adjusted PS Ratio falls into.


ARWR
45GF Score
Arrowhead Pharmaceuticals Inc ARWR
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Arrowhead Pharmaceuticals Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Arrowhead Pharmaceuticals's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Arrowhead Pharmaceuticals's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.525/333.9520*333.9520
=0.525

Current CPI (Jun. 2026) = 333.9520.

Arrowhead Pharmaceuticals Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 0.000 241.428 0.000
201612 0.061 241.432 0.084
201703 0.120 243.801 0.164
201706 0.125 244.955 0.170
201709 0.117 246.819 0.158
201712 0.047 246.524 0.064
201803 0.008 249.554 0.011
201806 0.008 251.989 0.011
201809 0.128 252.439 0.169
201812 0.363 251.233 0.483
201903 0.491 254.202 0.645
201906 0.432 256.143 0.563
201909 0.429 256.759 0.558
201912 0.303 256.974 0.394
202003 0.231 258.115 0.299
202006 0.269 257.797 0.348
202009 0.075 260.280 0.096
202012 0.207 260.474 0.265
202103 0.316 264.877 0.398
202106 0.441 271.696 0.542
202109 0.367 274.310 0.447
202112 0.262 278.802 0.314
202203 1.407 287.504 1.634
202206 0.306 296.311 0.345
202209 0.298 296.808 0.335
202212 0.590 296.797 0.664
202303 1.353 301.836 1.497
202306 0.148 305.109 0.162
202309 0.150 307.789 0.163
202312 0.033 306.746 0.036
202403 0.000 312.332 0.000
202406 0.000 314.175 0.000
202409 0.000 315.301 0.000
202412 0.020 315.605 0.021
202503 4.035 319.799 4.214
202506 0.200 322.561 0.207
202509 1.860 324.800 1.912
202512 1.876 324.054 1.933
202603 0.518 330.213 0.524
202606 0.525 333.952 0.525

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Arrowhead Pharmaceuticals (ARWR) Overvalued in 2026?

Based on GuruFocus' analysis, Arrowhead Pharmaceuticals stock appears to be overvalued. The current stock price of $87.65 is trading 45.6% above its estimated GF Value™ of $60.20. GuruFocus considers Arrowhead Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for ARWR:

  • Cyclically Adjusted PS Ratio:
  • GF Value™: $60.20 vs. price of $87.65 (45.6% above fair value)
  • GF Score™: 45/100 with 6 warning signs

No single metric tells the full story. See the ARWR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Arrowhead Pharmaceuticals Business Description

Address 177 E Colorado Boulevard, Suite 700, Pasadena, CA, USA, 91105
Arrowhead Pharmaceuticals Inc is a commercial-stage pharmaceutical company. It is focused on the development of medicines for diseases associated with genetic abnormalities or protein overproduction. The company develops potential RNAi therapies designed to inhibit the expression of genes known to trigger diseases. Its portfolio includes potential drugs targeting Cardiometabolic, Neuromuscular, Pulmonary, Liver, and other diseases. The company also develops RNAi products and clinical candidates designed to target different cell types within the body.
45GF Score

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Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$87.65
Price
$60.20
GF Value