ARWR (Arrowhead Pharmaceuticals) Pretax Margin %: -186.56% (As of Mar. 2026)


ARWR Arrowhead Pharmaceuticals Inc ARWR
49 GF Score
Price $78.89
GF Value $52.13
Valuation Significantly Overvalued
! 6 Warning Signs
View Full Analysis

What is Arrowhead Pharmaceuticals Pretax Margin %?

Arrowhead Pharmaceuticals ARWR -0.48% 49 Pretax Margin % is -186.56% as of Mar. 2026. GuruFocus rates ARWR with a GF Score™ of 49/100 and a GF Value™ of $52.13 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 946 Biotechnology companies, Arrowhead Pharmaceuticals ranks better than 58.46% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Arrowhead Pharmaceuticals's Pre-Tax Income for the three months ended in Mar. 2026 was $-137.6 Mil. Arrowhead Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was $73.7 Mil. Therefore, Arrowhead Pharmaceuticals's pretax margin for the quarter that ended in Mar. 2026 was -186.56%.

The historical rank and industry rank for Arrowhead Pharmaceuticals's Pretax Margin % or its related term are showing as below:

ARWR' s Pretax Margin % Range Over the Past 10 Years
Min: -51722.15   Med: -98.97   Max: 40.37
Current: -40.56


ARWR's Pretax Margin % is ranked better than
58.46% of 946 companies
in the Biotechnology industry
Industry Median: -90.5 vs ARWR: -40.56

Arrowhead Pharmaceuticals  (NAS:ARWR) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Arrowhead Pharmaceuticals Pretax Margin % Related Terms


Arrowhead Pharmaceuticals Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Arrowhead Pharmaceuticals's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Arrowhead Pharmaceuticals Pretax Margin % Chart

Arrowhead Pharmaceuticals Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -101.85 -71.01 -85.78 -17,247.54 6.21

Arrowhead Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 68.11 -644.97 14.08 10.71 -186.56

ARWR vs BMRN, MDGL, CYTK: Pretax Margin % Comparison

For the Biotechnology subindustry, Arrowhead Pharmaceuticals's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Arrowhead Pharmaceuticals Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Arrowhead Pharmaceuticals's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Arrowhead Pharmaceuticals's Pretax Margin % falls into.


ARWR
49GF Score
Arrowhead Pharmaceuticals Inc ARWR
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Arrowhead Pharmaceuticals Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Arrowhead Pharmaceuticals's Pretax Margin for the fiscal year that ended in Sep. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Sep. 2025 )/Revenue (A: Sep. 2025 )
=51.533/829.448
=6.21 %

Arrowhead Pharmaceuticals's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-137.565/73.737
=-186.56 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -186.56% mean?
Arrowhead Pharmaceuticals (ARWR) has a Pretax Margin % of -186.56% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Arrowhead Pharmaceuticals and its competitors. According to the industry distribution chart, Arrowhead Pharmaceuticals ranks #393 out of 946 companies in the Biotechnology industry, placing it in the top 41.5%.
Is Arrowhead Pharmaceuticals' Pretax Margin % too high?
Arrowhead Pharmaceuticals' current Pretax Margin % is -186.56%. Based on the distribution chart, Arrowhead Pharmaceuticals ranks #393 out of 946 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Arrowhead Pharmaceuticals has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Arrowhead Pharmaceuticals' Pretax Margin % compare to BMRN and MDGL?
According to the Biotechnology industry distribution chart, Arrowhead Pharmaceuticals ranks #393 out of 946 companies for Pretax Margin %. This puts Arrowhead Pharmaceuticals in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Arrowhead Pharmaceuticals and its competitors. Arrowhead Pharmaceuticals's current Pretax Margin % is -186.56%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Arrowhead Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Arrowhead Pharmaceuticals (ARWR) is currently considered Significantly Overvalued. The stock's GF Value™ is $52.13, compared to a current price of $78.89 — trading 51.3% above its estimated fair value. The current Pretax Margin % is -186.56%. Arrowhead Pharmaceuticals' overall GF Score™ is 49/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Arrowhead Pharmaceuticals (ARWR), the current Pretax Margin % is -186.56% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Arrowhead Pharmaceuticals (ARWR) Overvalued in 2026?

Based on GuruFocus' analysis, Arrowhead Pharmaceuticals stock appears to be overvalued. The current stock price of $78.89 is trading 51.3% above its estimated GF Value™ of $52.13. GuruFocus considers Arrowhead Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for ARWR:

  • Pretax Margin %: -186.56%
  • GF Value™: $52.13 vs. price of $78.89 (51.3% above fair value)
  • GF Score™: 49/100 with 6 warning signs

No single metric tells the full story. See the ARWR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Arrowhead Pharmaceuticals Business Description

Address 177 E Colorado Boulevard, Suite 700, Pasadena, CA, USA, 91105
Arrowhead Pharmaceuticals Inc is a commercial-stage pharmaceutical company. It is focused on the development of medicines for diseases associated with genetic abnormalities or protein overproduction. The company develops potential RNAi therapies designed to inhibit the expression of genes known to trigger diseases. Its portfolio includes potential drugs targeting Cardiometabolic, Neuromuscular, Pulmonary, Liver, and other diseases. The company also develops RNAi products and clinical candidates designed to target different cell types within the body.
49GF Score

Get the complete analysis for ARWR

Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$78.89
Price
$52.13
GF Value